Psychiatric Genetics: Methods and Reviews
Enthusiasm about the role that genetics plays in our understanding of behavioral phenotypes has led to the development of many new epidemiological and statistical strategies, as well as to refinements in phenotype analysis. In Psychiatric Genetics: Methods and Reviews, hands-on experts comprehensive...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2003
|
| Schriftenreihe: | Methods in Molecular Medicine™
77 |
| Schlagworte: | |
| Online-Zugang: | DE-355 DE-91 Volltext |
| Zusammenfassung: | Enthusiasm about the role that genetics plays in our understanding of behavioral phenotypes has led to the development of many new epidemiological and statistical strategies, as well as to refinements in phenotype analysis. In Psychiatric Genetics: Methods and Reviews, hands-on experts comprehensively review the tools and methods currently available to uncover the genetic basis of psychiatric disorders, and then demonstrate through archetypical examples how these strategies can be used. Casting their net widely, the authors critically examine the key methodological issues involved in phenotypic analysis-including study design, molecular techniques, clinical interviews, and population sampling methods-and discuss new and alternate strategies that identify candidate symptoms and endophenotypes with better genetic validity. These strategies suggest cognitive intermediate phenotypes in schizophrenia, show how personality disorders may generate biologically mediated traits in the full-blown disorders, and yield data about P50 and P300 as endophenotypes in schizophrenia and alcoholism. One of the most promising approaches for the identification of valid phenotypes-the union of neuropsychological experimental designs and in vivo physiological brain mapping-is also discussed. Practical and timely, Psychiatric Genetics: Methods and Reviews lays the cornerstone for the new diagnostics in psychiatric genetics-the unraveling of the genetic basis of psychiatric disorders and the development of new therapies through the precise identification of the phenotypes involved |
| Beschreibung: | 1 Online-Ressource (IX, 268 p. 7 illus) |
| ISBN: | 9781592593484 |
| DOI: | 10.1385/1592593488 |
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| spelling | Psychiatric Genetics Methods and Reviews edited by Marion Leboyer, Frank Bellivier Totowa, NJ Humana Press 2003 1 Online-Ressource (IX, 268 p. 7 illus) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine™ 77 Enthusiasm about the role that genetics plays in our understanding of behavioral phenotypes has led to the development of many new epidemiological and statistical strategies, as well as to refinements in phenotype analysis. In Psychiatric Genetics: Methods and Reviews, hands-on experts comprehensively review the tools and methods currently available to uncover the genetic basis of psychiatric disorders, and then demonstrate through archetypical examples how these strategies can be used. Casting their net widely, the authors critically examine the key methodological issues involved in phenotypic analysis-including study design, molecular techniques, clinical interviews, and population sampling methods-and discuss new and alternate strategies that identify candidate symptoms and endophenotypes with better genetic validity. These strategies suggest cognitive intermediate phenotypes in schizophrenia, show how personality disorders may generate biologically mediated traits in the full-blown disorders, and yield data about P50 and P300 as endophenotypes in schizophrenia and alcoholism. One of the most promising approaches for the identification of valid phenotypes-the union of neuropsychological experimental designs and in vivo physiological brain mapping-is also discussed. Practical and timely, Psychiatric Genetics: Methods and Reviews lays the cornerstone for the new diagnostics in psychiatric genetics-the unraveling of the genetic basis of psychiatric disorders and the development of new therapies through the precise identification of the phenotypes involved Medicine & Public Health Psychiatry Medicine Molekulare Diagnostik (DE-588)4589005-5 gnd rswk-swf Genetik (DE-588)4071711-2 gnd rswk-swf Psychische Störung (DE-588)4047686-8 gnd rswk-swf Psychische Störung (DE-588)4047686-8 s Genetik (DE-588)4071711-2 s Molekulare Diagnostik (DE-588)4589005-5 s b DE-604 Leboyer, Marion edt Bellivier, Frank edt Erscheint auch als Druck-Ausgabe 9781588290373 https://doi.org/10.1385/1592593488 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Psychiatric Genetics Methods and Reviews Medicine & Public Health Psychiatry Medicine Molekulare Diagnostik (DE-588)4589005-5 gnd Genetik (DE-588)4071711-2 gnd Psychische Störung (DE-588)4047686-8 gnd |
| subject_GND | (DE-588)4589005-5 (DE-588)4071711-2 (DE-588)4047686-8 |
| title | Psychiatric Genetics Methods and Reviews |
| title_auth | Psychiatric Genetics Methods and Reviews |
| title_exact_search | Psychiatric Genetics Methods and Reviews |
| title_full | Psychiatric Genetics Methods and Reviews edited by Marion Leboyer, Frank Bellivier |
| title_fullStr | Psychiatric Genetics Methods and Reviews edited by Marion Leboyer, Frank Bellivier |
| title_full_unstemmed | Psychiatric Genetics Methods and Reviews edited by Marion Leboyer, Frank Bellivier |
| title_short | Psychiatric Genetics |
| title_sort | psychiatric genetics methods and reviews |
| title_sub | Methods and Reviews |
| topic | Medicine & Public Health Psychiatry Medicine Molekulare Diagnostik (DE-588)4589005-5 gnd Genetik (DE-588)4071711-2 gnd Psychische Störung (DE-588)4047686-8 gnd |
| topic_facet | Medicine & Public Health Psychiatry Medicine Molekulare Diagnostik Genetik Psychische Störung |
| url | https://doi.org/10.1385/1592593488 |
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