Superantigen Protocols:
Superantigens, a class of proteins produced by bacteria and microbes, cause diseases ranging from food poisoning to toxic shock, but can also be used to understand these pathologies and devise therapeutic agents to combat them. In Superantigen Protocols, leading researchers in the biological, chemic...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2003
|
| Schriftenreihe: | Methods in Molecular Biology™
214 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Superantigens, a class of proteins produced by bacteria and microbes, cause diseases ranging from food poisoning to toxic shock, but can also be used to understand these pathologies and devise therapeutic agents to combat them. In Superantigen Protocols, leading researchers in the biological, chemical, and physical investigation of superantigens describe in step-by-step detail their best experimental techniques to assess the physical characteristics and biological effects of these potent activators of the immune system. The protocols range from those for investigating the interactions of superantigens with cellular receptors to those for the analysis of their immunological and biological effects, including methods for using BIOcore to determine binding kinetics and establishing various lymphocyte cell culture systems. There are also accounts of such methods as the RNase protection assay, cytokine ELISA, FACS analysis, and cytokine production at the single cell level. Additional techniques for the discovery of new activators of the immune system, the development of new therapeutics for the suppression of superantigen-induced effects, and the treatment of inflammatory diseases are detailed. Comprehensive and cutting-edge, Superantigen Protocols provides a broad range of novel immunological and biochemical techniques that can be successfully applied not only to the structural, functional, and clinical properties of superantigens, but also to the many varieties of such proteins and to new cellular systems |
| Beschreibung: | 1 Online-Ressource (XII, 259 p. 59 illus., 6 illus. in color) |
| ISBN: | 9781592593675 |
| DOI: | 10.1385/1592593674 |
Internformat
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| 520 | |a Superantigens, a class of proteins produced by bacteria and microbes, cause diseases ranging from food poisoning to toxic shock, but can also be used to understand these pathologies and devise therapeutic agents to combat them. In Superantigen Protocols, leading researchers in the biological, chemical, and physical investigation of superantigens describe in step-by-step detail their best experimental techniques to assess the physical characteristics and biological effects of these potent activators of the immune system. The protocols range from those for investigating the interactions of superantigens with cellular receptors to those for the analysis of their immunological and biological effects, including methods for using BIOcore to determine binding kinetics and establishing various lymphocyte cell culture systems. There are also accounts of such methods as the RNase protection assay, cytokine ELISA, FACS analysis, and cytokine production at the single cell level. Additional techniques for the discovery of new activators of the immune system, the development of new therapeutics for the suppression of superantigen-induced effects, and the treatment of inflammatory diseases are detailed. Comprehensive and cutting-edge, Superantigen Protocols provides a broad range of novel immunological and biochemical techniques that can be successfully applied not only to the structural, functional, and clinical properties of superantigens, but also to the many varieties of such proteins and to new cellular systems | ||
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| spelling | Superantigen Protocols edited by Teresa Krakauer Totowa, NJ Humana Press 2003 1 Online-Ressource (XII, 259 p. 59 illus., 6 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 214 Superantigens, a class of proteins produced by bacteria and microbes, cause diseases ranging from food poisoning to toxic shock, but can also be used to understand these pathologies and devise therapeutic agents to combat them. In Superantigen Protocols, leading researchers in the biological, chemical, and physical investigation of superantigens describe in step-by-step detail their best experimental techniques to assess the physical characteristics and biological effects of these potent activators of the immune system. The protocols range from those for investigating the interactions of superantigens with cellular receptors to those for the analysis of their immunological and biological effects, including methods for using BIOcore to determine binding kinetics and establishing various lymphocyte cell culture systems. There are also accounts of such methods as the RNase protection assay, cytokine ELISA, FACS analysis, and cytokine production at the single cell level. Additional techniques for the discovery of new activators of the immune system, the development of new therapeutics for the suppression of superantigen-induced effects, and the treatment of inflammatory diseases are detailed. Comprehensive and cutting-edge, Superantigen Protocols provides a broad range of novel immunological and biochemical techniques that can be successfully applied not only to the structural, functional, and clinical properties of superantigens, but also to the many varieties of such proteins and to new cellular systems Biomedicine Immunology Medicine Superantigen (DE-588)4312998-5 gnd rswk-swf Untersuchungsmethode (DE-588)4324907-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Superantigen (DE-588)4312998-5 s Untersuchungsmethode (DE-588)4324907-3 s DE-604 Krakauer, Teresa edt Erscheint auch als Druck-Ausgabe 9780896039841 https://doi.org/10.1385/1592593674 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Superantigen Protocols Biomedicine Immunology Medicine Superantigen (DE-588)4312998-5 gnd Untersuchungsmethode (DE-588)4324907-3 gnd |
| subject_GND | (DE-588)4312998-5 (DE-588)4324907-3 (DE-588)4143413-4 |
| title | Superantigen Protocols |
| title_auth | Superantigen Protocols |
| title_exact_search | Superantigen Protocols |
| title_full | Superantigen Protocols edited by Teresa Krakauer |
| title_fullStr | Superantigen Protocols edited by Teresa Krakauer |
| title_full_unstemmed | Superantigen Protocols edited by Teresa Krakauer |
| title_short | Superantigen Protocols |
| title_sort | superantigen protocols |
| topic | Biomedicine Immunology Medicine Superantigen (DE-588)4312998-5 gnd Untersuchungsmethode (DE-588)4324907-3 gnd |
| topic_facet | Biomedicine Immunology Medicine Superantigen Untersuchungsmethode Aufsatzsammlung |
| url | https://doi.org/10.1385/1592593674 |
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