Freeze drying of L-arginine-based protein formulations:
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis Book |
| Language: | English |
| Published: |
Erlangen ; Nürnberg
[2019]
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Enthält 5 Sonderdrucke |
| Physical Description: | 51 Seiten, 62 verschieden gezählte Seiten Illustrationen, Diagramme 21 cm |
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MARC
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| 044 | |a gw |c XA-DE | ||
| 049 | |a DE-29 |a DE-29T | ||
| 100 | 1 | |a Stärtzel, Peter Martin |d 1985- |e Verfasser |0 (DE-588)1180529146 |4 aut | |
| 245 | 1 | 0 | |a Freeze drying of L-arginine-based protein formulations |c vorgelegt von Peter Martin Stärtzel |
| 264 | 1 | |a Erlangen ; Nürnberg |c [2019] | |
| 300 | |a 51 Seiten, 62 verschieden gezählte Seiten |b Illustrationen, Diagramme |c 21 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Enthält 5 Sonderdrucke | ||
| 502 | |b Dissertation |c Friedrich-Alexander-Universität Erlangen-Nürnberg |d 2019 | ||
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| 650 | 0 | 7 | |a Gefriertrocknung |0 (DE-588)4156264-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Arginin |0 (DE-588)4142987-4 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4113937-9 |a Hochschulschrift |2 gnd-content | |
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Record in the Search Index
| _version_ | 1804179463173308416 |
|---|---|
| adam_text | TABLE
OF
CONTENT
1.
INTRODUCTION
[PL]
............................................................................................................................
1
2.
FUNDAMENTALS
AND
MAIN
TECHNIQUES
..........................................................................................
5
2.1
FREEZE
DRYING
...........................................................................................................................
5
2.1.1
FREEZING
[P2]
.....................................................................................................................
5
2.1.2
PRIMARY
DRYING
.................................................................................................................
7
2.1.3
SECONDARY
DRYING
.............................................................................................................
8
2.2
FREEZE
DRY
MICROSCOPY
...........................................................................................................
8
2.3
(MODULATED)
DIFFERENTIAL
SCANNING
CALORIMETRY
..................................................................
9
2.4
VISUAL
PRODUCT
DEFECT
CLASSIFICATION
[P3,
P4,
PS]
................................
10
2.5
QUANTIFICATION
OF
SAMPLE
CRYSTALLINITY
[PS]
.......................................................................
11
2.6
ESTIMATION
OF
MOLECULAR
MOBILITY
BASED
ON
MDSC
SOLID
STATE
ANALYSIS
[P3,
P4]
..........
12
2.7
INVESTIGATION
OF
PRODUCT
STORAGE
STABILITY
[P3,
P4]
..........................................................
13
3.
THE
INFLUENCE
OF
FORMULATION
COMPOSITION
AND
L-ARGININE
COUNTER
ION
ON
PRODUCT
PERFORMANCE
AND
PROTEIN
STABILITY
[P3]
...................................................................................
13
3.1
FREEZE
DRYING
AND
CHARACTERIZATION
OF
PLACEBO
FORMULATIONS
........................................
14
3.2
FREEZE
DRYING
AND
CHARACTERIZATION
OF
PROTEIN
FORMULATIONS
.........................................
17
3.3
PROTEIN
STABILITY
.....................................................................................................................
18
4.
OPTIMIZATION
OF
FORMULATION
DESIGN
AND
FREEZE
DRYING
PROCESS
CONDITIONS
[P4]
............ 21
4.1
CHARACTERIZATION
OF
FROZEN
SOLUTIONS
.................................................................................
21
4.2
FREEZE
DRYING
OF
L-ARGININE
CHLORIDE-BASED
BSA
SYSTEMS
..............................................
22
4.3
INFLUENCE
OF
THE
FREEZING
PROCEDURE
..................................................................................24
4.4
FREEZE
DRYING
OF
A
MAB
AND
STORAGE
STABILITY
...................................................................
26
5.
