The Blood-Brain and Other Neural Barriers: Reviews and Protocols
Evolving technologies starting with tracer studies, and more recently with genomics and proteomics, have provided novel information about the molecular properties of cerebral endothelium and astrocytes; however, further studies must be done in animal models of neurological diseases and in humans to...
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| Other Authors: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2011
|
| Series: | Methods in Molecular Biology, Methods and Protocols
686 |
| Subjects: | |
| Online Access: | UBR01 TUM01 Volltext |
| Summary: | Evolving technologies starting with tracer studies, and more recently with genomics and proteomics, have provided novel information about the molecular properties of cerebral endothelium and astrocytes; however, further studies must be done in animal models of neurological diseases and in humans to get a clearer understanding of the pathogenesis of blood-brain barrier (BBB) breakdown in nervous system diseases. In The Blood-Brain and Other Neural Barriers: Reviews and Protocols, experts in the field present a series of cutting-edge protocols which can be used to study the barriers. Opening with detailed information on components of the neurovascular unit as well as the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, the book continues with meticulous techniques to image the barriers in humans and experimental animals, followed by cutting-edge molecular techniques to study the BBB and novel models to study the barriers, and it concludes with techniques for the delivery of therapeutic agents across the BBB. Written in the highly successful Methods in Molecular Biology™ series format, protocol chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, The Blood-Brain and Other Neural Barriers: Reviews and Protocols will aid the research efforts of not only graduate students but also more experienced investigators and support future studies of these vital systems |
| Physical Description: | 1 Online-Ressource (XIV, 502 p. 102 illus., 21 illus. in color) |
| ISBN: | 9781607619383 |
| DOI: | 10.1007/978-1-60761-938-3 |
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| 520 | |a Evolving technologies starting with tracer studies, and more recently with genomics and proteomics, have provided novel information about the molecular properties of cerebral endothelium and astrocytes; however, further studies must be done in animal models of neurological diseases and in humans to get a clearer understanding of the pathogenesis of blood-brain barrier (BBB) breakdown in nervous system diseases. In The Blood-Brain and Other Neural Barriers: Reviews and Protocols, experts in the field present a series of cutting-edge protocols which can be used to study the barriers. Opening with detailed information on components of the neurovascular unit as well as the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, the book continues with meticulous techniques to image the barriers in humans and experimental animals, followed by cutting-edge molecular techniques to study the BBB and novel models to study the barriers, and it concludes with techniques for the delivery of therapeutic agents across the BBB. Written in the highly successful Methods in Molecular Biology™ series format, protocol chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, The Blood-Brain and Other Neural Barriers: Reviews and Protocols will aid the research efforts of not only graduate students but also more experienced investigators and support future studies of these vital systems | ||
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| spelling | The Blood-Brain and Other Neural Barriers Reviews and Protocols edited by Sukriti Nag Totowa, NJ Humana Press 2011 1 Online-Ressource (XIV, 502 p. 102 illus., 21 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 686 Evolving technologies starting with tracer studies, and more recently with genomics and proteomics, have provided novel information about the molecular properties of cerebral endothelium and astrocytes; however, further studies must be done in animal models of neurological diseases and in humans to get a clearer understanding of the pathogenesis of blood-brain barrier (BBB) breakdown in nervous system diseases. In The Blood-Brain and Other Neural Barriers: Reviews and Protocols, experts in the field present a series of cutting-edge protocols which can be used to study the barriers. Opening with detailed information on components of the neurovascular unit as well as the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, the book continues with meticulous techniques to image the barriers in humans and experimental animals, followed by cutting-edge molecular techniques to study the BBB and novel models to study the barriers, and it concludes with techniques for the delivery of therapeutic agents across the BBB. Written in the highly successful Methods in Molecular Biology™ series format, protocol chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, The Blood-Brain and Other Neural Barriers: Reviews and Protocols will aid the research efforts of not only graduate students but also more experienced investigators and support future studies of these vital systems Biomedicine Neurosciences Human Physiology Neurochemistry Medicine Human physiology Nag, Sukriti edt Erscheint auch als Druck-Ausgabe 9781607619376 https://doi.org/10.1007/978-1-60761-938-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | The Blood-Brain and Other Neural Barriers Reviews and Protocols Biomedicine Neurosciences Human Physiology Neurochemistry Medicine Human physiology |
| title | The Blood-Brain and Other Neural Barriers Reviews and Protocols |
| title_auth | The Blood-Brain and Other Neural Barriers Reviews and Protocols |
| title_exact_search | The Blood-Brain and Other Neural Barriers Reviews and Protocols |
| title_full | The Blood-Brain and Other Neural Barriers Reviews and Protocols edited by Sukriti Nag |
| title_fullStr | The Blood-Brain and Other Neural Barriers Reviews and Protocols edited by Sukriti Nag |
| title_full_unstemmed | The Blood-Brain and Other Neural Barriers Reviews and Protocols edited by Sukriti Nag |
| title_short | The Blood-Brain and Other Neural Barriers |
| title_sort | the blood brain and other neural barriers reviews and protocols |
| title_sub | Reviews and Protocols |
| topic | Biomedicine Neurosciences Human Physiology Neurochemistry Medicine Human physiology |
| topic_facet | Biomedicine Neurosciences Human Physiology Neurochemistry Medicine Human physiology |
| url | https://doi.org/10.1007/978-1-60761-938-3 |
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