Drug Target miRNA: Methods and Protocols
This volume provides a concise and technical discussion of recently developed approaches to overcome challenges, such as pharmacodynamics and pharmacokinetics difficulties, in miRNA drug discovery. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or...
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| Other Authors: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
2017
|
| Series: | Methods in Molecular Biology
1517 |
| Subjects: | |
| Online Access: | UBR01 TUM01 Volltext |
| Summary: | This volume provides a concise and technical discussion of recently developed approaches to overcome challenges, such as pharmacodynamics and pharmacokinetics difficulties, in miRNA drug discovery. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents’ limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Drug Target miRNA: Methods and Protocols is a valuable resource for anyone interested in the ever-evolving field of miRNA drug discovery. |
| Physical Description: | 1 Online-Ressource (XI, 319 p. 94 illus., 62 illus. in color) |
| ISBN: | 9781493965632 |
| DOI: | 10.1007/978-1-4939-6563-2 |
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| spelling | Drug Target miRNA Methods and Protocols edited by Marco F. Schmidt New York, NY Springer New York 2017 1 Online-Ressource (XI, 319 p. 94 illus., 62 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1517 This volume provides a concise and technical discussion of recently developed approaches to overcome challenges, such as pharmacodynamics and pharmacokinetics difficulties, in miRNA drug discovery. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents’ limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Drug Target miRNA: Methods and Protocols is a valuable resource for anyone interested in the ever-evolving field of miRNA drug discovery. Biomedicine Pharmacology/Toxicology Medicine Pharmacology Schmidt, Marco F. edt Erscheint auch als Druck-Ausgabe 9781493965618 https://doi.org/10.1007/978-1-4939-6563-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Drug Target miRNA Methods and Protocols Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
| title | Drug Target miRNA Methods and Protocols |
| title_auth | Drug Target miRNA Methods and Protocols |
| title_exact_search | Drug Target miRNA Methods and Protocols |
| title_full | Drug Target miRNA Methods and Protocols edited by Marco F. Schmidt |
| title_fullStr | Drug Target miRNA Methods and Protocols edited by Marco F. Schmidt |
| title_full_unstemmed | Drug Target miRNA Methods and Protocols edited by Marco F. Schmidt |
| title_short | Drug Target miRNA |
| title_sort | drug target mirna methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
| topic_facet | Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
| url | https://doi.org/10.1007/978-1-4939-6563-2 |
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