Transgenic Mouse: Methods and Protocols
Genetically very similar to the human species, mice play an important role in biomedical research and have served as experimental models for a wide variety of pathologies, including cancer, cardiovascular diseases, and behavioral disorders. In Transgenic Mouse Methods and Protocols, Marten Hofker an...
Saved in:
| Other Authors: | , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2002
|
| Series: | Methods in Molecular Biology™
209 |
| Subjects: | |
| Online Access: | UBR01 TUM01 Volltext |
| Summary: | Genetically very similar to the human species, mice play an important role in biomedical research and have served as experimental models for a wide variety of pathologies, including cancer, cardiovascular diseases, and behavioral disorders. In Transgenic Mouse Methods and Protocols, Marten Hofker and Jan van Deursen have assembled a multidisciplinary collection of readily reproducible methods for working with mice, and particularly for generating mouse models that will enable us to better understand gene function. Described in step-by-step detail by highly experienced investigators, these proven techniques include new methods for conditional, induced knockout, and transgenic mice, as well as for working with mice in such important research areas as immunology, cancer, and atherosclerosis. Such alternative strategies as random mutagenesis and viral gene transduction for studying gene function in the mouse are also presented. Care is taken to make clear the details of the available approaches, as well as their limitations. Up-to-date and highly practical, Transgenic Mouse Methods and Protocols demonstrates clearly for both novice and expert investigators how to make novel transgenic mouse models, and how to use them effectively to understand the role of gene function in human health and disease |
| Physical Description: | 1 Online-Ressource (392 p. 80 illus., 4 illus. in color) |
| ISBN: | 9781592593408 |
| DOI: | 10.1385/1592593402 |
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| spelling | Transgenic Mouse Methods and Protocols edited by Marten H. Hofker, Jan van Deursen Totowa, NJ Humana Press 2002 1 Online-Ressource (392 p. 80 illus., 4 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 209 Genetically very similar to the human species, mice play an important role in biomedical research and have served as experimental models for a wide variety of pathologies, including cancer, cardiovascular diseases, and behavioral disorders. In Transgenic Mouse Methods and Protocols, Marten Hofker and Jan van Deursen have assembled a multidisciplinary collection of readily reproducible methods for working with mice, and particularly for generating mouse models that will enable us to better understand gene function. Described in step-by-step detail by highly experienced investigators, these proven techniques include new methods for conditional, induced knockout, and transgenic mice, as well as for working with mice in such important research areas as immunology, cancer, and atherosclerosis. Such alternative strategies as random mutagenesis and viral gene transduction for studying gene function in the mouse are also presented. Care is taken to make clear the details of the available approaches, as well as their limitations. Up-to-date and highly practical, Transgenic Mouse Methods and Protocols demonstrates clearly for both novice and expert investigators how to make novel transgenic mouse models, and how to use them effectively to understand the role of gene function in human health and disease Life Sciences Cell Biology Life sciences Cell biology Maus (DE-588)4169148-9 gnd rswk-swf Transgene Tiere (DE-588)4279021-9 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Maus (DE-588)4169148-9 s Transgene Tiere (DE-588)4279021-9 s DE-604 Hofker, Marten H. edt Deursen, Jan van edt Erscheint auch als Druck-Ausgabe 9780896039155 https://doi.org/10.1385/1592593402 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Transgenic Mouse Methods and Protocols Life Sciences Cell Biology Life sciences Cell biology Maus (DE-588)4169148-9 gnd Transgene Tiere (DE-588)4279021-9 gnd |
| subject_GND | (DE-588)4169148-9 (DE-588)4279021-9 (DE-588)4143413-4 |
| title | Transgenic Mouse Methods and Protocols |
| title_auth | Transgenic Mouse Methods and Protocols |
| title_exact_search | Transgenic Mouse Methods and Protocols |
| title_full | Transgenic Mouse Methods and Protocols edited by Marten H. Hofker, Jan van Deursen |
| title_fullStr | Transgenic Mouse Methods and Protocols edited by Marten H. Hofker, Jan van Deursen |
| title_full_unstemmed | Transgenic Mouse Methods and Protocols edited by Marten H. Hofker, Jan van Deursen |
| title_short | Transgenic Mouse |
| title_sort | transgenic mouse methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Cell Biology Life sciences Cell biology Maus (DE-588)4169148-9 gnd Transgene Tiere (DE-588)4279021-9 gnd |
| topic_facet | Life Sciences Cell Biology Life sciences Cell biology Maus Transgene Tiere Aufsatzsammlung |
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