p53 Protocols:
Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal its unique structural features and biochemical functions. In p53 Protocols, Sumitra and Swati Palit Deb have assembled an indispensable collection of novel techniques that have proven most useful for studying t...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Springer New York
2003
|
| Schriftenreihe: | Methods in Molecular Biology
234 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal its unique structural features and biochemical functions. In p53 Protocols, Sumitra and Swati Palit Deb have assembled an indispensable collection of novel techniques that have proven most useful for studying the physiological properties of p53 both in vitro and in vivo. Described by leading basic and clinical researchers who have successfully used the methods, the techniques provide proven solutions to problems in studying the purification, target identification, gene expression, quantitation, interaction, signaling, transactivation, and transrepression of p53. The methods are also useful for delineating the functions of other proteins that may act as tumor or growth suppressors. Each technique includes step-by-step instructions, troubleshooting notes, a theoretical review, and discussion of associated problems that might arise during the course of investigation. Special effort has been made to discuss problems and their solutions to help ease the learning curve when standardizing a new method. Diverse and highly practical, p53 Protocols offers both beginning and experienced researchers in cancer biology a gold-standard compendium of readily reproducible techniques for studying p53 and related proteins |
| Beschreibung: | 1 Online-Ressource (XI, 280 p) |
| ISBN: | 9781592594085 |
| DOI: | 10.1385/1592594085 |
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| 520 | |a Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal its unique structural features and biochemical functions. In p53 Protocols, Sumitra and Swati Palit Deb have assembled an indispensable collection of novel techniques that have proven most useful for studying the physiological properties of p53 both in vitro and in vivo. Described by leading basic and clinical researchers who have successfully used the methods, the techniques provide proven solutions to problems in studying the purification, target identification, gene expression, quantitation, interaction, signaling, transactivation, and transrepression of p53. The methods are also useful for delineating the functions of other proteins that may act as tumor or growth suppressors. Each technique includes step-by-step instructions, troubleshooting notes, a theoretical review, and discussion of associated problems that might arise during the course of investigation. Special effort has been made to discuss problems and their solutions to help ease the learning curve when standardizing a new method. Diverse and highly practical, p53 Protocols offers both beginning and experienced researchers in cancer biology a gold-standard compendium of readily reproducible techniques for studying p53 and related proteins | ||
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| discipline | Biologie Medizin |
| doi_str_mv | 10.1385/1592594085 |
| format | Electronic eBook |
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| spelling | p53 Protocols edited by Sumitra Deb, Swati Palit Deb Totowa, NJ Springer New York 2003 1 Online-Ressource (XI, 280 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 234 Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal its unique structural features and biochemical functions. In p53 Protocols, Sumitra and Swati Palit Deb have assembled an indispensable collection of novel techniques that have proven most useful for studying the physiological properties of p53 both in vitro and in vivo. Described by leading basic and clinical researchers who have successfully used the methods, the techniques provide proven solutions to problems in studying the purification, target identification, gene expression, quantitation, interaction, signaling, transactivation, and transrepression of p53. The methods are also useful for delineating the functions of other proteins that may act as tumor or growth suppressors. Each technique includes step-by-step instructions, troubleshooting notes, a theoretical review, and discussion of associated problems that might arise during the course of investigation. Special effort has been made to discuss problems and their solutions to help ease the learning curve when standardizing a new method. Diverse and highly practical, p53 Protocols offers both beginning and experienced researchers in cancer biology a gold-standard compendium of readily reproducible techniques for studying p53 and related proteins Life Sciences Cell Biology Life sciences Cell biology Protein p53 (DE-588)4176550-3 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Protein p53 (DE-588)4176550-3 s DE-604 Deb, Sumitra edt Deb, Swati Palit edt Erscheint auch als Druck-Ausgabe 9781588291066 https://doi.org/10.1385/1592594085 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | p53 Protocols Life Sciences Cell Biology Life sciences Cell biology Protein p53 (DE-588)4176550-3 gnd |
| subject_GND | (DE-588)4176550-3 (DE-588)4143413-4 |
| title | p53 Protocols |
| title_auth | p53 Protocols |
| title_exact_search | p53 Protocols |
| title_full | p53 Protocols edited by Sumitra Deb, Swati Palit Deb |
| title_fullStr | p53 Protocols edited by Sumitra Deb, Swati Palit Deb |
| title_full_unstemmed | p53 Protocols edited by Sumitra Deb, Swati Palit Deb |
| title_short | p53 Protocols |
| title_sort | p53 protocols |
| topic | Life Sciences Cell Biology Life sciences Cell biology Protein p53 (DE-588)4176550-3 gnd |
| topic_facet | Life Sciences Cell Biology Life sciences Cell biology Protein p53 Aufsatzsammlung |
| url | https://doi.org/10.1385/1592594085 |
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