Chemogenomics: Methods and Applications
The establishment, analysis, prediction, and expansion of a comprehensive ligand-target Structure-Activity Relationship (SAR) in the post-genomic era presents a key research challenge for this century. In Chemogenomics: Methods and Applications, experts from academia and industry explore cutting-edg...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2009
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
575 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | The establishment, analysis, prediction, and expansion of a comprehensive ligand-target Structure-Activity Relationship (SAR) in the post-genomic era presents a key research challenge for this century. In Chemogenomics: Methods and Applications, experts from academia and industry explore cutting-edge in vitro and in silico approaches available today and outline the relevant aspects of chemistry, biology, and molecular informatics which are the cornerstones of chemogenomics, thus combining introductory concepts with detailed methods and protocols. Covering topics such as target family-oriented compound library design, drug discovery targeting the purinome and co-factor binding sites, as well as the pocketome engine and molecular interaction field approaches, the book emphasizes systemization as an advantage to furthering the difficult science of drug discovery. As a volume in the highly successful Methods in Molecular Biology™ series format, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and practical, Chemogenomics: Methods and Applications presents content which will be of enormous value to those striving for the discovery of new and better therapies for diseases |
| Beschreibung: | 1 Online-Ressource (X, 320 p. 107 illus) |
| ISBN: | 9781607612742 |
| DOI: | 10.1007/978-1-60761-274-2 |
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| spelling | Chemogenomics Methods and Applications edited by Edgar Jacoby Totowa, NJ Humana Press 2009 1 Online-Ressource (X, 320 p. 107 illus) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 575 The establishment, analysis, prediction, and expansion of a comprehensive ligand-target Structure-Activity Relationship (SAR) in the post-genomic era presents a key research challenge for this century. In Chemogenomics: Methods and Applications, experts from academia and industry explore cutting-edge in vitro and in silico approaches available today and outline the relevant aspects of chemistry, biology, and molecular informatics which are the cornerstones of chemogenomics, thus combining introductory concepts with detailed methods and protocols. Covering topics such as target family-oriented compound library design, drug discovery targeting the purinome and co-factor binding sites, as well as the pocketome engine and molecular interaction field approaches, the book emphasizes systemization as an advantage to furthering the difficult science of drug discovery. As a volume in the highly successful Methods in Molecular Biology™ series format, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and practical, Chemogenomics: Methods and Applications presents content which will be of enormous value to those striving for the discovery of new and better therapies for diseases Life Sciences Biochemistry, general Human Genetics Analytical Chemistry Combinatorial Libraries Life sciences Human genetics Analytical chemistry Biochemistry Combinatorial chemistry Chemische Genetik (DE-588)7688784-4 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Chemische Genetik (DE-588)7688784-4 s 2\p DE-604 Jacoby, Edgar edt Erscheint auch als Druck-Ausgabe 9781607612735 https://doi.org/10.1007/978-1-60761-274-2 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Chemogenomics Methods and Applications Life Sciences Biochemistry, general Human Genetics Analytical Chemistry Combinatorial Libraries Life sciences Human genetics Analytical chemistry Biochemistry Combinatorial chemistry Chemische Genetik (DE-588)7688784-4 gnd |
| subject_GND | (DE-588)7688784-4 (DE-588)4143413-4 |
| title | Chemogenomics Methods and Applications |
| title_auth | Chemogenomics Methods and Applications |
| title_exact_search | Chemogenomics Methods and Applications |
| title_full | Chemogenomics Methods and Applications edited by Edgar Jacoby |
| title_fullStr | Chemogenomics Methods and Applications edited by Edgar Jacoby |
| title_full_unstemmed | Chemogenomics Methods and Applications edited by Edgar Jacoby |
| title_short | Chemogenomics |
| title_sort | chemogenomics methods and applications |
| title_sub | Methods and Applications |
| topic | Life Sciences Biochemistry, general Human Genetics Analytical Chemistry Combinatorial Libraries Life sciences Human genetics Analytical chemistry Biochemistry Combinatorial chemistry Chemische Genetik (DE-588)7688784-4 gnd |
| topic_facet | Life Sciences Biochemistry, general Human Genetics Analytical Chemistry Combinatorial Libraries Life sciences Human genetics Analytical chemistry Biochemistry Combinatorial chemistry Chemische Genetik Aufsatzsammlung |
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