Macromolecular Crystallography Protocols: Volume 1, Preparation and Crystallization of Macromolecules

Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1, Preparation and Crystallization of Macromolecules and Volume 2, Structure Determination, explore recent advance...

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Bibliographic Details
Other Authors: Walker, John M. (Editor), Doublié, Sylvie (Editor)
Format: Electronic eBook
Language:English
Published: Totowa, NJ Humana Press 2007
Series:Methods in Molecular Biology 363
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Online Access:UBR01
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Summary:Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1, Preparation and Crystallization of Macromolecules and Volume 2, Structure Determination, explore recent advances that have accelerated the pace of structural determination and made crystallography accessible to a broader range of investigators. Volume 1 is composed of detailed protocols for the preparation and optimization of crystals, including tips from the experts on the best methods for inducing proteins to adopt their crystalline form. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization, as well as computational techniques for data collection, phasing, and refinement. The volume concludes with a detailed and insightful survey of available crystallographic software. These volumes will be an indispensable reference for obtaining macromolecular crystals and determining their three-dimensional structure
Physical Description:1 Online-Ressource (XIV, 280 p. 49 illus)
ISBN:9781597452090
DOI:10.1007/978-1-59745-209-0

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