Phosphatase Modulators:
Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one "how to" manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapte...
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| Other Authors: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2013
|
| Series: | Methods in Molecular Biology, Methods and Protocols
1053 |
| Subjects: | |
| Online Access: | UBR01 TUM01 Volltext |
| Summary: | Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one "how to" manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making "go/no-go" decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results. Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts |
| Physical Description: | 1 Online-Ressource (X, 315 p. 75 illus., 45 illus. in color) |
| ISBN: | 9781627035620 |
| DOI: | 10.1007/978-1-62703-562-0 |
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| isbn | 9781627035620 |
| language | English |
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| spelling | Phosphatase Modulators edited by José Luis Millán Totowa, NJ Humana Press 2013 1 Online-Ressource (X, 315 p. 75 illus., 45 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 1053 Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one "how to" manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making "go/no-go" decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results. Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts Biomedicine Pharmacology/Toxicology Medicinal Chemistry Pharmacy Medicine Pharmacology Medicinal chemistry Millán, José Luis edt Erscheint auch als Druck-Ausgabe 9781627035613 https://doi.org/10.1007/978-1-62703-562-0 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Phosphatase Modulators Biomedicine Pharmacology/Toxicology Medicinal Chemistry Pharmacy Medicine Pharmacology Medicinal chemistry |
| title | Phosphatase Modulators |
| title_auth | Phosphatase Modulators |
| title_exact_search | Phosphatase Modulators |
| title_full | Phosphatase Modulators edited by José Luis Millán |
| title_fullStr | Phosphatase Modulators edited by José Luis Millán |
| title_full_unstemmed | Phosphatase Modulators edited by José Luis Millán |
| title_short | Phosphatase Modulators |
| title_sort | phosphatase modulators |
| topic | Biomedicine Pharmacology/Toxicology Medicinal Chemistry Pharmacy Medicine Pharmacology Medicinal chemistry |
| topic_facet | Biomedicine Pharmacology/Toxicology Medicinal Chemistry Pharmacy Medicine Pharmacology Medicinal chemistry |
| url | https://doi.org/10.1007/978-1-62703-562-0 |
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