Stochastic resonance as a putative cause of subjectve tinnitus: = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus
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| Main Author: | |
|---|---|
| Format: | Thesis Book |
| Language: | English |
| Published: |
Erlangen ; Nürnberg
[2018]
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis Inhaltsverzeichnis |
| Physical Description: | XII, 109 Seiten Illustrationen, Diagramme 21 cm |
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| 245 | 1 | 0 | |a Stochastic resonance as a putative cause of subjectve tinnitus |b = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus |c vorgelegt von Patrick Krauß |
| 246 | 1 | 3 | |a Stochastic resonance as a putative cause of subjective tinnitus |
| 246 | 1 | 1 | |a Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus |
| 264 | 1 | |a Erlangen ; Nürnberg |c [2018] | |
| 300 | |a XII, 109 Seiten |b Illustrationen, Diagramme |c 21 cm | ||
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| 502 | |b Dissertation |c Friedrich-Alexander-Universität Erlangen-Nürnberg |d 2018 | ||
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Record in the Search Index
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| adam_text | C ONTENTS
DANKSAGUNG I
KURZFASSUNG III
ABSTRACT VI
1 INTRODUCTION 1
1.1 SUBJECTIVE T IN N ITU
S.............................................................................................
1
1.2 LATERAL (DIS-)INHIBITION M O D E LS
.......................................................................
2
1.3 CENTRAL GAIN OR HOMEOSTATIC PLASTICITY MODELS
...............................................
2
1.4 STOCHASTIC RESONANCE
.........................................................................................
3
1.5 ADAPTIVE STOCHASTIC RESONANCE
.......................................................................
5
1.6 ADAPTIVE STOCHASTIC RESONANCE BASED ON OUTPUT AUTOCORRELATIONS
..............
6
1.7 STOCHASTIC RESONANCE AS A PUTATIVE CAUSE OF SUBJECTIVE T
INNITUS................ 6
2 METHODS 9
2.1 DATA ACQUISITION AND V
ISUALIZATION..................................................................
9
2.1.1 PATIENT DATA
.........................................................................................
9
2.1.2 ANIMAL M
ODEL.........................................................................................
9
2.1.3 INDUCTION OF ACOUSTIC T RA U M A
.............................................................. 10
2.1.4 ASSESSMENT OF HEARING THRESHOLDS IN THE ANIMAL
MODEL.................... 10
2.1.5 TINNITUS ASSESSMENT IN THE ANIMAL M O D E L
........................................
12
2.1.6 S U R G E R Y
...................................................................................................
14
2.1.7 ELECTROPHYSIOLOGICAL RECORDINGS OF CORTICAL LOCAL FIELD POTENTIALS
( L F P )
................................................................... 16
2.1.8 VISUALIZATION OF CORTICAL RECORDINGS WITH MULTIDIMENSIONAL SCALING
17
2.2 NUMERICAL S IM U LATIO N
S........................................................................................
17
2.2.1 MUTUAL INFORM
ATION.................................................................................
17
2.2.2 OUTPUT AUTOCORRELATION
.......................................................................
18
2.2.3 INPUT SIGNALS FOR ADAPTIVE STOCHASTIC RESONANCE
...............................
18
2.2.4 SENSOR MODELS FOR ADAPTIVE STOCHASTIC R ESONANCE
............................
19
2.2.5 DISTRIBUTION OF SOUND INTENSITIES OF ACOUSTIC STIMULI
......................
20
2.2.6 MODELING OF AUDITORY NERVE R
ESPONSES............................................... 20
3 RESULTS 23
3.1
OVERVIEW................................................................................................................
23
3.2 ANIMAL MODEL OF SUBJECTIVE T IN N ITU S
.............................................................. 25
3.2.1 ACOUSTIC TRAUMA INDUCED HEARING L O
SS............................................... 25
3.2.2 BEHAVIORAL SIGNS OF T IN N ITU
S................................................................. 25
3.2.3 TINNITUS-RELATED NEURONAL H
YPERACTIVITY............................................ 26
3.3 ADAPTIVE STOCHASTIC RESONANCE BASED ON OUTPUT
AUTOCORRELATIONS................ 28
3.3.1 SIMPLIFIED MODEL S Y STE M
.......................................................................
