Cell polarity in development and disease:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
London ; San Diego, CA ; Cambridge, MA ; Oxford
Academic Press
[2018]
|
| Schriftenreihe: | Perspectives in translational cell biology
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | xviii, 218 Seiten Illustrationen |
| ISBN: | 9780128024386 |
Internformat
MARC
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| 245 | 1 | 0 | |a Cell polarity in development and disease |c volume editor: Douglas W. Houston |
| 264 | 1 | |a London ; San Diego, CA ; Cambridge, MA ; Oxford |b Academic Press |c [2018] | |
| 300 | |a xviii, 218 Seiten |b Illustrationen | ||
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| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Perspectives in translational cell biology | |
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Datensatz im Suchindex
| _version_ | 1807322302310776832 |
|---|---|
| adam_text |
Contents
List of Contributors ix
Editor's Foreword xi
Preface: Defining Polarity xiii
1. Cell Polarity in Oocyte Development
Denise Oh, Douglas W. Houston
Introduction 1
Oogenesis and the Establishment of Animal—Vegetal Polarity 3
Origin of Animal—Vegetal Polarity During Oogenesis 6
Xenopus 8
Zebrafish 8
Mouse 9
Polarity and the Ovarian Stem Cell 10
Structural Basis for Mitochondrial Cloud/Balbiani Formation 11
Macf 1 12
Buckyball 12
Generation of Cortical Polarity in the Oocyte and Egg 14
Cortical Polarity and Sperm Entry 1 5
Apical—Basal Polarization of the Xenopus Egg 16
Cortical Polarity and Superficial Cell Fate 17
Concluding Remarks 1 9
Acknowledgments 20
References 20
2. Pluripotency—What Does Cell Polarity Have to
Do With It?
Tristan Frum, Amy Ralston
Mammalian Pluripotency 31
Cell Polarity in the Mammalian Embryo 33
The Emergence of Pluripotency in the Mouse Embryo 33
Cel! Polarity in the Mammalian Early Embryo 38
How Cell Polarity Regulates Establishment of Pluripotency
in the Mouse Embryo 43
v
47
48
49
50
51
51
52
61
61
63
64
65
66
72
76
78
81
82
82
84
85
85
87
89
89
91
91
103
106
106
107
Contents
Cell Polarity and Embryo-Derived Pluripotent Stem Cell Lines
Multiple States of Pi unpotency
Polarization of Pluripotent Stem Cell Lines
Cell Polarization During Somatic Cell Reprogramming
Conclusions
Acknowledgments
References
Cell Polarity and Asymmetric Cell Division by
the Wnt Morphogen
Austin T. Baldwin, Bryan T. Phillips
Introduction
Binary Cell Fate Specification via Asymmetric Cell Division
PAR Proteins Polarize Caenorhabditis elegans Zygotes
Delta/Notch Signaling Drives Asymmetric Cell Division
in Fly Neuroblasts
Morphogens as Cell Polarizers
Wnt/p-Catenin Signal Transduction
Wnt/p-Catenin Asymmetry and Asymmetric Cell Division
in Caenorhabditis elegans
The Caenorhabditis elegans Epidermal Seam Stem Cell
Lineage Undergoes Reiterative Asymmetric Cell Divisions
Asymmetric Cell Divisions in the Caenorhabditis elegans
Seam Require Wnt Signaling
SYS-1/p-Catenin Inheritance Is Limited by Centrosomal
Degradation
Caenorhabditis elegans/Asymmetric Cell Division-Specific
Phenomena
PRY-1/Axin Is Upstream of the Destruction Complex
KIN-19 Versus GSK-3 Function in p-Catenin Regulation
The Future of Wnt/p-Catenin and Asymmetric Cell Division
APR-1 as the Key Regulator of Differential WpA Outputs
Dishevelled Balances Wnt/P-Catenin Asymmetry Outputs
Wnt Ligands and Receptors
Concluding Remarks
Acknowledgments
References
Cell Polarity in Morphogenesis—Planar Cell Polarity
Noopur Mandrekar, Baihao Su, Raymond Habas
Introduction
The Planar Cell Polarity Pathway
Wnts
Asymmetric Protein Localization: From Flies to Vertebrates
Contents vii
Role of Cytoskeletal Components During Castrulation 111
Actin 111
Microtubules 112
Planar Cell Polarity Regulation: Cross Talk Between
Cytoskeletal Components 113
Planar Cell Polarity in Vertebrates 113
Conclusions 114
References 115
5. Polarized Membrane Trafficking in Development
