MicroRNA Protocols:
It is now known that microRNA (miRNA), once thought to be junk, can suppress the expression of other genes and may be involved in numerous cellular processes, including cell proliferation, apoptosis, cell differentiation, and development. In MicroRNA Protocols, expert miRNA researchers explain its b...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2006
|
| Schriftenreihe: | Methods in Molecular Biology™
342 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | It is now known that microRNA (miRNA), once thought to be junk, can suppress the expression of other genes and may be involved in numerous cellular processes, including cell proliferation, apoptosis, cell differentiation, and development. In MicroRNA Protocols, expert miRNA researchers explain its basic concepts and introduce the most advanced technologies and techniques for predicting screening, isolating, and assaying it. The authors provide diverse, novel, and useful descriptions of miRNAs in several species-including plants, worms, flies, fish, chicks, mice, and humans-and show how they have been employed to develop miRNA as a potential drug design tool. Highlights include miRNA and their target prediction by computer analysis, functional assays of miRNA in vitro and in vivo, and transgenic animal models using miRNA technologies. Additional chapters cover gene regulation, small RNA function, RNA interference mechanisms, and transgenetics. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Eminently practical and cutting-edge, MicroRNA Protocols affords biomedical researchers readily reproducible techniques to understand and study the molecular pathogenesis of disease and design new therapeutic strategies |
| Beschreibung: | 1 Online-Ressource (XIV, 366 p. 83 illus., 3 illus. in color) |
| ISBN: | 9781597451239 |
| DOI: | 10.1385/1597451231 |
Internformat
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| 520 | |a It is now known that microRNA (miRNA), once thought to be junk, can suppress the expression of other genes and may be involved in numerous cellular processes, including cell proliferation, apoptosis, cell differentiation, and development. In MicroRNA Protocols, expert miRNA researchers explain its basic concepts and introduce the most advanced technologies and techniques for predicting screening, isolating, and assaying it. The authors provide diverse, novel, and useful descriptions of miRNAs in several species-including plants, worms, flies, fish, chicks, mice, and humans-and show how they have been employed to develop miRNA as a potential drug design tool. Highlights include miRNA and their target prediction by computer analysis, functional assays of miRNA in vitro and in vivo, and transgenic animal models using miRNA technologies. Additional chapters cover gene regulation, small RNA function, RNA interference mechanisms, and transgenetics. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Eminently practical and cutting-edge, MicroRNA Protocols affords biomedical researchers readily reproducible techniques to understand and study the molecular pathogenesis of disease and design new therapeutic strategies | ||
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| spelling | MicroRNA Protocols edited by Shao-Yao Ying Totowa, NJ Humana Press 2006 1 Online-Ressource (XIV, 366 p. 83 illus., 3 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 342 It is now known that microRNA (miRNA), once thought to be junk, can suppress the expression of other genes and may be involved in numerous cellular processes, including cell proliferation, apoptosis, cell differentiation, and development. In MicroRNA Protocols, expert miRNA researchers explain its basic concepts and introduce the most advanced technologies and techniques for predicting screening, isolating, and assaying it. The authors provide diverse, novel, and useful descriptions of miRNAs in several species-including plants, worms, flies, fish, chicks, mice, and humans-and show how they have been employed to develop miRNA as a potential drug design tool. Highlights include miRNA and their target prediction by computer analysis, functional assays of miRNA in vitro and in vivo, and transgenic animal models using miRNA technologies. Additional chapters cover gene regulation, small RNA function, RNA interference mechanisms, and transgenetics. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Eminently practical and cutting-edge, MicroRNA Protocols affords biomedical researchers readily reproducible techniques to understand and study the molecular pathogenesis of disease and design new therapeutic strategies Life Sciences Cell Biology Life sciences Cell biology Niedermolekulare RNS (DE-588)4171858-6 gnd rswk-swf Labortechnik (DE-588)4123602-6 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Niedermolekulare RNS (DE-588)4171858-6 s Labortechnik (DE-588)4123602-6 s b DE-604 Ying, Shao-Yao edt Erscheint auch als Druck-Ausgabe 9781588295811 https://doi.org/10.1385/1597451231 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | MicroRNA Protocols Life Sciences Cell Biology Life sciences Cell biology Niedermolekulare RNS (DE-588)4171858-6 gnd Labortechnik (DE-588)4123602-6 gnd |
| subject_GND | (DE-588)4171858-6 (DE-588)4123602-6 (DE-588)4143413-4 |
| title | MicroRNA Protocols |
| title_auth | MicroRNA Protocols |
| title_exact_search | MicroRNA Protocols |
| title_full | MicroRNA Protocols edited by Shao-Yao Ying |
| title_fullStr | MicroRNA Protocols edited by Shao-Yao Ying |
| title_full_unstemmed | MicroRNA Protocols edited by Shao-Yao Ying |
| title_short | MicroRNA Protocols |
| title_sort | microrna protocols |
| topic | Life Sciences Cell Biology Life sciences Cell biology Niedermolekulare RNS (DE-588)4171858-6 gnd Labortechnik (DE-588)4123602-6 gnd |
| topic_facet | Life Sciences Cell Biology Life sciences Cell biology Niedermolekulare RNS Labortechnik Aufsatzsammlung |
| url | https://doi.org/10.1385/1597451231 |
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