Fast Detection of DNA Damage: Methods and Protocols

This volume presents a comprehensive collection of quick assays for the detection of nuclear and mitochondrial DNA damage and its effects in live and fixed cells and tissues, and in bacterial genomes. Although, such rapid techniques are in demand in the "research trenches" they are not cov...

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Bibliographic Details
Other Authors: Didenko, Vladimir V. (Editor)
Format: Electronic eBook
Language:English
Published: New York, NY Springer New York 2017
Series:Methods in Molecular Biology 1644
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Online Access:UBR01
TUM01
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Summary:This volume presents a comprehensive collection of quick assays for the detection of nuclear and mitochondrial DNA damage and its effects in live and fixed cells and tissues, and in bacterial genomes. Although, such rapid techniques are in demand in the "research trenches" they are not covered well in the literature. This volume is the first such compendium of the time-saving techniques for detection of DNA damage and its direct physiological outcomes including apoptosis, necrosis and phagocytic clearance. The volume demonstrates all levels of detection, starting from the molecular level up to the level of the entire live organism. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Fast Detection of DNA Damage: Methods and Protocols aims to provide easily reproducible techniques requiring only few steps to perform
Physical Description:1 Online-Ressource (X, 216 p. 42 illus., 24 illus. in color)
ISBN:9781493971879
DOI:10.1007/978-1-4939-7187-9

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