ODE/PDE [alpha]-synuclein models for Parkinson's disease:
ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a mechanism for the evolution of Parkinson's Disease (PD) based on the dynamics of the protein ?-synuclein, a monomer that has been implicated in this disease. Specifically, ?-synuclein morphs and aggregates into a polymer th...
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
London [England]
Academic Press
[2018]
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Schlagworte: | |
Online-Zugang: | FAW01 FLA01 Volltext |
Zusammenfassung: | ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a mechanism for the evolution of Parkinson's Disease (PD) based on the dynamics of the protein ?-synuclein, a monomer that has been implicated in this disease. Specifically, ?-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the ?-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms |
Beschreibung: | Includes bibliographical references and index |
Beschreibung: | 1 online resource |
ISBN: | 9780128148020 0128148020 |
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Datensatz im Suchindex
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any_adam_object | |
author | Schiesser, W. E. |
author_facet | Schiesser, W. E. |
author_role | aut |
author_sort | Schiesser, W. E. |
author_variant | w e s we wes |
building | Verbundindex |
bvnumber | BV045382939 |
collection | ZDB-33-ESD ZDB-33-EBS |
ctrlnum | (ZDB-33-ESD)on1023430596 (ZDB-33-EBS)on1023430596 (OCoLC)1023430596 (DE-599)BVBBV045382939 |
dewey-full | 616.8/33015118 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 616 - Diseases |
dewey-raw | 616.8/33015118 |
dewey-search | 616.8/33015118 |
dewey-sort | 3616.8 833015118 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
format | Electronic eBook |
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id | DE-604.BV045382939 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T08:16:39Z |
institution | BVB |
isbn | 9780128148020 0128148020 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030769272 |
oclc_num | 1023430596 |
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physical | 1 online resource |
psigel | ZDB-33-ESD ZDB-33-EBS ZDB-33-ESD FAW_PDA_ESD ZDB-33-ESD FLA_PDA_ESD |
publishDate | 2018 |
publishDateSearch | 2018 |
publishDateSort | 2018 |
publisher | Academic Press |
record_format | marc |
spelling | Schiesser, W. E. Verfasser aut ODE/PDE [alpha]-synuclein models for Parkinson's disease W.E. Schiesser London [England] Academic Press [2018] 1 online resource txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a mechanism for the evolution of Parkinson's Disease (PD) based on the dynamics of the protein ?-synuclein, a monomer that has been implicated in this disease. Specifically, ?-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the ?-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Parkinson's disease Mathematical models Erscheint auch als Druck-Ausgabe 9780128146149 https://www.sciencedirect.com/science/book/9780128146149 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Schiesser, W. E. ODE/PDE [alpha]-synuclein models for Parkinson's disease HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Parkinson's disease Mathematical models |
title | ODE/PDE [alpha]-synuclein models for Parkinson's disease |
title_auth | ODE/PDE [alpha]-synuclein models for Parkinson's disease |
title_exact_search | ODE/PDE [alpha]-synuclein models for Parkinson's disease |
title_full | ODE/PDE [alpha]-synuclein models for Parkinson's disease W.E. Schiesser |
title_fullStr | ODE/PDE [alpha]-synuclein models for Parkinson's disease W.E. Schiesser |
title_full_unstemmed | ODE/PDE [alpha]-synuclein models for Parkinson's disease W.E. Schiesser |
title_short | ODE/PDE [alpha]-synuclein models for Parkinson's disease |
title_sort | ode pde alpha synuclein models for parkinson s disease |
topic | HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Parkinson's disease Mathematical models |
topic_facet | HEALTH & FITNESS / Diseases / General MEDICAL / Clinical Medicine MEDICAL / Diseases MEDICAL / Evidence-Based Medicine MEDICAL / Internal Medicine Parkinson's disease Mathematical models |
url | https://www.sciencedirect.com/science/book/9780128146149 |
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