Haemophilus influenzae Protocols:
As the second leading bacterial cause of community-acquired pneumonia, H. influenzae accounts for many thousands of deaths per year worldwide, and is a prime candidate for the identification of targets that can lead to the development of novel vaccines and antibiotics. In Haemophilus influenzae Prot...
Gespeichert in:
Weitere Verfasser: | , , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
2003
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Schriftenreihe: | Methods in Molecular Medicine™
71 |
Schlagworte: | |
Online-Zugang: | UBR01 TUM01 Volltext |
Zusammenfassung: | As the second leading bacterial cause of community-acquired pneumonia, H. influenzae accounts for many thousands of deaths per year worldwide, and is a prime candidate for the identification of targets that can lead to the development of novel vaccines and antibiotics. In Haemophilus influenzae Protocols, leading research scientists and infectious disease specialists detail in a readily reproducible format the major molecular and immunological techniques for exploring the pathogenicity of this significant bacterium. Described with step-by-step instructions to ensure robust and successful experimental results, the techniques cover plasmid analysis, proteomics, genomics, DNA array technology, gene expression, mutagenesis (transposon and nontransposon), and structural analysis. The antibody techniques presented include IVIAT, ELISA, and opsonophagocytosis assays. Also included are reviews of the pathogenesis of NTHi and Hib, methods for working with the organism, culture and storage conditions, molecular diagnosis, and systems for exploring pathogenesis in both in vitro and animal models. Comprehensive and highly practical, Haemophilus influenzae Protocols offers a unique collection of powerful molecular methods that illuminate not only how the bacterium causes disease, but also how best to develop much-needed new vaccines and antibiotics against it |
Beschreibung: | 1 Online-Ressource (XI, 333 p) |
ISBN: | 9781592593217 |
DOI: | 10.1385/1592593216 |
Internformat
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520 | |a As the second leading bacterial cause of community-acquired pneumonia, H. influenzae accounts for many thousands of deaths per year worldwide, and is a prime candidate for the identification of targets that can lead to the development of novel vaccines and antibiotics. In Haemophilus influenzae Protocols, leading research scientists and infectious disease specialists detail in a readily reproducible format the major molecular and immunological techniques for exploring the pathogenicity of this significant bacterium. Described with step-by-step instructions to ensure robust and successful experimental results, the techniques cover plasmid analysis, proteomics, genomics, DNA array technology, gene expression, mutagenesis (transposon and nontransposon), and structural analysis. The antibody techniques presented include IVIAT, ELISA, and opsonophagocytosis assays. Also included are reviews of the pathogenesis of NTHi and Hib, methods for working with the organism, culture and storage conditions, molecular diagnosis, and systems for exploring pathogenesis in both in vitro and animal models. Comprehensive and highly practical, Haemophilus influenzae Protocols offers a unique collection of powerful molecular methods that illuminate not only how the bacterium causes disease, but also how best to develop much-needed new vaccines and antibiotics against it | ||
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Datensatz im Suchindex
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any_adam_object | |
author2 | Herbert, Mark A. Hood, Derek W. Moxon, E. Richard |
author2_role | edt edt edt |
author2_variant | m a h ma mah d w h dw dwh e r m er erm |
author_facet | Herbert, Mark A. Hood, Derek W. Moxon, E. Richard |
building | Verbundindex |
bvnumber | BV044950619 |
collection | ZDB-2-PRO |
ctrlnum | (ZDB-2-PRO)978-1-59259-321-7 (OCoLC)890644703 (DE-599)BVBBV044950619 |
dewey-full | 616.9 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 616 - Diseases |
dewey-raw | 616.9 |
dewey-search | 616.9 |
dewey-sort | 3616.9 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1385/1592593216 |
format | Electronic eBook |
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illustrated | Not Illustrated |
indexdate | 2024-07-10T08:05:34Z |
institution | BVB |
isbn | 9781592593217 |
language | English |
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publisher | Humana Press |
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spelling | Haemophilus influenzae Protocols edited by Mark A. Herbert, Derek W. Hood, E. Richard Moxon Totowa, NJ Humana Press 2003 1 Online-Ressource (XI, 333 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine™ 71 As the second leading bacterial cause of community-acquired pneumonia, H. influenzae accounts for many thousands of deaths per year worldwide, and is a prime candidate for the identification of targets that can lead to the development of novel vaccines and antibiotics. In Haemophilus influenzae Protocols, leading research scientists and infectious disease specialists detail in a readily reproducible format the major molecular and immunological techniques for exploring the pathogenicity of this significant bacterium. Described with step-by-step instructions to ensure robust and successful experimental results, the techniques cover plasmid analysis, proteomics, genomics, DNA array technology, gene expression, mutagenesis (transposon and nontransposon), and structural analysis. The antibody techniques presented include IVIAT, ELISA, and opsonophagocytosis assays. Also included are reviews of the pathogenesis of NTHi and Hib, methods for working with the organism, culture and storage conditions, molecular diagnosis, and systems for exploring pathogenesis in both in vitro and animal models. Comprehensive and highly practical, Haemophilus influenzae Protocols offers a unique collection of powerful molecular methods that illuminate not only how the bacterium causes disease, but also how best to develop much-needed new vaccines and antibiotics against it Medicine & Public Health Infectious Diseases Medicine Infectious diseases Herbert, Mark A. edt Hood, Derek W. edt Moxon, E. Richard edt Erscheint auch als Druck-Ausgabe 9780896039285 https://doi.org/10.1385/1592593216 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Haemophilus influenzae Protocols Medicine & Public Health Infectious Diseases Medicine Infectious diseases |
title | Haemophilus influenzae Protocols |
title_auth | Haemophilus influenzae Protocols |
title_exact_search | Haemophilus influenzae Protocols |
title_full | Haemophilus influenzae Protocols edited by Mark A. Herbert, Derek W. Hood, E. Richard Moxon |
title_fullStr | Haemophilus influenzae Protocols edited by Mark A. Herbert, Derek W. Hood, E. Richard Moxon |
title_full_unstemmed | Haemophilus influenzae Protocols edited by Mark A. Herbert, Derek W. Hood, E. Richard Moxon |
title_short | Haemophilus influenzae Protocols |
title_sort | haemophilus influenzae protocols |
topic | Medicine & Public Health Infectious Diseases Medicine Infectious diseases |
topic_facet | Medicine & Public Health Infectious Diseases Medicine Infectious diseases |
url | https://doi.org/10.1385/1592593216 |
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