and Disease: From Epithelia Polarization to Cancer
Cell Invasion
Erik Linklater, Cayla E. Jewett, Rytis Prekeris
Introduction 121
Epithelial Polarity and Lumen Formation 122
Membrane Transport and Polarization of Individual
Epithelial Cells 122
Polarized Membrane Transport and Apical Lumen Formation
During Epithelial Tissue Morphogenesis 125
Regulation of De Novo Lumen Formation In Vivo 128
Polarized Membrane Transport During Cancer Metastasis
and Development 130
Podosomes and Cell Migration 130
Invadopodia and Cancer Cell Metastasis 132
Membrane Transport and MMP Targeting During Invadopodia
Formation 134
Concluding Remarks 138
Acknowledgments 139
References 139
6. Planar Cell Polarity and the Cell Biology of Nervous
System Development and Disease
J. Robert Manak
Introduction 147
Breaking the Rules 149
Effectors of Planar Cell Polarity Genes 150
Axonal Determination/Polarization: Connections to
Polarity Genes 150
Planar Cell Polarity Mutants Exhibit Axonal Extension Defects 1 53
Axonal Extension and the Dynamics of the Cytoskeleton 1 54
Lamellipodia and Filopodia Use Different Actin Nucleators 1 56
Neuronal Cell Migration Uses the Same Players as During
Axonal Polarization 157
Contents
The Adherens Junction: A Convergence of Interdependent
Signaling Complexes 158
Focal Adhesions: Reinventing the Adherens Junction for
Cellular Movement and Migration 166
Convergence Extension Defects Leading to Open
Neural Tube 1 68
Conclusions 168
Acknowledgments 169
References 169
7. Planar Cell Polarity in Ciliated Epithelia
Peter Walentek, Camille Boutin, Laurent Kodjabachian
Introduction 177
Initiation and Coordination of Tissue-Level Planar Polarity in
Ciliated Epithelia 181
Xenopus Embryonic Epidermis 181
Mouse Trachea 187
Mouse Ependyma 188
Transmission of Planar Cell Polarity to Basal Bodies in
Multiciliated Cells 191
The Xenopus Mucociliary Epidermis 192
Mouse Trachea 196
Mouse Ependyma 197
Future Challenges 200
General Conclusion 202
Acknowledgments 202
References 203
Index 211 |
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| spelling | Cell polarity in development and disease volume editor: Douglas W. Houston London ; San Diego, CA ; Cambridge, MA ; Oxford Academic Press [2018] xviii, 218 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Perspectives in translational cell biology Entwicklung (DE-588)4113450-3 gnd rswk-swf Polarität (DE-588)4126483-6 gnd rswk-swf Krankheit (DE-588)4032844-2 gnd rswk-swf Zelle (DE-588)4067537-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Zelle (DE-588)4067537-3 s Polarität (DE-588)4126483-6 s Entwicklung (DE-588)4113450-3 s DE-604 Krankheit (DE-588)4032844-2 s Houston, Douglas W. (DE-588)1147297037 edt Erscheint auch als Online-Ausgabe 978-0-12-812591-5 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030312960&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Cell polarity in development and disease Entwicklung (DE-588)4113450-3 gnd Polarität (DE-588)4126483-6 gnd Krankheit (DE-588)4032844-2 gnd Zelle (DE-588)4067537-3 gnd |
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| title | Cell polarity in development and disease |
| title_auth | Cell polarity in development and disease |
| title_exact_search | Cell polarity in development and disease |
| title_full | Cell polarity in development and disease volume editor: Douglas W. Houston |
| title_fullStr | Cell polarity in development and disease volume editor: Douglas W. Houston |
| title_full_unstemmed | Cell polarity in development and disease volume editor: Douglas W. Houston |
| title_short | Cell polarity in development and disease |
| title_sort | cell polarity in development and disease |
| topic | Entwicklung (DE-588)4113450-3 gnd Polarität (DE-588)4126483-6 gnd Krankheit (DE-588)4032844-2 gnd Zelle (DE-588)4067537-3 gnd |
| topic_facet | Entwicklung Polarität Krankheit Zelle Aufsatzsammlung |
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