Target Identification and Validation in Drug Discovery: Methods and Protocols
The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2013
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
986 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify and validate new target. These include methods and approaches covering biochemical, cell based, in vivo models and translational methods. Chapters also include selected case reports that demonstrate the integration of these technologies to real life experiences and to demonstrate the multiple use of more than one technology to increase knowledge on a specific target. These Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Target Identification and Validation in Drug Discovery: Methods and Protocols contains a comprehensive list of essential methods and clear protocols to follow |
| Beschreibung: | 1 Online-Ressource (XV, 371 p. 62 illus., 19 illus. in color) |
| ISBN: | 9781627033114 |
| DOI: | 10.1007/978-1-62703-311-4 |
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| 520 | |a The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify and validate new target. These include methods and approaches covering biochemical, cell based, in vivo models and translational methods. Chapters also include selected case reports that demonstrate the integration of these technologies to real life experiences and to demonstrate the multiple use of more than one technology to increase knowledge on a specific target. These Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Target Identification and Validation in Drug Discovery: Methods and Protocols contains a comprehensive list of essential methods and clear protocols to follow | ||
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| dewey-ones | 615 - Pharmacology and therapeutics |
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| dewey-search | 615 |
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| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
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| spelling | Target Identification and Validation in Drug Discovery Methods and Protocols edited by Jurgen Moll, Riccardo Colombo Totowa, NJ Humana Press 2013 1 Online-Ressource (XV, 371 p. 62 illus., 19 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 986 The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify and validate new target. These include methods and approaches covering biochemical, cell based, in vivo models and translational methods. Chapters also include selected case reports that demonstrate the integration of these technologies to real life experiences and to demonstrate the multiple use of more than one technology to increase knowledge on a specific target. These Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Target Identification and Validation in Drug Discovery: Methods and Protocols contains a comprehensive list of essential methods and clear protocols to follow Biomedicine Pharmacology/Toxicology Medicinal Chemistry Medicine Pharmacology Medicinal chemistry Moll, Jurgen edt Colombo, Riccardo edt Erscheint auch als Druck-Ausgabe 9781627033107 https://doi.org/10.1007/978-1-62703-311-4 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Target Identification and Validation in Drug Discovery Methods and Protocols Biomedicine Pharmacology/Toxicology Medicinal Chemistry Medicine Pharmacology Medicinal chemistry |
| title | Target Identification and Validation in Drug Discovery Methods and Protocols |
| title_auth | Target Identification and Validation in Drug Discovery Methods and Protocols |
| title_exact_search | Target Identification and Validation in Drug Discovery Methods and Protocols |
| title_full | Target Identification and Validation in Drug Discovery Methods and Protocols edited by Jurgen Moll, Riccardo Colombo |
| title_fullStr | Target Identification and Validation in Drug Discovery Methods and Protocols edited by Jurgen Moll, Riccardo Colombo |
| title_full_unstemmed | Target Identification and Validation in Drug Discovery Methods and Protocols edited by Jurgen Moll, Riccardo Colombo |
| title_short | Target Identification and Validation in Drug Discovery |
| title_sort | target identification and validation in drug discovery methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Pharmacology/Toxicology Medicinal Chemistry Medicine Pharmacology Medicinal chemistry |
| topic_facet | Biomedicine Pharmacology/Toxicology Medicinal Chemistry Medicine Pharmacology Medicinal chemistry |
| url | https://doi.org/10.1007/978-1-62703-311-4 |
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