The ubiquitin-proteasome proteolytic system: from classical biochemistry to human diseases
Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, which includes: the cell cycle; cell growth and differentiation; embryogenesis; apoptosis; signal transduction; DNA repair; regulation of transcription and DNA replication; transmembrane...
Saved in:
| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
Singapore
World Scientific Pub. Co.
c2002
|
| Series: | Recent advances in human biology
v. 9 |
| Subjects: | |
| Online Access: | FHN01 Volltext |
| Summary: | Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, which includes: the cell cycle; cell growth and differentiation; embryogenesis; apoptosis; signal transduction; DNA repair; regulation of transcription and DNA replication; transmembrane transport; endocytosis; stress responses; antigen presentation and other aspects of the immune response; the functions of the nervous system including circadian rhythms; axon guidance and acquisition of memory. This book tells the story of the ubiquitin system as we currently know it: from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, from X-ray crystallography of the 26S proteasome to the interaction between substrates and their ligases, to the development of mechanism-based drugs, and to target-specific aberrant processes |
| Physical Description: | xx, 220 p. ill |
| ISBN: | 9789812776877 |
Staff View
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| id | DE-604.BV044635107 |
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| indexdate | 2024-07-10T07:57:46Z |
| institution | BVB |
| isbn | 9789812776877 |
| language | English |
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| physical | xx, 220 p. ill |
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| series2 | Recent advances in human biology |
| spelling | The ubiquitin-proteasome proteolytic system from classical biochemistry to human diseases editors, Aaron J. Ciechanover, Maria G. Masucci Singapore World Scientific Pub. Co. c2002 xx, 220 p. ill txt rdacontent c rdamedia cr rdacarrier Recent advances in human biology v. 9 Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, which includes: the cell cycle; cell growth and differentiation; embryogenesis; apoptosis; signal transduction; DNA repair; regulation of transcription and DNA replication; transmembrane transport; endocytosis; stress responses; antigen presentation and other aspects of the immune response; the functions of the nervous system including circadian rhythms; axon guidance and acquisition of memory. This book tells the story of the ubiquitin system as we currently know it: from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, from X-ray crystallography of the 26S proteasome to the interaction between substrates and their ligases, to the development of mechanism-based drugs, and to target-specific aberrant processes Ubiquitin Proteolytic enzymes Proteins / Metabolism Ciechanover, Aaron J. Sonstige oth Masucci, Maria G. Sonstige oth Erscheint auch als Druck-Ausgabe 9789812381002 Erscheint auch als Druck-Ausgabe 9812381007 http://www.worldscientific.com/worldscibooks/10.1142/5051#t=toc Verlag URL des Erstveroeffentlichers Volltext |
| spellingShingle | The ubiquitin-proteasome proteolytic system from classical biochemistry to human diseases Ubiquitin Proteolytic enzymes Proteins / Metabolism |
| title | The ubiquitin-proteasome proteolytic system from classical biochemistry to human diseases |
| title_auth | The ubiquitin-proteasome proteolytic system from classical biochemistry to human diseases |
| title_exact_search | The ubiquitin-proteasome proteolytic system from classical biochemistry to human diseases |
| title_full | The ubiquitin-proteasome proteolytic system from classical biochemistry to human diseases editors, Aaron J. Ciechanover, Maria G. Masucci |
| title_fullStr | The ubiquitin-proteasome proteolytic system from classical biochemistry to human diseases editors, Aaron J. Ciechanover, Maria G. Masucci |
| title_full_unstemmed | The ubiquitin-proteasome proteolytic system from classical biochemistry to human diseases editors, Aaron J. Ciechanover, Maria G. Masucci |
| title_short | The ubiquitin-proteasome proteolytic system |
| title_sort | the ubiquitin proteasome proteolytic system from classical biochemistry to human diseases |
| title_sub | from classical biochemistry to human diseases |
| topic | Ubiquitin Proteolytic enzymes Proteins / Metabolism |
| topic_facet | Ubiquitin Proteolytic enzymes Proteins / Metabolism |
| url | http://www.worldscientific.com/worldscibooks/10.1142/5051#t=toc |
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