Cell-Based Assays for High-Throughput Screening: Methods and Protocols

As the use of high-throughput screening expands and creates more interest in the academic community, the need for detailed reference materials becomes ever more pressing. Cell-Based Assays for High-Throughput Screening: Methods and Protocols aims to fill an important part of this need by providing a...

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Bibliographic Details
Other Authors: Clemons, Paul A. (Editor), Tolliday, Nicola J. (Editor), Wagner, Bridget K. (Editor)
Format: Electronic eBook
Language:English
Published: Totowa, NJ Humana Press 2009
Series:Methods in Molecular Biology, Methods and Protocols 486
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Online Access:UBR01
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Summary:As the use of high-throughput screening expands and creates more interest in the academic community, the need for detailed reference materials becomes ever more pressing. Cell-Based Assays for High-Throughput Screening: Methods and Protocols aims to fill an important part of this need by providing an easily accessible reference volume for cell-based phenotypic screening. Leading researchers in the field contribute state-of-the-art methods with actionable protocols covering four major areas of study: model biological systems, screening modalities and assay systems, detection technologies, and approaches to data analysis. Written in the highly successful Methods in Molecular Biology™ series format, each chapter includes a brief introduction to the subject, lists of necessary materials and reagents, step-by-step laboratory protocols, and a Notes section detailing tips on troubleshooting and avoiding known pitfalls. Cutting-edge and easy-to-use, Cell-Based Assays for High-Throughput Screening: Methods and Protocols presents an overview of relevant approaches, enabling the direct application of existing methods to new discoveries while also inspiring researchers to approach their screening projects in a conceptually modular fashion, enhancing the power to discover through new combinations of existing approaches
Physical Description:1 Online-Ressource (X, 218 p)
ISBN:9781603275453
DOI:10.1007/978-1-60327-545-3

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