Cyclin-Dependent Kinase (CDK) Inhibitors: Methods and Protocols
This volume contains a collection of relevant information for drug discovery in cell cycle research. Protocols to develop screening assays or to identify novel CDK inhibitors are discussed in the first part of the book. The second part of the book describes elaborate procedures to evaluate activity...
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| Other Authors: | , , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
2016
|
| Edition: | 1st ed. 2016 |
| Series: | Methods in Molecular Biology
1336 |
| Subjects: | |
| Online Access: | UBR01 TUM01 Volltext |
| Summary: | This volume contains a collection of relevant information for drug discovery in cell cycle research. Protocols to develop screening assays or to identify novel CDK inhibitors are discussed in the first part of the book. The second part of the book describes elaborate procedures to evaluate activity and mechanism of action of new and already identified CDK inhibitors. The third part of the book talks about protocols to evaluate metabolomics changes associated to inhibitor treatment. Drug delivery strategies focused on nanoparticle development to provide alternative internalization systems for increasing inhibitor efficacy are also described. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Cyclin-Dependent Kinase (CDK) Inhibitors: Methods and Protocols is a useful tool for scientists interested in this research field |
| Physical Description: | 1 Online-Ressource (X, 227 p. 42 illus., 22 illus. in color) |
| ISBN: | 9781493929269 |
| DOI: | 10.1007/978-1-4939-2926-9 |
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| spelling | Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols edited by Mar Orzáez, Mónica Sancho Medina, Enrique Pérez-Payá 1st ed. 2016 New York, NY Springer New York 2016 1 Online-Ressource (X, 227 p. 42 illus., 22 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1336 This volume contains a collection of relevant information for drug discovery in cell cycle research. Protocols to develop screening assays or to identify novel CDK inhibitors are discussed in the first part of the book. The second part of the book describes elaborate procedures to evaluate activity and mechanism of action of new and already identified CDK inhibitors. The third part of the book talks about protocols to evaluate metabolomics changes associated to inhibitor treatment. Drug delivery strategies focused on nanoparticle development to provide alternative internalization systems for increasing inhibitor efficacy are also described. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Cyclin-Dependent Kinase (CDK) Inhibitors: Methods and Protocols is a useful tool for scientists interested in this research field Biomedicine Pharmacology/Toxicology Medicine Pharmacology Orzáez, Mar edt Sancho Medina, Mónica edt Pérez-Payá, Enrique edt Erscheint auch als Druck-Ausgabe 9781493929252 https://doi.org/10.1007/978-1-4939-2926-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
| title | Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols |
| title_auth | Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols |
| title_exact_search | Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols |
| title_full | Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols edited by Mar Orzáez, Mónica Sancho Medina, Enrique Pérez-Payá |
| title_fullStr | Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols edited by Mar Orzáez, Mónica Sancho Medina, Enrique Pérez-Payá |
| title_full_unstemmed | Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols edited by Mar Orzáez, Mónica Sancho Medina, Enrique Pérez-Payá |
| title_short | Cyclin-Dependent Kinase (CDK) Inhibitors |
| title_sort | cyclin dependent kinase cdk inhibitors methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
| topic_facet | Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
| url | https://doi.org/10.1007/978-1-4939-2926-9 |
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