Target validation in drug discovery:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam ; Boston
Academic Press
2007
|
| Schlagworte: | |
| Beschreibung: | Print version record |
| Beschreibung: | 1 online resource (xii, 279 pages) illustrations |
| ISBN: | 9780123693938 0123693934 9780080465975 0080465978 |
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| 245 | 1 | 0 | |a Target validation in drug discovery |c editors, Brian W. Metcalf and Susan Dillon |
| 264 | 1 | |a Amsterdam ; Boston |b Academic Press |c 2007 | |
| 300 | |a 1 online resource (xii, 279 pages) |b illustrations | ||
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| 505 | 8 | |a This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book | |
| 650 | 4 | |a Drug Design | |
| 650 | 4 | |a Drug Delivery Systems | |
| 650 | 4 | |a Technology, Pharmaceutical | |
| 650 | 4 | |a Biopharmaceutics | |
| 650 | 4 | |a Medicaments / Developpement | |
| 650 | 4 | |a Medicaments / Essais cliniques | |
| 650 | 4 | |a Criblage a haut debit (Developpement des medicaments) | |
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| 650 | 7 | |a MEDICAL / Pharmacology |2 bisacsh | |
| 650 | 7 | |a MEDICAL / Pharmacy |2 bisacsh | |
| 650 | 7 | |a MEDICAL / Nursing / Pharmacology |2 bisacsh | |
| 650 | 7 | |a Drug development |2 fast | |
| 650 | 7 | |a Drugs / Testing |2 fast | |
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| contents | This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book |
| ctrlnum | (ZDB-4-ENC)ocn162130366 (OCoLC)162130366 (DE-599)BVBBV045341814 |
| dewey-full | 615/.19 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.19 |
| dewey-search | 615/.19 |
| dewey-sort | 3615 219 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| id | DE-604.BV045341814 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T08:15:25Z |
| institution | BVB |
| isbn | 9780123693938 0123693934 9780080465975 0080465978 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030728517 |
| oclc_num | 162130366 |
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| physical | 1 online resource (xii, 279 pages) illustrations |
| psigel | ZDB-4-ENC |
| publishDate | 2007 |
| publishDateSearch | 2007 |
| publishDateSort | 2007 |
| publisher | Academic Press |
| record_format | marc |
| spelling | Target validation in drug discovery editors, Brian W. Metcalf and Susan Dillon Amsterdam ; Boston Academic Press 2007 1 online resource (xii, 279 pages) illustrations txt rdacontent c rdamedia cr rdacarrier Print version record This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book Drug Design Drug Delivery Systems Technology, Pharmaceutical Biopharmaceutics Medicaments / Developpement Medicaments / Essais cliniques Criblage a haut debit (Developpement des medicaments) MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Drug development fast Drugs / Testing fast High throughput screening (Drug development) fast Medicaments / Mise au point ram Medicaments / Essais cliniques ram Criblage pharmacologique ram Drug development Drugs Testing High throughput screening (Drug development) Metcalf, Brian W. Sonstige oth Dillon, Susan 1952- Sonstige oth Erscheint auch als Druck-Ausgabe Target validation in drug discovery Amsterdam ; Boston : Academic Press, 2007 0123693934 9780123693938 |
| spellingShingle | Target validation in drug discovery This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book Drug Design Drug Delivery Systems Technology, Pharmaceutical Biopharmaceutics Medicaments / Developpement Medicaments / Essais cliniques Criblage a haut debit (Developpement des medicaments) MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Drug development fast Drugs / Testing fast High throughput screening (Drug development) fast Medicaments / Mise au point ram Medicaments / Essais cliniques ram Criblage pharmacologique ram Drug development Drugs Testing High throughput screening (Drug development) |
| title | Target validation in drug discovery |
| title_auth | Target validation in drug discovery |
| title_exact_search | Target validation in drug discovery |
| title_full | Target validation in drug discovery editors, Brian W. Metcalf and Susan Dillon |
| title_fullStr | Target validation in drug discovery editors, Brian W. Metcalf and Susan Dillon |
| title_full_unstemmed | Target validation in drug discovery editors, Brian W. Metcalf and Susan Dillon |
| title_short | Target validation in drug discovery |
| title_sort | target validation in drug discovery |
| topic | Drug Design Drug Delivery Systems Technology, Pharmaceutical Biopharmaceutics Medicaments / Developpement Medicaments / Essais cliniques Criblage a haut debit (Developpement des medicaments) MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Drug development fast Drugs / Testing fast High throughput screening (Drug development) fast Medicaments / Mise au point ram Medicaments / Essais cliniques ram Criblage pharmacologique ram Drug development Drugs Testing High throughput screening (Drug development) |
| topic_facet | Drug Design Drug Delivery Systems Technology, Pharmaceutical Biopharmaceutics Medicaments / Developpement Medicaments / Essais cliniques Criblage a haut debit (Developpement des medicaments) MEDICAL / Drug Guides MEDICAL / Pharmacology MEDICAL / Pharmacy MEDICAL / Nursing / Pharmacology Drug development Drugs / Testing High throughput screening (Drug development) Medicaments / Mise au point Criblage pharmacologique Drug development Drugs Testing High throughput screening (Drug development) |
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