Computational exome and genome analysis:
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Boca Raton ; London ; New York
CRC Press
[2018]
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| Series: | Chapman & Hall/CRC mathematical and computational biology
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Literaturverzeichnis Seite 503-545 |
| Physical Description: | xxi, 552 Seiten Diagramme |
| ISBN: | 9781498775984 |
Staff View
MARC
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Record in the Search Index
| _version_ | 1804178164886274048 |
|---|---|
| adam_text | Contents
Preface XV
Contributors xxi
Part 1 Introduction
Chapter 1 ■ Introduction 3
Chapter 2 ■ NGS Technology 11
Chapter 3 ■ lllumina Technology 21
Chapter 4 ■ Data 47
Part II Raw Data Processing
Chapter 5■FASTQ 57
Chapter 6 ■ Q/C: Raw Data 67
Chapter 7 ■ Q/C: Trimming 81
Part III Alignment
Chapter 8 ■ Alignment 95
Chapter 9 ■ SAM/BAM 111
IX
x ■ Contents
Chapter 10· Postprocessing the Alignment 129
Chapter 11· Alignment Data: Quality Control 149
Part IV Variant Calling
Chapter 12· Variant Calling Quality-Based Filtering 163
Chapter 13· VCF 183
Chapter 14· Jannovar 203
Chapter 15· Variant Annotation 209
Chapter 16 · Variant Calling QC 229
Chapter 17· Integrative Genomics Viewer 233
Chapter 18· De Novo Variants 247
Chapter 19· Structural Variation 259
Part V Variant Filtering______________________________________
Oi A i TKH 20 ■ Pedigree Analysis 297
Chapter21 ■ Intersection and RVAS Analysis 315
Chapter 22 ■ Variant Frequency 321
Chapter 23 ■ Variant Pathogenicity 329
Part VI Prioritization
Chapter 24 ■ Prioritization 349
Chapter 25 ■ Random Walk
355
Contents ■ xi
Chapter 26 ■ Phenotype Analysis 367
Chapter 27 ■ Exomiser 387
Chapter 28 ■ Medical Interpretation 407
Part VII Cancer
Chapter 29 ■ A (Very) Short Introduction to Cancer 419
Chapter 30 ■ Somatic Variants 429
Chapter 31 ■ Tumor Evolution and Sample Purity 467
Chapter 32 ■ Driver Mutations and Mutational Signatures 477
Appendix A ■ Hints and Answers 499
References 503
Index
547
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| dewey-tens | 570 - Biology |
| discipline | Biologie |
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| id | DE-604.BV044697608 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:59:38Z |
| institution | BVB |
| isbn | 9781498775984 |
| language | English |
| lccn | 017019188 |
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| physical | xxi, 552 Seiten Diagramme |
| publishDate | 2018 |
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| spelling | Robinson, Peter N. Verfasser aut Computational exome and genome analysis Peter N. Robinson, Rosario M. Piro, Marten Jäger Boca Raton ; London ; New York CRC Press [2018] xxi, 552 Seiten Diagramme txt rdacontent n rdamedia nc rdacarrier Chapman & Hall/CRC mathematical and computational biology Literaturverzeichnis Seite 503-545 Exome Genome Computational Biology Sequence Analysis, DNA Bioinformatik (DE-588)4611085-9 gnd rswk-swf Computerunterstütztes Verfahren (DE-588)4139030-1 gnd rswk-swf Genanalyse (DE-588)4200230-8 gnd rswk-swf Genanalyse (DE-588)4200230-8 s Computerunterstütztes Verfahren (DE-588)4139030-1 s Bioinformatik (DE-588)4611085-9 s DE-604 Piro, Rosario M. Verfasser aut Jäger, Marten Verfasser aut Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030094415&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Robinson, Peter N. Piro, Rosario M. Jäger, Marten Computational exome and genome analysis Exome Genome Computational Biology Sequence Analysis, DNA Bioinformatik (DE-588)4611085-9 gnd Computerunterstütztes Verfahren (DE-588)4139030-1 gnd Genanalyse (DE-588)4200230-8 gnd |
| subject_GND | (DE-588)4611085-9 (DE-588)4139030-1 (DE-588)4200230-8 |
| title | Computational exome and genome analysis |
| title_auth | Computational exome and genome analysis |
| title_exact_search | Computational exome and genome analysis |
| title_full | Computational exome and genome analysis Peter N. Robinson, Rosario M. Piro, Marten Jäger |
| title_fullStr | Computational exome and genome analysis Peter N. Robinson, Rosario M. Piro, Marten Jäger |
| title_full_unstemmed | Computational exome and genome analysis Peter N. Robinson, Rosario M. Piro, Marten Jäger |
| title_short | Computational exome and genome analysis |
| title_sort | computational exome and genome analysis |
| topic | Exome Genome Computational Biology Sequence Analysis, DNA Bioinformatik (DE-588)4611085-9 gnd Computerunterstütztes Verfahren (DE-588)4139030-1 gnd Genanalyse (DE-588)4200230-8 gnd |
| topic_facet | Exome Genome Computational Biology Sequence Analysis, DNA Bioinformatik Computerunterstütztes Verfahren Genanalyse |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030094415&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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