G Protein-Coupled Receptor Screening Assays: Methods and Protocols
This volume explores the considerable efforts that have been directed towards the development of G Protein-Coupled Receptors (GPCR) screening assays in order to disclose GPCR acting compounds, elucidate signaling mechanisms or evaluate compound’s efficacy. New discoveries in the field, along with t...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2015
|
| Schriftenreihe: | Methods in Molecular Biology
1272 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | This volume explores the considerable efforts that have been directed towards the development of G Protein-Coupled Receptors (GPCR) screening assays in order to disclose GPCR acting compounds, elucidate signaling mechanisms or evaluate compound’s efficacy. New discoveries in the field, along with the widely recognized need for better and safer pharmaceutical drugs constitute the main motivation for this book. Readers, both beginners and experienced researchers, will receive an updated overview of not only the established, but also the innovative technologies that promise to advance GPCR drug research. This book is organized into two major parts: the introductory part discusses the necessary foundations for the understanding of GPCR action and the rationale behind the design of the available screening assays; and part two provides detailed protocols for different screening approaches. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Practical and innovative, G Protein-Coupled Receptor Screening Assays: Methods and Protocols reaches out to everyone involved in the discovery of GPCR-active drugs, and provides a transversal overview of the different levels of GPCR signaling addressable in the different screening strategies and presents practical examples of how current assay technologies are contributing to new paradigms in GPCR drug research |
| Beschreibung: | 1 Online-Ressource (XII, 296 p. 78 illus., 51 illus. in color) |
| ISBN: | 9781493923366 |
| DOI: | 10.1007/978-1-4939-2336-6 |
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Datensatz im Suchindex
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| spelling | G Protein-Coupled Receptor Screening Assays Methods and Protocols edited by Duarte Miguel F. Prazeres, Sofia Aires M. Martins New York, NY Springer New York 2015 1 Online-Ressource (XII, 296 p. 78 illus., 51 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1272 This volume explores the considerable efforts that have been directed towards the development of G Protein-Coupled Receptors (GPCR) screening assays in order to disclose GPCR acting compounds, elucidate signaling mechanisms or evaluate compound’s efficacy. New discoveries in the field, along with the widely recognized need for better and safer pharmaceutical drugs constitute the main motivation for this book. Readers, both beginners and experienced researchers, will receive an updated overview of not only the established, but also the innovative technologies that promise to advance GPCR drug research. This book is organized into two major parts: the introductory part discusses the necessary foundations for the understanding of GPCR action and the rationale behind the design of the available screening assays; and part two provides detailed protocols for different screening approaches. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Practical and innovative, G Protein-Coupled Receptor Screening Assays: Methods and Protocols reaches out to everyone involved in the discovery of GPCR-active drugs, and provides a transversal overview of the different levels of GPCR signaling addressable in the different screening strategies and presents practical examples of how current assay technologies are contributing to new paradigms in GPCR drug research Biomedicine Pharmacology/Toxicology Proteomics Medicine Pharmacology Biochemische Analyse (DE-588)4255721-5 gnd rswk-swf G-Protein gekoppelter Rezeptor (DE-588)7723480-7 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content G-Protein gekoppelter Rezeptor (DE-588)7723480-7 s Biochemische Analyse (DE-588)4255721-5 s b DE-604 Prazeres, Duarte Miguel F. edt Martins, Sofia Aires M. edt Erscheint auch als Druck-Ausgabe 9781493923359 https://doi.org/10.1007/978-1-4939-2336-6 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | G Protein-Coupled Receptor Screening Assays Methods and Protocols Biomedicine Pharmacology/Toxicology Proteomics Medicine Pharmacology Biochemische Analyse (DE-588)4255721-5 gnd G-Protein gekoppelter Rezeptor (DE-588)7723480-7 gnd |
| subject_GND | (DE-588)4255721-5 (DE-588)7723480-7 (DE-588)4143413-4 |
| title | G Protein-Coupled Receptor Screening Assays Methods and Protocols |
| title_auth | G Protein-Coupled Receptor Screening Assays Methods and Protocols |
| title_exact_search | G Protein-Coupled Receptor Screening Assays Methods and Protocols |
| title_full | G Protein-Coupled Receptor Screening Assays Methods and Protocols edited by Duarte Miguel F. Prazeres, Sofia Aires M. Martins |
| title_fullStr | G Protein-Coupled Receptor Screening Assays Methods and Protocols edited by Duarte Miguel F. Prazeres, Sofia Aires M. Martins |
| title_full_unstemmed | G Protein-Coupled Receptor Screening Assays Methods and Protocols edited by Duarte Miguel F. Prazeres, Sofia Aires M. Martins |
| title_short | G Protein-Coupled Receptor Screening Assays |
| title_sort | g protein coupled receptor screening assays methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Pharmacology/Toxicology Proteomics Medicine Pharmacology Biochemische Analyse (DE-588)4255721-5 gnd G-Protein gekoppelter Rezeptor (DE-588)7723480-7 gnd |
| topic_facet | Biomedicine Pharmacology/Toxicology Proteomics Medicine Pharmacology Biochemische Analyse G-Protein gekoppelter Rezeptor Aufsatzsammlung |
| url | https://doi.org/10.1007/978-1-4939-2336-6 |
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