Drug Safety Evaluation: Methods and Protocols
Non-clinical drug safety evaluation, the assessment of the safety profile of therapeutic agents through the conduct of laboratory studies in in vitro systems and in animals, is an essential step in the progress of new pharmaceuticals heading toward the ultimate goal of clinical trials and, eventuall...
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| Other Authors: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2011
|
| Series: | Methods in Molecular Biology, Methods and Protocols
691 |
| Subjects: | |
| Online Access: | UBR01 TUM01 Volltext |
| Summary: | Non-clinical drug safety evaluation, the assessment of the safety profile of therapeutic agents through the conduct of laboratory studies in in vitro systems and in animals, is an essential step in the progress of new pharmaceuticals heading toward the ultimate goal of clinical trials and, eventually, approval. In Drug Safety Evaluation: Methods and Protocols, expert researchers detail a compendium of analytical technologies with a focus on clarity and applicability in real life laboratory practice. These meticulous contributions feature key topics such as acute to chronic general toxicity studies, histopathology studies, reproductive toxicity studies, genotoxicity studies, safety pharmacology studies, investigative toxicity studies, and safety biomarker studies. As a volume in the highly successful Methods in Molecular Biology™ series, chapters include brief introductions to their respective subjects, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Drug Safety Evaluation: Methods and Protocols serves as an ideal guide to this field, helpful to pharmaceutical scientists, toxicologists, biochemists, and molecular biologists as well as scientists from all other disciplines who wish to translate these thorough methods into their own work |
| Physical Description: | 1 Online-Ressource (XIII, 431 p. 78 illus., 4 illus. in color) |
| ISBN: | 9781607618492 |
| DOI: | 10.1007/978-1-60761-849-2 |
Staff View
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| spelling | Drug Safety Evaluation Methods and Protocols edited by Jean-Charles Gautier Totowa, NJ Humana Press 2011 1 Online-Ressource (XIII, 431 p. 78 illus., 4 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 691 Non-clinical drug safety evaluation, the assessment of the safety profile of therapeutic agents through the conduct of laboratory studies in in vitro systems and in animals, is an essential step in the progress of new pharmaceuticals heading toward the ultimate goal of clinical trials and, eventually, approval. In Drug Safety Evaluation: Methods and Protocols, expert researchers detail a compendium of analytical technologies with a focus on clarity and applicability in real life laboratory practice. These meticulous contributions feature key topics such as acute to chronic general toxicity studies, histopathology studies, reproductive toxicity studies, genotoxicity studies, safety pharmacology studies, investigative toxicity studies, and safety biomarker studies. As a volume in the highly successful Methods in Molecular Biology™ series, chapters include brief introductions to their respective subjects, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Drug Safety Evaluation: Methods and Protocols serves as an ideal guide to this field, helpful to pharmaceutical scientists, toxicologists, biochemists, and molecular biologists as well as scientists from all other disciplines who wish to translate these thorough methods into their own work Biomedicine Pharmacology/Toxicology Laboratory Medicine Medicine Laboratory medicine Pharmacology Arzneimittelsicherheit (DE-588)4143182-0 gnd rswk-swf Arzneimittelsicherheit (DE-588)4143182-0 s 1\p DE-604 Gautier, Jean-Charles edt Erscheint auch als Druck-Ausgabe 9781603271868 https://doi.org/10.1007/978-1-60761-849-2 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
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| subject_GND | (DE-588)4143182-0 |
| title | Drug Safety Evaluation Methods and Protocols |
| title_auth | Drug Safety Evaluation Methods and Protocols |
| title_exact_search | Drug Safety Evaluation Methods and Protocols |
| title_full | Drug Safety Evaluation Methods and Protocols edited by Jean-Charles Gautier |
| title_fullStr | Drug Safety Evaluation Methods and Protocols edited by Jean-Charles Gautier |
| title_full_unstemmed | Drug Safety Evaluation Methods and Protocols edited by Jean-Charles Gautier |
| title_short | Drug Safety Evaluation |
| title_sort | drug safety evaluation methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Pharmacology/Toxicology Laboratory Medicine Medicine Laboratory medicine Pharmacology Arzneimittelsicherheit (DE-588)4143182-0 gnd |
| topic_facet | Biomedicine Pharmacology/Toxicology Laboratory Medicine Medicine Laboratory medicine Pharmacology Arzneimittelsicherheit |
| url | https://doi.org/10.1007/978-1-60761-849-2 |
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