Transporters as Drug Targets:
As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacolog...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Weinheim, Germany
Wiley-VCH
© 2017
|
| Schriftenreihe: | Methods and principles in medicinal chemistry
v. 70 |
| Schlagworte: | |
| Online-Zugang: | DE-861 DE-473 Volltext |
| Zusammenfassung: | As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease |
| Beschreibung: | 1 online resource |
| ISBN: | 9783527679430 352767943X 3527679510 9783527679522 3527679529 9783527679515 |
Internformat
MARC
| LEADER | 00000nmm a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV044442420 | ||
| 003 | DE-604 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 170808s2017 |||| o||u| ||||||eng d | ||
| 020 | |a 9783527679430 |9 978-3-527-67943-0 | ||
| 020 | |a 352767943X |9 3-527-67943-X | ||
| 020 | |a 3527679510 |9 3-527-67951-0 | ||
| 020 | |a 9783527679522 |9 978-3-527-67952-2 | ||
| 020 | |a 3527679529 |9 3-527-67952-9 | ||
| 020 | |a 9783527679515 |9 978-3-527-67951-5 | ||
| 024 | 7 | |a 10.1002/9783527679430 |2 doi | |
| 035 | |a (ZDB-35-WIC)967084849 | ||
| 035 | |a (OCoLC)967084849 | ||
| 035 | |a (DE-599)BVBBV044442420 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-861 | ||
| 082 | 0 | |a 572/.696 |2 23 | |
| 245 | 1 | 0 | |a Transporters as Drug Targets |
| 264 | 1 | |a Weinheim, Germany |b Wiley-VCH |c © 2017 | |
| 300 | |a 1 online resource | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Methods and principles in medicinal chemistry |v v. 70 | |
| 520 | |a As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease | ||
| 650 | 7 | |a SCIENCE / Life Sciences / Biochemistry |2 bisacsh | |
| 650 | 7 | |a Carrier proteins |2 fast | |
| 650 | 7 | |a Drug targeting |2 fast | |
| 650 | 4 | |a Drug Carriers | |
| 650 | 4 | |a Carrier proteins | |
| 650 | 4 | |a Drug targeting | |
| 650 | 0 | 7 | |a Arzneistoffträger |0 (DE-588)4278196-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a ABC-Transporter |0 (DE-588)4472594-2 |2 gnd |9 rswk-swf |
| 655 | 7 | |8 1\p |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Arzneistoffträger |0 (DE-588)4278196-6 |D s |
| 689 | 0 | 1 | |a ABC-Transporter |0 (DE-588)4472594-2 |D s |
| 689 | 0 | |8 2\p |5 DE-604 | |
| 700 | 1 | |a Ecker, Gerhard F. |4 edt | |
| 700 | 1 | |a Clausen, Rasmus P. |e Sonstige |4 oth | |
| 700 | 1 | |a Sitte, Harald |e Sonstige |4 oth | |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/book/10.1002/9783527679430 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 883 | 1 | |8 2\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 912 | |a ZDB-35-WIC | ||
| 940 | 1 | |q UBG_PDA_WIC | |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-029843552 | |
| 966 | e | |u https://onlinelibrary.wiley.com/doi/book/10.1002/9783527679430 |l DE-861 |p ZDB-35-WIC |q FRO_PDA_WIC |x Verlag |3 Volltext | |
| 966 | e | |u https://onlinelibrary.wiley.com/doi/book/10.1002/9783527679430 |l DE-473 |p ZDB-35-WIC |q UBG_PDA_WIC |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1805086999314432000 |
|---|---|
| adam_text | |
| any_adam_object | |
| author2 | Ecker, Gerhard F. |
| author2_role | edt |
| author2_variant | g f e gf gfe |
| author_facet | Ecker, Gerhard F. |
| building | Verbundindex |
| bvnumber | BV044442420 |
| collection | ZDB-35-WIC |
| ctrlnum | (ZDB-35-WIC)967084849 (OCoLC)967084849 (DE-599)BVBBV044442420 |
| dewey-full | 572/.696 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572/.696 |
| dewey-search | 572/.696 |
| dewey-sort | 3572 3696 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nmm a2200000zcb4500</leader><controlfield tag="001">BV044442420</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">170808s2017 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783527679430</subfield><subfield code="9">978-3-527-67943-0</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">352767943X</subfield><subfield code="9">3-527-67943-X</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3527679510</subfield><subfield code="9">3-527-67951-0</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783527679522</subfield><subfield code="9">978-3-527-67952-2</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3527679529</subfield><subfield code="9">3-527-67952-9</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783527679515</subfield><subfield code="9">978-3-527-67951-5</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1002/9783527679430</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-35-WIC)967084849</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)967084849</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044442420</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-861</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">572/.696</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Transporters as Drug Targets</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Weinheim, Germany</subfield><subfield code="b">Wiley-VCH</subfield><subfield code="c">© 