PARTIALLY
CRYSTALLINE
FORMULATION
SYSTEMS
CONTAINING
L-ARGININE
[PS]
................................
27
5.1
THERMAL
CHARACTERIZATION
OF
FROZEN
SOLUTIONS
..................................................................
28
5.2
CHARACTERIZATION
OF
FREEZE
DRIED
SOLIDS
.............................................................................
29
5.3
MANNITOL
CRYSTALLINITY
...........................................................................................................
31
5.4
PHYSICAL
STATE
OF
MANNITOL
...................................................................................................
32
6.
SUMMARY
AND
CONCLUSIONS
[PL]
................................................................................................
34
7.
LITERATURE
......................................................................................................................................
37
8.
CURRICULUM
VITAE
.........................................................................................................................
47
9.
APPENDIX
.......................................................................................................................................
48
|
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| author_GND | (DE-588)1180529146 |
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| author_sort | Stärtzel, Peter Martin 1985- |
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| bvnumber | BV045515862 |
| ctrlnum | (OCoLC)1136276592 (DE-599)DNB1180528611 |
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| genre_facet | Hochschulschrift |
| id | DE-604.BV045515862 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T08:20:16Z |
| institution | BVB |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030900255 |
| oclc_num | 1136276592 |
| open_access_boolean | |
| owner | DE-29 DE-29T |
| owner_facet | DE-29 DE-29T |
| physical | 51 Seiten, 62 verschieden gezählte Seiten Illustrationen, Diagramme 21 cm |
| publishDate | 2019 |
| publishDateSearch | 2019 |
| publishDateSort | 2019 |
| record_format | marc |
| spelling | Stärtzel, Peter Martin 1985- Verfasser (DE-588)1180529146 aut Freeze drying of L-arginine-based protein formulations vorgelegt von Peter Martin Stärtzel Erlangen ; Nürnberg [2019] 51 Seiten, 62 verschieden gezählte Seiten Illustrationen, Diagramme 21 cm txt rdacontent n rdamedia nc rdacarrier Enthält 5 Sonderdrucke Dissertation Friedrich-Alexander-Universität Erlangen-Nürnberg 2019 Proteinpräparat (DE-588)4247384-6 gnd rswk-swf Gefriertrocknung (DE-588)4156264-1 gnd rswk-swf Arginin (DE-588)4142987-4 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Proteinpräparat (DE-588)4247384-6 s Arginin (DE-588)4142987-4 s Gefriertrocknung (DE-588)4156264-1 s DE-604 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030900255&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Stärtzel, Peter Martin 1985- Freeze drying of L-arginine-based protein formulations Proteinpräparat (DE-588)4247384-6 gnd Gefriertrocknung (DE-588)4156264-1 gnd Arginin (DE-588)4142987-4 gnd |
| subject_GND | (DE-588)4247384-6 (DE-588)4156264-1 (DE-588)4142987-4 (DE-588)4113937-9 |
| title | Freeze drying of L-arginine-based protein formulations |
| title_auth | Freeze drying of L-arginine-based protein formulations |
| title_exact_search | Freeze drying of L-arginine-based protein formulations |
| title_full | Freeze drying of L-arginine-based protein formulations vorgelegt von Peter Martin Stärtzel |
| title_fullStr | Freeze drying of L-arginine-based protein formulations vorgelegt von Peter Martin Stärtzel |
| title_full_unstemmed | Freeze drying of L-arginine-based protein formulations vorgelegt von Peter Martin Stärtzel |
| title_short | Freeze drying of L-arginine-based protein formulations |
| title_sort | freeze drying of l arginine based protein formulations |
| topic | Proteinpräparat (DE-588)4247384-6 gnd Gefriertrocknung (DE-588)4156264-1 gnd Arginin (DE-588)4142987-4 gnd |
| topic_facet | Proteinpräparat Gefriertrocknung Arginin Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030900255&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT startzelpetermartin freezedryingoflargininebasedproteinformulations |