The Construction of Analogy-Based Research Programs: The Lock-and-Key Analogy in 20th Century Biochemistry
When the German chemist Emil Fischer presented his key-lock hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical struc...
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| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Bielefeld
transcript-Verlag
[2019]
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| Schriftenreihe: | Science Studies
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| Schlagworte: | |
| Online-Zugang: | DE-B1533 DE-1043 DE-1046 DE-858 DE-Aug4 DE-859 DE-860 DE-473 DE-355 DE-706 DE-739 URL des Erstveröffentlichers |
| Zusammenfassung: | When the German chemist Emil Fischer presented his key-lock hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity.Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling |
| Beschreibung: | Description based on online resource; title from PDF title page (publisher's Web site, viewed 30. Apr 2019) |
| Beschreibung: | 1 online resource |
| ISBN: | 9783839444429 |
| DOI: | 10.14361/9783839444429 |
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| spelling | Mertens, Rebecca 1984- Verfasser (DE-588)1182339743 aut The Construction of Analogy-Based Research Programs The Lock-and-Key Analogy in 20th Century Biochemistry Rebecca Mertens Bielefeld transcript-Verlag [2019] © 2019 1 online resource txt rdacontent c rdamedia cr rdacarrier Science Studies Description based on online resource; title from PDF title page (publisher's Web site, viewed 30. Apr 2019) When the German chemist Emil Fischer presented his key-lock hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity.Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling In English Analogy Biochemistry History of Science History Life Sciences Medicine Molecular Biology Philosophy of Science Research Program Science Sociology of Science HISTORY / General bisacsh https://doi.org/10.14361/9783839444429 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Mertens, Rebecca 1984- The Construction of Analogy-Based Research Programs The Lock-and-Key Analogy in 20th Century Biochemistry Analogy Biochemistry History of Science History Life Sciences Medicine Molecular Biology Philosophy of Science Research Program Science Sociology of Science HISTORY / General bisacsh |
| title | The Construction of Analogy-Based Research Programs The Lock-and-Key Analogy in 20th Century Biochemistry |
| title_auth | The Construction of Analogy-Based Research Programs The Lock-and-Key Analogy in 20th Century Biochemistry |
| title_exact_search | The Construction of Analogy-Based Research Programs The Lock-and-Key Analogy in 20th Century Biochemistry |
| title_full | The Construction of Analogy-Based Research Programs The Lock-and-Key Analogy in 20th Century Biochemistry Rebecca Mertens |
| title_fullStr | The Construction of Analogy-Based Research Programs The Lock-and-Key Analogy in 20th Century Biochemistry Rebecca Mertens |
| title_full_unstemmed | The Construction of Analogy-Based Research Programs The Lock-and-Key Analogy in 20th Century Biochemistry Rebecca Mertens |
| title_short | The Construction of Analogy-Based Research Programs |
| title_sort | the construction of analogy based research programs the lock and key analogy in 20th century biochemistry |
| title_sub | The Lock-and-Key Analogy in 20th Century Biochemistry |
| topic | Analogy Biochemistry History of Science History Life Sciences Medicine Molecular Biology Philosophy of Science Research Program Science Sociology of Science HISTORY / General bisacsh |
| topic_facet | Analogy Biochemistry History of Science History Life Sciences Medicine Molecular Biology Philosophy of Science Research Program Science Sociology of Science HISTORY / General |
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