This book provides coverage, methodology, and laboratory protocols on the more essential aspects of protein tyrosine phosphatase (PTP) function and regulation, including the use of standardized in vitro functional assays, suitable cell systems, and animal and microorganism models. Chapters covering...

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Bibliographic Details

Other Authors:	Pulido, Rafael (Editor)
Format:	Electronic eBook
Language:	English
Published:	New York, NY Springer New York 2016
Series:	Methods in Molecular Biology 1447
Subjects:	Life Sciences Protein Science Life sciences Proteins Proteintyrosinphosphatase In-vitro-Kultur Tiermodell Biochemie Hydrolasen Aufsatzsammlung
Online Access:	UBR01 TUM01 Volltext
Summary:	This book provides coverage, methodology, and laboratory protocols on the more essential aspects of protein tyrosine phosphatase (PTP) function and regulation, including the use of standardized in vitro functional assays, suitable cell systems, and animal and microorganism models. Chapters covering state-of-the-art technical approaches suitable to decipher the physiologic roles of PTPs, and their involvement in tissue-specific functions, are also included, which will be of utility for both newcomers and experienced researchers in the field of tyrosine- and phosphoinositide- phosphorylation/dephosphorylation. Written in the highly successful Methods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. < Authoritative and practical, Protein Tyrosine Phosphatases: Methods and Protocols aims to aid researchers in better defining the common and individual features of the PTP family members and translating this knowledge into PTP-based therapy for human disease
Physical Description:	1 Online-Ressource (XII, 402 p. 79 illus., 51 illus. in color)
ISBN:	9781493937462
DOI:	10.1007/978-1-4939-3746-2