The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify...

Full description

Bibliographic Details

Other Authors:	Moll, Jurgen (Editor), Colombo, Riccardo (Editor)
Format:	Electronic eBook
Language:	English
Published:	Totowa, NJ Humana Press 2013
Series:	Methods in Molecular Biology, Methods and Protocols 986
Subjects:	Biomedicine Pharmacology/Toxicology Medicinal Chemistry Medicine Pharmacology Medicinal chemistry
Online Access:	UBR01 TUM01 Volltext
Summary:	The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify and validate new target. These include methods and approaches covering biochemical, cell based, in vivo models and translational methods. Chapters also include selected case reports that demonstrate the integration of these technologies to real life experiences and to demonstrate the multiple use of more than one technology to increase knowledge on a specific target. These Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.   Thorough and intuitive, Target Identification and Validation in Drug Discovery: Methods and Protocols contains a comprehensive list of essential methods and clear protocols to follow
Physical Description:	1 Online-Ressource (XV, 371 p. 62 illus., 19 illus. in color)
ISBN:	9781627033114
DOI:	10.1007/978-1-62703-311-4