Protein Kinase Protocols:
As key components of many cell signaling pathways, protein kinases are implicated in a broad variety of diseases, including cancers and neurodegenerative conditions, and offer considerable potential as tractable targets for therapeutic intervention. In Protein Kinase Protocols, a panel of highly ski...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2001
|
| Schriftenreihe: | Methods in Molecular Biology™
124 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | As key components of many cell signaling pathways, protein kinases are implicated in a broad variety of diseases, including cancers and neurodegenerative conditions, and offer considerable potential as tractable targets for therapeutic intervention. In Protein Kinase Protocols, a panel of highly skilled laboratory investigators describe both basic and more sophisticated methods for the analysis of kinase-mediated signaling cascades, with emphasis on the identification of proteins according to their interactive relationships and the analysis of their functional properties. Described in step-by-step detail, these readily reproducible techniques offer novices quick access to a complicated field, and provide more experienced investigators many novel time-saving ploys. Emphasis is given to the critical technical steps that are often omitted from methods published in the primary literature. There are also tips on potential pitfalls and copious notes on how to adjust the protocols to work in related systems. Broad in its range of techniques and thoroughly detailed to help ensure experimental success, Protein Kinase Protocols offers both novice and experienced investigators powerful tools for understanding the functional roles of specific protein kinases within signaling cascades and for identification and evaluation of novel therapeutic targets |
| Beschreibung: | 1 Online-Ressource (XIII, 365 p) |
| ISBN: | 9781592590599 |
| DOI: | 10.1385/1592590594 |
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| 520 | |a As key components of many cell signaling pathways, protein kinases are implicated in a broad variety of diseases, including cancers and neurodegenerative conditions, and offer considerable potential as tractable targets for therapeutic intervention. In Protein Kinase Protocols, a panel of highly skilled laboratory investigators describe both basic and more sophisticated methods for the analysis of kinase-mediated signaling cascades, with emphasis on the identification of proteins according to their interactive relationships and the analysis of their functional properties. Described in step-by-step detail, these readily reproducible techniques offer novices quick access to a complicated field, and provide more experienced investigators many novel time-saving ploys. Emphasis is given to the critical technical steps that are often omitted from methods published in the primary literature. There are also tips on potential pitfalls and copious notes on how to adjust the protocols to work in related systems. Broad in its range of techniques and thoroughly detailed to help ensure experimental success, Protein Kinase Protocols offers both novice and experienced investigators powerful tools for understanding the functional roles of specific protein kinases within signaling cascades and for identification and evaluation of novel therapeutic targets | ||
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| id | DE-604.BV044952213 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:05:37Z |
| institution | BVB |
| isbn | 9781592590599 |
| language | English |
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| physical | 1 Online-Ressource (XIII, 365 p) |
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| spelling | Protein Kinase Protocols edited by Alastair D. Reith Totowa, NJ Humana Press 2001 1 Online-Ressource (XIII, 365 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 124 As key components of many cell signaling pathways, protein kinases are implicated in a broad variety of diseases, including cancers and neurodegenerative conditions, and offer considerable potential as tractable targets for therapeutic intervention. In Protein Kinase Protocols, a panel of highly skilled laboratory investigators describe both basic and more sophisticated methods for the analysis of kinase-mediated signaling cascades, with emphasis on the identification of proteins according to their interactive relationships and the analysis of their functional properties. Described in step-by-step detail, these readily reproducible techniques offer novices quick access to a complicated field, and provide more experienced investigators many novel time-saving ploys. Emphasis is given to the critical technical steps that are often omitted from methods published in the primary literature. There are also tips on potential pitfalls and copious notes on how to adjust the protocols to work in related systems. Broad in its range of techniques and thoroughly detailed to help ensure experimental success, Protein Kinase Protocols offers both novice and experienced investigators powerful tools for understanding the functional roles of specific protein kinases within signaling cascades and for identification and evaluation of novel therapeutic targets Life Sciences Biochemistry, general Life sciences Biochemistry Proteinkinasen (DE-588)4175996-5 gnd rswk-swf Biochemische Methode (DE-588)4319880-6 gnd rswk-swf Proteinkinasen (DE-588)4175996-5 s Biochemische Methode (DE-588)4319880-6 s DE-604 Reith, Alastair D. edt Erscheint auch als Druck-Ausgabe 9780896037007 https://doi.org/10.1385/1592590594 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Protein Kinase Protocols Life Sciences Biochemistry, general Life sciences Biochemistry Proteinkinasen (DE-588)4175996-5 gnd Biochemische Methode (DE-588)4319880-6 gnd |
| subject_GND | (DE-588)4175996-5 (DE-588)4319880-6 |
| title | Protein Kinase Protocols |
| title_auth | Protein Kinase Protocols |
| title_exact_search | Protein Kinase Protocols |
| title_full | Protein Kinase Protocols edited by Alastair D. Reith |
| title_fullStr | Protein Kinase Protocols edited by Alastair D. Reith |
| title_full_unstemmed | Protein Kinase Protocols edited by Alastair D. Reith |
| title_short | Protein Kinase Protocols |
| title_sort | protein kinase protocols |
| topic | Life Sciences Biochemistry, general Life sciences Biochemistry Proteinkinasen (DE-588)4175996-5 gnd Biochemische Methode (DE-588)4319880-6 gnd |
| topic_facet | Life Sciences Biochemistry, general Life sciences Biochemistry Proteinkinasen Biochemische Methode |
| url | https://doi.org/10.1385/1592590594 |
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