Polymers and nanomaterials for gene therapy:
Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable car...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Waltham, MA
Woodhead Publishing
[2016]
|
| Schriftenreihe: | Woodhead Publishing series in biomedicine
numbers 83 |
| Schlagworte: | |
| Online-Zugang: | FAW01 URL des Erstveröffentlichers |
| Zusammenfassung: | Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | 1 online resource |
| ISBN: | 9780081005217 0081005210 9780081005200 |
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| id | DE-604.BV044392288 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:51:42Z |
| institution | BVB |
| isbn | 9780081005217 0081005210 9780081005200 |
| language | English |
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| spelling | Polymers and nanomaterials for gene therapy edited by Ravin Narain Waltham, MA Woodhead Publishing [2016] © 2016 1 online resource txt rdacontent c rdamedia cr rdacarrier Woodhead Publishing series in biomedicine numbers 83 Includes bibliographical references and index Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy HEALTH & FITNESS / Holism bisacsh HEALTH & FITNESS / Reference bisacsh MEDICAL / Alternative Medicine bisacsh MEDICAL / Atlases bisacsh MEDICAL / Essays bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Holistic Medicine bisacsh MEDICAL / Osteopathy bisacsh Gene therapy fast Nanomedicine fast Polymers in medicine fast Medizin Polymers in medicine Nanomedicine Gene therapy Narain, Ravin edt http://www.sciencedirect.com/science/book/9780081005200 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Polymers and nanomaterials for gene therapy HEALTH & FITNESS / Holism bisacsh HEALTH & FITNESS / Reference bisacsh MEDICAL / Alternative Medicine bisacsh MEDICAL / Atlases bisacsh MEDICAL / Essays bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Holistic Medicine bisacsh MEDICAL / Osteopathy bisacsh Gene therapy fast Nanomedicine fast Polymers in medicine fast Medizin Polymers in medicine Nanomedicine Gene therapy |
| title | Polymers and nanomaterials for gene therapy |
| title_auth | Polymers and nanomaterials for gene therapy |
| title_exact_search | Polymers and nanomaterials for gene therapy |
| title_full | Polymers and nanomaterials for gene therapy edited by Ravin Narain |
| title_fullStr | Polymers and nanomaterials for gene therapy edited by Ravin Narain |
| title_full_unstemmed | Polymers and nanomaterials for gene therapy edited by Ravin Narain |
| title_short | Polymers and nanomaterials for gene therapy |
| title_sort | polymers and nanomaterials for gene therapy |
| topic | HEALTH & FITNESS / Holism bisacsh HEALTH & FITNESS / Reference bisacsh MEDICAL / Alternative Medicine bisacsh MEDICAL / Atlases bisacsh MEDICAL / Essays bisacsh MEDICAL / Family & General Practice bisacsh MEDICAL / Holistic Medicine bisacsh MEDICAL / Osteopathy bisacsh Gene therapy fast Nanomedicine fast Polymers in medicine fast Medizin Polymers in medicine Nanomedicine Gene therapy |
| topic_facet | HEALTH & FITNESS / Holism HEALTH & FITNESS / Reference MEDICAL / Alternative Medicine MEDICAL / Atlases MEDICAL / Essays MEDICAL / Family & General Practice MEDICAL / Holistic Medicine MEDICAL / Osteopathy Gene therapy Nanomedicine Polymers in medicine Medizin |
| url | http://www.sciencedirect.com/science/book/9780081005200 |
| work_keys_str_mv | AT narainravin polymersandnanomaterialsforgenetherapy |