Basic aspects of catechol-O-methyltransferase and the clinical applications of its inhibitors:
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Bibliographische Detailangaben
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Amsterdam Elsevier/Academic Press ©2010
Schriftenreihe:International review of neurobiology v. 95
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Online-Zugang:FAW01
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Beschreibung:"Since its discovery in 1958, the Catechol-O-methyltransferase (COMT) enzyme has generated a lot of excitement, particularly so in more recent years with the discovery of clinically relevant COMT inhibitors in the late 1980's. While the volume of published research on the COMT enzyme and its inhibitors is substantial, there is no comprehensive, up-to-date source containing all the information available on basic COMT biochemistry and pharmacology, as well as critical review of results from clinical trials. This volume of International Review of Neurobiology summarizes what is currently known about COMT enzyme: its genomics, structure, function and biochemical properties; and presents up-to-date evaluation of the clinical use of COMT inhibitors as an adjunct to levodopa/dopa decarboxylase inhibitor treatment in Parkinson's disease."--Publisher's description
Includes bibliographical references and index
Beschreibung:xii, 323 pages
ISBN:9780123813275
0123813271
9780123813268
0123813263
1282954881
9781282954885

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