Fungal Secondary Metabolism: Methods and Protocols
Filamentous fungi have long been known for their ability to produce an enormous range of unusual chemical compounds known as secondary metabolites, many of which have potentially useful antibiotic or pharmacological properties. Recent focus on fungal genomics coupled with advances in detection and m...
Saved in:
| Other Authors: | , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2012
|
| Series: | Methods in Molecular Biology, Methods and Protocols
944 |
| Subjects: | |
| Online Access: | UBR01 TUM01 Volltext |
| Summary: | Filamentous fungi have long been known for their ability to produce an enormous range of unusual chemical compounds known as secondary metabolites, many of which have potentially useful antibiotic or pharmacological properties. Recent focus on fungal genomics coupled with advances in detection and molecular manipulation techniques has galvanized a revitalization of this field. Fungal Secondary Metabolism: Methods and Protocols is aimed at providing the key methodologies currently in use and necessary for accessing and exploiting the natural product information provided by the genomes of this large and varied kingdom. Written by active researchers in the field, the chapters deal with all the steps necessary, from optimization of fungal culture conditions for metabolite production, through rapid genome sequencing and bioinformatics, and genetic manipulations for functional analysis, to detection and testing of metabolites. In addition, chapters on basic science address approaches to the genetic regulation, protein biochemistry, and cellular localization of the biosynthetic pathways. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and hands-on, Fungal Secondary Metabolism: Methods and Protocols encourages new investigators to enter the field and expands upon the expertise and range of skills of those already researching fungal natural products |
| Physical Description: | 1 Online-Ressource (XII, 288 p. 60 illus., 32 illus. in color) |
| ISBN: | 9781627031226 |
| DOI: | 10.1007/978-1-62703-122-6 |
Staff View
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Record in the Search Index
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| dewey-full | 579 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 579 - Microorganisms, fungi & algae |
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| discipline | Biologie |
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| spelling | Fungal Secondary Metabolism Methods and Protocols edited by Nancy P. Keller, Geoffrey Turner Totowa, NJ Humana Press 2012 1 Online-Ressource (XII, 288 p. 60 illus., 32 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 944 Filamentous fungi have long been known for their ability to produce an enormous range of unusual chemical compounds known as secondary metabolites, many of which have potentially useful antibiotic or pharmacological properties. Recent focus on fungal genomics coupled with advances in detection and molecular manipulation techniques has galvanized a revitalization of this field. Fungal Secondary Metabolism: Methods and Protocols is aimed at providing the key methodologies currently in use and necessary for accessing and exploiting the natural product information provided by the genomes of this large and varied kingdom. Written by active researchers in the field, the chapters deal with all the steps necessary, from optimization of fungal culture conditions for metabolite production, through rapid genome sequencing and bioinformatics, and genetic manipulations for functional analysis, to detection and testing of metabolites. In addition, chapters on basic science address approaches to the genetic regulation, protein biochemistry, and cellular localization of the biosynthetic pathways. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and hands-on, Fungal Secondary Metabolism: Methods and Protocols encourages new investigators to enter the field and expands upon the expertise and range of skills of those already researching fungal natural products Life Sciences Microbiology Eukaryotic Microbiology Gene Expression Life sciences Gene expression Biotechnologie (DE-588)4069491-4 gnd rswk-swf Fadenpilze (DE-588)4170451-4 gnd rswk-swf Sekundärmetabolit (DE-588)4300564-0 gnd rswk-swf Fadenpilze (DE-588)4170451-4 s Sekundärmetabolit (DE-588)4300564-0 s Biotechnologie (DE-588)4069491-4 s 1\p DE-604 Keller, Nancy P. edt Turner, Geoffrey edt Erscheint auch als Druck-Ausgabe 9781627031219 https://doi.org/10.1007/978-1-62703-122-6 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Fungal Secondary Metabolism Methods and Protocols Life Sciences Microbiology Eukaryotic Microbiology Gene Expression Life sciences Gene expression Biotechnologie (DE-588)4069491-4 gnd Fadenpilze (DE-588)4170451-4 gnd Sekundärmetabolit (DE-588)4300564-0 gnd |
| subject_GND | (DE-588)4069491-4 (DE-588)4170451-4 (DE-588)4300564-0 |
| title | Fungal Secondary Metabolism Methods and Protocols |
| title_auth | Fungal Secondary Metabolism Methods and Protocols |
| title_exact_search | Fungal Secondary Metabolism Methods and Protocols |
| title_full | Fungal Secondary Metabolism Methods and Protocols edited by Nancy P. Keller, Geoffrey Turner |
| title_fullStr | Fungal Secondary Metabolism Methods and Protocols edited by Nancy P. Keller, Geoffrey Turner |
| title_full_unstemmed | Fungal Secondary Metabolism Methods and Protocols edited by Nancy P. Keller, Geoffrey Turner |
| title_short | Fungal Secondary Metabolism |
| title_sort | fungal secondary metabolism methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Microbiology Eukaryotic Microbiology Gene Expression Life sciences Gene expression Biotechnologie (DE-588)4069491-4 gnd Fadenpilze (DE-588)4170451-4 gnd Sekundärmetabolit (DE-588)4300564-0 gnd |
| topic_facet | Life Sciences Microbiology Eukaryotic Microbiology Gene Expression Life sciences Gene expression Biotechnologie Fadenpilze Sekundärmetabolit |
| url | https://doi.org/10.1007/978-1-62703-122-6 |
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