Hypertension: Methods and Protocols
Our understanding of the pathogenesis of hypertension and the development of new therapies for its management have each proven to be directly dependent on the availability and application of novel molecular biological methodologies. In Hypertension: Methods and Protocols, a panel of recognized exper...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2005
|
| Schriftenreihe: | Methods In Molecular Medicine™
108 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | Our understanding of the pathogenesis of hypertension and the development of new therapies for its management have each proven to be directly dependent on the availability and application of novel molecular biological methodologies. In Hypertension: Methods and Protocols, a panel of recognized experts from key institutions around the world describes in step-by-step detail many new and essential molecular techniques for cardiovascular hypertension research. The methods presented range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using adenoviral and nonviral (polymers, liposomes, and antisense agents) vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. A review of bioinformatic resources for pharmacogenomics describes the application of in silico strategies to identify nuclear matrix attachment regions. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Hypertension: Methods and Protocols offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success |
| Beschreibung: | 1 Online-Ressource (XVI, 502 p. 98 illus) |
| ISBN: | 9781592598502 |
| DOI: | 10.1385/1592598501 |
Internformat
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| spelling | Hypertension Methods and Protocols edited by Jérôme P. Fennell, Andrew H. Baker Totowa, NJ Humana Press 2005 1 Online-Ressource (XVI, 502 p. 98 illus) txt rdacontent c rdamedia cr rdacarrier Methods In Molecular Medicine™ 108 Our understanding of the pathogenesis of hypertension and the development of new therapies for its management have each proven to be directly dependent on the availability and application of novel molecular biological methodologies. In Hypertension: Methods and Protocols, a panel of recognized experts from key institutions around the world describes in step-by-step detail many new and essential molecular techniques for cardiovascular hypertension research. The methods presented range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using adenoviral and nonviral (polymers, liposomes, and antisense agents) vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. A review of bioinformatic resources for pharmacogenomics describes the application of in silico strategies to identify nuclear matrix attachment regions. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Hypertension: Methods and Protocols offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success Medicine & Public Health Cardiology Medicine Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Hypertonie (DE-588)4026372-1 gnd rswk-swf Hypertonie (DE-588)4026372-1 s Molekulare Medizin (DE-588)4543844-4 s b DE-604 Fennell, Jérôme P. edt Baker, Andrew H. edt Erscheint auch als Druck-Ausgabe 9781588293237 https://doi.org/10.1385/1592598501 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Hypertension Methods and Protocols Medicine & Public Health Cardiology Medicine Molekulare Medizin (DE-588)4543844-4 gnd Hypertonie (DE-588)4026372-1 gnd |
| subject_GND | (DE-588)4543844-4 (DE-588)4026372-1 |
| title | Hypertension Methods and Protocols |
| title_auth | Hypertension Methods and Protocols |
| title_exact_search | Hypertension Methods and Protocols |
| title_full | Hypertension Methods and Protocols edited by Jérôme P. Fennell, Andrew H. Baker |
| title_fullStr | Hypertension Methods and Protocols edited by Jérôme P. Fennell, Andrew H. Baker |
| title_full_unstemmed | Hypertension Methods and Protocols edited by Jérôme P. Fennell, Andrew H. Baker |
| title_short | Hypertension |
| title_sort | hypertension methods and protocols |
| title_sub | Methods and Protocols |
| topic | Medicine & Public Health Cardiology Medicine Molekulare Medizin (DE-588)4543844-4 gnd Hypertonie (DE-588)4026372-1 gnd |
| topic_facet | Medicine & Public Health Cardiology Medicine Molekulare Medizin Hypertonie |
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