Ion Channels and Ion Pumps: Metabolic and Endocrine Relationships in Biology and Clinical Medicine
Omnis cellula e cellula, "every cell from a cell," was dogma to the 19th century cellular physiologist and the cornerstone of Virchow's Cellular pathologie. "Spread out a cell into a layer and you will find that, in ceasing to be a cell, it has ceased to act as such," wrot...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
1994
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| Schriftenreihe: | Endocrinology and Metabolism, Progress in Research and Clinical Practice
6 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Omnis cellula e cellula, "every cell from a cell," was dogma to the 19th century cellular physiologist and the cornerstone of Virchow's Cellular pathologie. "Spread out a cell into a layer and you will find that, in ceasing to be a cell, it has ceased to act as such," wrote the British 1 physiologist G . R. Lewes more than a century age. "The cell remains vital as long as its wall remains intact . . . " keeping its content "pure and clear" and thus preserving the "vital principle" within, echoed Claude 2 Bernard a few years later. The notion of the cell membrane as a pro tecting envelope held sway until it became clear that it could not account for the "coalescence" of poorly differentiated embryonic "vesicles" and for their transformation into "cell-like structures" capable of auto regulation and yet subject to what the grandfather of one of us defined as the "federal obligations imposed by the whole organism. ,,3 A new concept was needed, and soon the membrane was described as a structure capable of uniting as well as separating adjacent cells. Morphologic evidence for this dual function was obtained several years later when the electron microscope revealed the existence of tight and gap junc tions which, acting as intercellular bonds and channels, allowed the cells to communicate with one another and thus coordinate their biologic activities |
| Beschreibung: | 1 Online-Ressource (XX, 587 p) |
| ISBN: | 9781461225966 |
| DOI: | 10.1007/978-1-4612-2596-6 |
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| 520 | |a Omnis cellula e cellula, "every cell from a cell," was dogma to the 19th century cellular physiologist and the cornerstone of Virchow's Cellular pathologie. "Spread out a cell into a layer and you will find that, in ceasing to be a cell, it has ceased to act as such," wrote the British 1 physiologist G . R. Lewes more than a century age. "The cell remains vital as long as its wall remains intact . . . " keeping its content "pure and clear" and thus preserving the "vital principle" within, echoed Claude 2 Bernard a few years later. The notion of the cell membrane as a pro tecting envelope held sway until it became clear that it could not account for the "coalescence" of poorly differentiated embryonic "vesicles" and for their transformation into "cell-like structures" capable of auto regulation and yet subject to what the grandfather of one of us defined as the "federal obligations imposed by the whole organism. ,,3 A new concept was needed, and soon the membrane was described as a structure capable of uniting as well as separating adjacent cells. Morphologic evidence for this dual function was obtained several years later when the electron microscope revealed the existence of tight and gap junc tions which, acting as intercellular bonds and channels, allowed the cells to communicate with one another and thus coordinate their biologic activities | ||
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Datensatz im Suchindex
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| isbn | 9781461225966 |
| language | English |
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| series2 | Endocrinology and Metabolism, Progress in Research and Clinical Practice |
| spelling | Ion Channels and Ion Pumps Metabolic and Endocrine Relationships in Biology and Clinical Medicine edited by Piero P. Foà, Mary F. Walsh New York, NY Springer New York 1994 1 Online-Ressource (XX, 587 p) txt rdacontent c rdamedia cr rdacarrier Endocrinology and Metabolism, Progress in Research and Clinical Practice 6 Omnis cellula e cellula, "every cell from a cell," was dogma to the 19th century cellular physiologist and the cornerstone of Virchow's Cellular pathologie. "Spread out a cell into a layer and you will find that, in ceasing to be a cell, it has ceased to act as such," wrote the British 1 physiologist G . R. Lewes more than a century age. "The cell remains vital as long as its wall remains intact . . . " keeping its content "pure and clear" and thus preserving the "vital principle" within, echoed Claude 2 Bernard a few years later. The notion of the cell membrane as a pro tecting envelope held sway until it became clear that it could not account for the "coalescence" of poorly differentiated embryonic "vesicles" and for their transformation into "cell-like structures" capable of auto regulation and yet subject to what the grandfather of one of us defined as the "federal obligations imposed by the whole organism. ,,3 A new concept was needed, and soon the membrane was described as a structure capable of uniting as well as separating adjacent cells. Morphologic evidence for this dual function was obtained several years later when the electron microscope revealed the existence of tight and gap junc tions which, acting as intercellular bonds and channels, allowed the cells to communicate with one another and thus coordinate their biologic activities Cell Biology Human Physiology Biochemistry, general Cytology Human physiology Biochemistry Ionenpumpe (DE-588)4162339-3 gnd rswk-swf Ionenkanal (DE-588)4138699-1 gnd rswk-swf Ionenpumpe (DE-588)4162339-3 s DE-604 Ionenkanal (DE-588)4138699-1 s Foà, Piero P. edt Walsh, Mary F. edt Erscheint auch als Druck-Ausgabe 9781461275992 Erscheint auch als Druck-Ausgabe 9780387940830 Erscheint auch als Druck-Ausgabe 9781461225973 https://doi.org/10.1007/978-1-4612-2596-6 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Ion Channels and Ion Pumps Metabolic and Endocrine Relationships in Biology and Clinical Medicine Cell Biology Human Physiology Biochemistry, general Cytology Human physiology Biochemistry Ionenpumpe (DE-588)4162339-3 gnd Ionenkanal (DE-588)4138699-1 gnd |
| subject_GND | (DE-588)4162339-3 (DE-588)4138699-1 |
| title | Ion Channels and Ion Pumps Metabolic and Endocrine Relationships in Biology and Clinical Medicine |
| title_auth | Ion Channels and Ion Pumps Metabolic and Endocrine Relationships in Biology and Clinical Medicine |
| title_exact_search | Ion Channels and Ion Pumps Metabolic and Endocrine Relationships in Biology and Clinical Medicine |
| title_full | Ion Channels and Ion Pumps Metabolic and Endocrine Relationships in Biology and Clinical Medicine edited by Piero P. Foà, Mary F. Walsh |
| title_fullStr | Ion Channels and Ion Pumps Metabolic and Endocrine Relationships in Biology and Clinical Medicine edited by Piero P. Foà, Mary F. Walsh |
| title_full_unstemmed | Ion Channels and Ion Pumps Metabolic and Endocrine Relationships in Biology and Clinical Medicine edited by Piero P. Foà, Mary F. Walsh |
| title_short | Ion Channels and Ion Pumps |
| title_sort | ion channels and ion pumps metabolic and endocrine relationships in biology and clinical medicine |
| title_sub | Metabolic and Endocrine Relationships in Biology and Clinical Medicine |
| topic | Cell Biology Human Physiology Biochemistry, general Cytology Human physiology Biochemistry Ionenpumpe (DE-588)4162339-3 gnd Ionenkanal (DE-588)4138699-1 gnd |
| topic_facet | Cell Biology Human Physiology Biochemistry, general Cytology Human physiology Biochemistry Ionenpumpe Ionenkanal |
| url | https://doi.org/10.1007/978-1-4612-2596-6 |
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