29
3.3.2 DEFINITION OF SUCCESS
PROBABILITY...........................................................
29
3.3.3 PROOF OF THE EQUIVALENCE OF MUTUAL INFORMATION AND OUTPUT AUTO
CORRELATION IN THE SIMPLIFIED MODEL S Y STE M
........................................
29
3.3.4 DERIVATION OF SUCCESS PROBABILITY IN THE SIMPLIFIED MODEL SYSTEM .
31
3.3.5 DERIVATION OF MUTUAL INFORMATION IN THE SIMPLIFIED MODEL SYSTEM .
33
3.3.6 DERIVATION OF O UTPUT AUTOCORRELATION IN THE SIMPLIFIED MODEL
SYSTEM 34
3.3.7 GENERALIZATION TO DIFFERENT INPUT SIGNALS, DETECTOR MODELS AND
THRESH
OLD L E V E LS
................................................................................................
37
3.3.8 GENERALIZATION TO DETECTORS WITH SOFT THRESHOLDS AND NON-GAUSSIAN
N
OISE.........................................................................................................
41
3.3.9 DIFFERENT TYPES OF DETECTORS AND MULTIPLICATIVE N O ISE
...................... 42
3.4 STOCHASTIC RESONANCE AS A PUTATIVE CAUSE OF SUBJECTIVE T INNITUS
....................
44
3.4.1 PHENOMENOLOGICAL MODEL OF TINNITUS-RELATED NEURONAL HYPERACTIVITY
46
3.4.2 UP-REGULATION OF INTERNAL NOISE AS A CORRELATE OF TINNITUS-RELATED
NEURONAL H YPERACTIVITY
..........................................................................
47
3.4.3 STOCHASTIC RESONANCE IMPROVES DETECTION PROBABILITY AFTER HEARING
L O S S
.........................................................................................................
47
3.4.4 REDUCED INPUT DECREASES THE MEAN AUTOCORRELATION FUNCTION OF THE
SENSOR O U TP U
T..........................................................................................
48
3.4.5 STOCHASTIC RESONANCE IMPROVES MEAN AUTOCORRELATION AND INCREASES
INTERNAL NOISE AFTER HEARING L O S S
........................................................ 49
3.5 AUDIOMETRIC PATIENT DATA IN SUPPORT OF THE
HYPOTHESIS................................. 52
3.6 A NEW EXPERIMENTAL PARADIGM TO SIMULATE TRANSIENT HEARING LOSS ....
54
3.6.1 LONG-TERM DIPPED NOISE E X P O SU RE
..................................................... 54
3.6.2 LONG-TERM DIPPED NOISE EXPOSURE IMPROVES HEARING THRESHOLDS. . 56
3.6.3 LONG-TERM DIPPED NOISE EXPOSURE INDUCES BEHAVIORAL SIGNS OF TIN
NITUS...........................................................................................................
56
3.7 IN SEARCH OF THE NEUROPHYSIOLOGICAL CORRELATE OF PERCEPTION
.............................
60
3.7.1 A NEW STATISTICAL METHOD TO COMPARE CLUSTERS OF DATA POINTS IN
HIGH-DIMENSIONAL S P A C E
.......................................................................
61
3.7.2 ANALYSIS OF STEADY-STATE LOCAL FIELD POTENTIAL DATA FROM GERBIL
AUDITORY CORTEX
...................................................................................
67
4 DISCUSSION 73
4.1 PLAUSIBILITY OF THE MODEL IN THE CONTEXT OF THE ANATOMY OF THE
AUDITORY
S YSTEM
..................................................................................................................
