Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of...

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Bibliographic Details

Other Authors:	Uversky, Vladimir N. (Editor), Dunker, A. Keith (Editor)
Format:	Electronic eBook
Language:	English
Published:	New York, NY Springer New York 2012
Series:	Methods in Molecular Biology, Methods and Protocols 896
Subjects:	Life Sciences Protein Science Protein Structure Life sciences Proteins
Online Access:	UBR01 TUM01 Volltext
Summary:	Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of ordered protein regions. In Intrinsically Disordered Protein Analysis: Methods and Experimental Tools, expert researchers explore the high abundance of IDPs in various organisms, their unique structural features, numerous functions, and crucial associations with different diseases. Volume 2 includes sections on single molecule techniques, methods to assess protein size and shape, analyzing conformational behavior, mass-spectrometry, expression and purification of IDP’s. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Intrinsically Disordered Protein Analysis: Methods and Experimental Tools helps scientists further their investigations of these fascinating and dynamic molecules
Physical Description:	1 Online-Ressource (XIV, 454 p. 85 illus., 30 illus. in color)
ISBN:	9781461437048
DOI:	10.1007/978-1-4614-3704-8