2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods and principles in medicinal chemistry</subfield><subfield code="v">v. 70</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">SCIENCE / Life Sciences / Biochemistry</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Carrier proteins</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Drug targeting</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drug Carriers</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Carrier proteins</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drug targeting</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Arzneistoffträger</subfield><subfield code="0">(DE-588)4278196-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">ABC-Transporter</subfield><subfield code="0">(DE-588)4472594-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="8">1\p</subfield><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Arzneistoffträger</subfield><subfield code="0">(DE-588)4278196-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">ABC-Transporter</subfield><subfield code="0">(DE-588)4472594-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">2\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ecker, Gerhard F.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Clausen, Rasmus P.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sitte, Harald</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://onlinelibrary.wiley.com/doi/book/10.1002/9783527679430</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">2\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-35-WIC</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">UBG_PDA_WIC</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-029843552</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://onlinelibrary.wiley.com/doi/book/10.1002/9783527679430</subfield><subfield code="l">DE-861</subfield><subfield code="p">ZDB-35-WIC</subfield><subfield code="q">FRO_PDA_WIC</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://onlinelibrary.wiley.com/doi/book/10.1002/9783527679430</subfield><subfield code="l">DE-473</subfield><subfield code="p">ZDB-35-WIC</subfield><subfield code="q">UBG_PDA_WIC</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| genre | 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV044442420 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-20T08:45:09Z |
| institution | BVB |
| isbn | 9783527679430 352767943X 3527679510 9783527679522 3527679529 9783527679515 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029843552 |
| oclc_num | 967084849 |
| open_access_boolean | |
| owner | DE-861 |
| owner_facet | DE-861 |
| physical | 1 online resource |
| psigel | ZDB-35-WIC UBG_PDA_WIC ZDB-35-WIC FRO_PDA_WIC ZDB-35-WIC UBG_PDA_WIC |
| publishDate | 2017 |
| publishDateSearch | 2017 |
| publishDateSort | 2017 |
| publisher | Wiley-VCH |
| record_format | marc |
| series2 | Methods and principles in medicinal chemistry |
| spelling | Transporters as Drug Targets Weinheim, Germany Wiley-VCH © 2017 1 online resource txt rdacontent c rdamedia cr rdacarrier Methods and principles in medicinal chemistry v. 70 As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease SCIENCE / Life Sciences / Biochemistry bisacsh Carrier proteins fast Drug targeting fast Drug Carriers Carrier proteins Drug targeting Arzneistoffträger (DE-588)4278196-6 gnd rswk-swf ABC-Transporter (DE-588)4472594-2 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Arzneistoffträger (DE-588)4278196-6 s ABC-Transporter (DE-588)4472594-2 s 2\p DE-604 Ecker, Gerhard F. edt Clausen, Rasmus P. Sonstige oth Sitte, Harald Sonstige oth https://onlinelibrary.wiley.com/doi/book/10.1002/9783527679430 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Transporters as Drug Targets SCIENCE / Life Sciences / Biochemistry bisacsh Carrier proteins fast Drug targeting fast Drug Carriers Carrier proteins Drug targeting Arzneistoffträger (DE-588)4278196-6 gnd ABC-Transporter (DE-588)4472594-2 gnd |
| subject_GND | (DE-588)4278196-6 (DE-588)4472594-2 (DE-588)4143413-4 |
| title | Transporters as Drug Targets |
| title_auth | Transporters as Drug Targets |
| title_exact_search | Transporters as Drug Targets |
| title_full | Transporters as Drug Targets |
| title_fullStr | Transporters as Drug Targets |
| title_full_unstemmed | Transporters as Drug Targets |
| title_short | Transporters as Drug Targets |
| title_sort | transporters as drug targets |
| topic | SCIENCE / Life Sciences / Biochemistry bisacsh Carrier proteins fast Drug targeting fast Drug Carriers Carrier proteins Drug targeting Arzneistoffträger (DE-588)4278196-6 gnd ABC-Transporter (DE-588)4472594-2 gnd |
| topic_facet | SCIENCE / Life Sciences / Biochemistry Carrier proteins Drug targeting Drug Carriers Arzneistoffträger ABC-Transporter Aufsatzsammlung |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/9783527679430 |
| work_keys_str_mv | AT eckergerhardf transportersasdrugtargets AT clausenrasmusp transportersasdrugtargets AT sitteharald transportersasdrugtargets |