Gap junctions: molecular basis of cell communication in health and disease
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego
Academic Press
©2000
|
| Schriftenreihe: | Current topics in membranes
v. 49 |
| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Beschreibung: | Includes bibliographical references and index Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot Marie Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas' disease |
| Beschreibung: | xxvii, 648 pages |
| ISBN: | 9780080585208 0080585205 0121533492 9780121533496 |
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| 650 | 4 | |a Gap Junctions / physiology | |
| 650 | 4 | |a Connexins | |
| 650 | 4 | |a Cell interaction | |
| 650 | 4 | |a Gap junctions (Cell biology) | |
| 650 | 4 | |a Gap junctions (Cell biology) Cell interaction. Connexins | |
| 650 | 4 | |a Jonctions communicantes (Biologie cellulaire) | |
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| dewey-full | 571.6/4 |
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| dewey-ones | 571 - Physiology & related subjects |
| dewey-raw | 571.6/4 |
| dewey-search | 571.6/4 |
| dewey-sort | 3571.6 14 |
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| spelling | Gap junctions molecular basis of cell communication in health and disease edited by Camillo Peracchia San Diego Academic Press ©2000 xxvii, 648 pages txt rdacontent c rdamedia cr rdacarrier Current topics in membranes v. 49 Includes bibliographical references and index Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot Marie Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas' disease Gap Junctions / physiology Connexins Cell interaction Gap junctions (Cell biology) Gap junctions (Cell biology) Cell interaction. Connexins Jonctions communicantes (Biologie cellulaire) Cellules / Interaction SCIENCE / Life Sciences / Cell Biology bisacsh Cell interaction fast Connexins fast Gap junctions (Cell biology) fast Celbiologie gtt Interactie gtt Ziekten gtt Gap junction (DE-588)4197886-9 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Gap junction (DE-588)4197886-9 s 2\p DE-604 Peracchia, Camillo Sonstige oth http://www.sciencedirect.com/science/bookseries/10635823/49 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Gap junctions molecular basis of cell communication in health and disease Gap Junctions / physiology Connexins Cell interaction Gap junctions (Cell biology) Gap junctions (Cell biology) Cell interaction. Connexins Jonctions communicantes (Biologie cellulaire) Cellules / Interaction SCIENCE / Life Sciences / Cell Biology bisacsh Cell interaction fast Connexins fast Gap junctions (Cell biology) fast Celbiologie gtt Interactie gtt Ziekten gtt Gap junction (DE-588)4197886-9 gnd |
| subject_GND | (DE-588)4197886-9 (DE-588)4143413-4 |
| title | Gap junctions molecular basis of cell communication in health and disease |
| title_auth | Gap junctions molecular basis of cell communication in health and disease |
| title_exact_search | Gap junctions molecular basis of cell communication in health and disease |
| title_full | Gap junctions molecular basis of cell communication in health and disease edited by Camillo Peracchia |
| title_fullStr | Gap junctions molecular basis of cell communication in health and disease edited by Camillo Peracchia |
| title_full_unstemmed | Gap junctions molecular basis of cell communication in health and disease edited by Camillo Peracchia |
| title_short | Gap junctions |
| title_sort | gap junctions molecular basis of cell communication in health and disease |
| title_sub | molecular basis of cell communication in health and disease |
| topic | Gap Junctions / physiology Connexins Cell interaction Gap junctions (Cell biology) Gap junctions (Cell biology) Cell interaction. Connexins Jonctions communicantes (Biologie cellulaire) Cellules / Interaction SCIENCE / Life Sciences / Cell Biology bisacsh Cell interaction fast Connexins fast Gap junctions (Cell biology) fast Celbiologie gtt Interactie gtt Ziekten gtt Gap junction (DE-588)4197886-9 gnd |
| topic_facet | Gap Junctions / physiology Connexins Cell interaction Gap junctions (Cell biology) Gap junctions (Cell biology) Cell interaction. Connexins Jonctions communicantes (Biologie cellulaire) Cellules / Interaction SCIENCE / Life Sciences / Cell Biology Celbiologie Interactie Ziekten Gap junction Aufsatzsammlung |
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