Steroid Receptor Methods: Protocols and Assays
Research into steroid receptor biology holds great promise for the treatment of cancer and endocrine disorders and for elucidating the fundamental biological mechanisms of gene expression. In Steroid Receptor Methods: Protocols and Assays, a distinguished team of principal investigators and their as...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2001
|
| Schriftenreihe: | Methods in Molecular Biology™
176 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Research into steroid receptor biology holds great promise for the treatment of cancer and endocrine disorders and for elucidating the fundamental biological mechanisms of gene expression. In Steroid Receptor Methods: Protocols and Assays, a distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA-binding characteristics and hormone-binding assays and with the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness. Finally, a discussion by example presents the most current bioinformatics tools and analytical techniques. Timely and highly accessible, Steroid Receptor Methods: Protocols and Assays provides biochemists and molecular biologists studying endocrine systems with a full range of the powerful tools needed for elucidating protein interactions with receptors and DNA, as well as for drug discovery |
| Beschreibung: | 1 Online-Ressource (XIV, 381 p) |
| ISBN: | 9781592591152 |
| DOI: | 10.1385/1592591159 |
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| spelling | Steroid Receptor Methods Protocols and Assays edited by Benjamin A. Lieberman Totowa, NJ Humana Press 2001 1 Online-Ressource (XIV, 381 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 176 Research into steroid receptor biology holds great promise for the treatment of cancer and endocrine disorders and for elucidating the fundamental biological mechanisms of gene expression. In Steroid Receptor Methods: Protocols and Assays, a distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA-binding characteristics and hormone-binding assays and with the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness. Finally, a discussion by example presents the most current bioinformatics tools and analytical techniques. Timely and highly accessible, Steroid Receptor Methods: Protocols and Assays provides biochemists and molecular biologists studying endocrine systems with a full range of the powerful tools needed for elucidating protein interactions with receptors and DNA, as well as for drug discovery Life Sciences Biochemistry, general Life sciences Biochemistry Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Steroidhormonrezeptor (DE-588)4057381-3 gnd rswk-swf Methode (DE-588)4038971-6 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Steroidhormonrezeptor (DE-588)4057381-3 s Molekularbiologie (DE-588)4039983-7 s Methode (DE-588)4038971-6 s DE-604 Lieberman, Benjamin A. edt Erscheint auch als Druck-Ausgabe 9780896037540 https://doi.org/10.1385/1592591159 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Steroid Receptor Methods Protocols and Assays Life Sciences Biochemistry, general Life sciences Biochemistry Molekularbiologie (DE-588)4039983-7 gnd Steroidhormonrezeptor (DE-588)4057381-3 gnd Methode (DE-588)4038971-6 gnd |
| subject_GND | (DE-588)4039983-7 (DE-588)4057381-3 (DE-588)4038971-6 (DE-588)4143413-4 |
| title | Steroid Receptor Methods Protocols and Assays |
| title_auth | Steroid Receptor Methods Protocols and Assays |
| title_exact_search | Steroid Receptor Methods Protocols and Assays |
| title_full | Steroid Receptor Methods Protocols and Assays edited by Benjamin A. Lieberman |
| title_fullStr | Steroid Receptor Methods Protocols and Assays edited by Benjamin A. Lieberman |
| title_full_unstemmed | Steroid Receptor Methods Protocols and Assays edited by Benjamin A. Lieberman |
| title_short | Steroid Receptor Methods |
| title_sort | steroid receptor methods protocols and assays |
| title_sub | Protocols and Assays |
| topic | Life Sciences Biochemistry, general Life sciences Biochemistry Molekularbiologie (DE-588)4039983-7 gnd Steroidhormonrezeptor (DE-588)4057381-3 gnd Methode (DE-588)4038971-6 gnd |
| topic_facet | Life Sciences Biochemistry, general Life sciences Biochemistry Molekularbiologie Steroidhormonrezeptor Methode Aufsatzsammlung |
| url | https://doi.org/10.1385/1592591159 |
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