75
4.2 NEURONAL HYPERACTIVITY WITHIN THE AUDITORY SYSTEM AS A POSSIBLE
CORRELATE
FOR AUDITORY PHANTOM P E RC E P TS
.......................................................................
81
LIST OF PUBLICATIONS 85
LIST OF FIGURES 89
REFERENCES 91
|
| any_adam_object | 1 |
| author | Krauß, Patrick |
| author_facet | Krauß, Patrick |
| author_role | aut |
| author_sort | Krauß, Patrick |
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| building | Verbundindex |
| bvnumber | BV044862689 |
| ctrlnum | (OCoLC)1136446401 (DE-599)DNB1153803631 |
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| format | Thesis Book |
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| indexdate | 2024-07-10T08:03:10Z |
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| language | English |
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| physical | XII, 109 Seiten Illustrationen, Diagramme 21 cm |
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| spelling | Krauß, Patrick Verfasser aut Stochastic resonance as a putative cause of subjectve tinnitus = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus vorgelegt von Patrick Krauß Stochastic resonance as a putative cause of subjective tinnitus Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus Erlangen ; Nürnberg [2018] XII, 109 Seiten Illustrationen, Diagramme 21 cm txt rdacontent n rdamedia nc rdacarrier Dissertation Friedrich-Alexander-Universität Erlangen-Nürnberg 2018 Stochastische Resonanz (DE-588)4678002-6 gnd rswk-swf Ursache (DE-588)4062163-7 gnd rswk-swf Ohrgeräusch (DE-588)4121423-7 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Stochastische Resonanz (DE-588)4678002-6 s Ursache (DE-588)4062163-7 s Ohrgeräusch (DE-588)4121423-7 s DE-604 B:DE-101 application/pdf http://d-nb.info/1153803631/04 Inhaltsverzeichnis DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030257329&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Krauß, Patrick Stochastic resonance as a putative cause of subjectve tinnitus = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus Stochastische Resonanz (DE-588)4678002-6 gnd Ursache (DE-588)4062163-7 gnd Ohrgeräusch (DE-588)4121423-7 gnd |
| subject_GND | (DE-588)4678002-6 (DE-588)4062163-7 (DE-588)4121423-7 (DE-588)4113937-9 |
| title | Stochastic resonance as a putative cause of subjectve tinnitus = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus |
| title_alt | Stochastic resonance as a putative cause of subjective tinnitus Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus |
| title_auth | Stochastic resonance as a putative cause of subjectve tinnitus = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus |
| title_exact_search | Stochastic resonance as a putative cause of subjectve tinnitus = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus |
| title_full | Stochastic resonance as a putative cause of subjectve tinnitus = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus vorgelegt von Patrick Krauß |
| title_fullStr | Stochastic resonance as a putative cause of subjectve tinnitus = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus vorgelegt von Patrick Krauß |
| title_full_unstemmed | Stochastic resonance as a putative cause of subjectve tinnitus = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus vorgelegt von Patrick Krauß |
| title_short | Stochastic resonance as a putative cause of subjectve tinnitus |
| title_sort | stochastic resonance as a putative cause of subjectve tinnitus stochastische resonanz als mogliche ursache fur subjektiven tinnitus |
| title_sub | = Stochastische Resonanz als mögliche Ursache für subjektiven Tinnitus |
| topic | Stochastische Resonanz (DE-588)4678002-6 gnd Ursache (DE-588)4062163-7 gnd Ohrgeräusch (DE-588)4121423-7 gnd |
| topic_facet | Stochastische Resonanz Ursache Ohrgeräusch Hochschulschrift |
| url | http://d-nb.info/1153803631/04 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030257329&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT kraußpatrick stochasticresonanceasaputativecauseofsubjectvetinnitusstochastischeresonanzalsmoglicheursachefursubjektiventinnitus AT kraußpatrick stochasticresonanceasaputativecauseofsubjectivetinnitus AT kraußpatrick stochastischeresonanzalsmoglicheursachefursubjektiventinnitus |
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