Protein Folding, Misfolding, and Disease: Methods and Protocols
Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of prot...
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| Other Authors: | , , , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2011
|
| Series: | Methods in Molecular Biology, Methods and Protocols
752 |
| Subjects: | |
| Online Access: | UBR01 TUM01 Volltext |
| Summary: | Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field |
| Physical Description: | 1 Online-Ressource (X, 230 p. 50 illus) |
| ISBN: | 9781603272230 |
| DOI: | 10.1007/978-1-60327-223-0 |
Staff View
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| series2 | Methods in Molecular Biology, Methods and Protocols |
| spelling | Protein Folding, Misfolding, and Disease Methods and Protocols edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai Totowa, NJ Humana Press 2011 1 Online-Ressource (X, 230 p. 50 illus) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 752 Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of –the-art technologies. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field Life Sciences Protein Science Pathology Life sciences Proteins Konformationsänderung (DE-588)4164966-7 gnd rswk-swf Proteinfaltung (DE-588)4324567-5 gnd rswk-swf Labortechnik (DE-588)4123602-6 gnd rswk-swf Pathophysiologie (DE-588)4044898-8 gnd rswk-swf Proteinfaltung (DE-588)4324567-5 s Konformationsänderung (DE-588)4164966-7 s Pathophysiologie (DE-588)4044898-8 s DE-604 Labortechnik (DE-588)4123602-6 s b DE-604 Hill, Andrew F. edt Barnham, Kevin J. edt Bottomley, Stephen P. edt Cappai, Roberto edt Erscheint auch als Druck-Ausgabe 9781603272216 https://doi.org/10.1007/978-1-60327-223-0 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Protein Folding, Misfolding, and Disease Methods and Protocols Life Sciences Protein Science Pathology Life sciences Proteins Konformationsänderung (DE-588)4164966-7 gnd Proteinfaltung (DE-588)4324567-5 gnd Labortechnik (DE-588)4123602-6 gnd Pathophysiologie (DE-588)4044898-8 gnd |
| subject_GND | (DE-588)4164966-7 (DE-588)4324567-5 (DE-588)4123602-6 (DE-588)4044898-8 |
| title | Protein Folding, Misfolding, and Disease Methods and Protocols |
| title_auth | Protein Folding, Misfolding, and Disease Methods and Protocols |
| title_exact_search | Protein Folding, Misfolding, and Disease Methods and Protocols |
| title_full | Protein Folding, Misfolding, and Disease Methods and Protocols edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai |
| title_fullStr | Protein Folding, Misfolding, and Disease Methods and Protocols edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai |
| title_full_unstemmed | Protein Folding, Misfolding, and Disease Methods and Protocols edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai |
| title_short | Protein Folding, Misfolding, and Disease |
| title_sort | protein folding misfolding and disease methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Protein Science Pathology Life sciences Proteins Konformationsänderung (DE-588)4164966-7 gnd Proteinfaltung (DE-588)4324567-5 gnd Labortechnik (DE-588)4123602-6 gnd Pathophysiologie (DE-588)4044898-8 gnd |
| topic_facet | Life Sciences Protein Science Pathology Life sciences Proteins Konformationsänderung Proteinfaltung Labortechnik Pathophysiologie |
| url | https://doi.org/10.1007/978-1-60327-223-0 |
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