Drug discovery in cancer epigenetics:

Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy predictio...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Weitere Verfasser: Egger, Gerda (HerausgeberIn), Arimondo, Paola (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Oxford Waltham, MA Academic Press, an imprint of Elsevier [2016]
Schriftenreihe:Translational epigenetics series
Schlagworte:
Online-Zugang:FAW01
URL des Erstveröffentlichers
Zusammenfassung:Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin reader proteins. The first few drugs are already FDA approved and have made their way into clinical settings. This book provides a comprehensive summary of the epigenetic drugs currently available and aims to increase awareness in this area to foster more rapid translation of epigenetic drugs into the clinic
Beschreibung:Includes bibliographical references (pages 449-456) and index
Beschreibung:1 online resource (xxi, 475 pages)
ISBN:9780128024928
0128024925
9780128022085
0128022086

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