Viruses and liver cancer:
Saved in:
| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
Amsterdam
Elsevier
2002
|
| Edition: | 1st ed |
| Series: | Perspectives in medical virology
v. 6 |
| Subjects: | |
| Online Access: | FAW01 URL des Erstveröffentlichers |
| Item Description: | Includes bibliographical references Hepatocellular carcinoma (HCC) is one of the most important complications of chronic viral hepatitis. It usually results in a fatal outcome if not discovered in its earliest stages. Its close association with the hepatitis B and C viruses makes it one of the first human cancers for which there is strong evidence of a viral cause. For this reason it provides a model for studying viral carcinogenesis in humans. In some countries, HCC is one of the most common tumors of adult men. In addition, there is evidence that the incidence of this cancer has doubled in the past 15 to 20 years in many countries, and the incidence has doubled every 20 years for the past half century in Japan. In some studies, the increase has been shown to be due primarily to cases associated with HCV infection. Molecular studies of HCC show that mutations in oncogenes, in various cellular repair pathways, and in tumor suppressor genes together appear to contribute to the development of this cancer. In HCCs associated with hepatitis B virus, the virus itself can interact with tumor suppressor proteins and other cellular signals in ways that probably permit HCC to develop even when there are no mutations in the genes for these signals. This work discusses the latest concepts in molecular biology and the study of HCC which have led to dramatic breakthroughs in our understanding of how it develops |
| Physical Description: | vii, 176 pages |
| ISBN: | 0444505806 9780444505804 |
Staff View
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| 245 | 1 | 0 | |a Viruses and liver cancer |c editor, Edward Tabor |
| 250 | |a 1st ed | ||
| 264 | 1 | |a Amsterdam |b Elsevier |c 2002 | |
| 300 | |a vii, 176 pages | ||
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| 490 | 0 | |a Perspectives in medical virology |v v. 6 | |
| 500 | |a Includes bibliographical references | ||
| 500 | |a Hepatocellular carcinoma (HCC) is one of the most important complications of chronic viral hepatitis. It usually results in a fatal outcome if not discovered in its earliest stages. Its close association with the hepatitis B and C viruses makes it one of the first human cancers for which there is strong evidence of a viral cause. For this reason it provides a model for studying viral carcinogenesis in humans. In some countries, HCC is one of the most common tumors of adult men. In addition, there is evidence that the incidence of this cancer has doubled in the past 15 to 20 years in many countries, and the incidence has doubled every 20 years for the past half century in Japan. In some studies, the increase has been shown to be due primarily to cases associated with HCV infection. Molecular studies of HCC show that mutations in oncogenes, in various cellular repair pathways, and in tumor suppressor genes together appear to contribute to the development of this cancer. In HCCs associated with hepatitis B virus, the virus itself can interact with tumor suppressor proteins and other cellular signals in ways that probably permit HCC to develop even when there are no mutations in the genes for these signals. This work discusses the latest concepts in molecular biology and the study of HCC which have led to dramatic breakthroughs in our understanding of how it develops | ||
| 650 | 4 | |a Liver Neoplasms / etiology | |
| 650 | 4 | |a Hepatitis, Viral, Human / complications | |
| 650 | 4 | |a Viruses | |
| 650 | 4 | |a Virus de l'hépatite | |
| 650 | 4 | |a Foie / Cancer | |
| 650 | 2 | |a Tumeurs du foie / étiologie | |
| 650 | 2 | |a Hépatites virales humaines / complications | |
| 650 | 7 | |a Hepatitis viruses |2 fast | |
| 650 | 7 | |a Liver / Cancer |2 fast | |
| 650 | 7 | |a Foie / Cancer |2 ram | |
| 650 | 7 | |a Virus d'hépatites |2 ram | |
| 650 | 7 | |a Viren |2 swd | |
| 650 | 7 | |a Leberkrebs |2 swd | |
| 650 | 7 | |a Virussjukdomar |2 sao | |
| 650 | 7 | |a Cancer |2 sao | |
| 650 | 4 | |a Liver |x Cancer | |
| 650 | 4 | |a Hepatitis viruses | |
| 650 | 0 | 7 | |a Leberkrebs |0 (DE-588)4034943-3 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Viren |0 (DE-588)4063589-2 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Leberkrebs |0 (DE-588)4034943-3 |D s |
| 689 | 0 | 1 | |a Viren |0 (DE-588)4063589-2 |D s |
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| 700 | 1 | |a Tabor, Edward |e Sonstige |4 oth | |
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Record in the Search Index
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| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99/436 |
| dewey-search | 616.99/436 |
| dewey-sort | 3616.99 3436 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1st ed |
| format | Electronic eBook |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:51:23Z |
| institution | BVB |
| isbn | 0444505806 9780444505804 |
| language | English |
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| physical | vii, 176 pages |
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| series2 | Perspectives in medical virology |
| spelling | Viruses and liver cancer editor, Edward Tabor 1st ed Amsterdam Elsevier 2002 vii, 176 pages txt rdacontent c rdamedia cr rdacarrier Perspectives in medical virology v. 6 Includes bibliographical references Hepatocellular carcinoma (HCC) is one of the most important complications of chronic viral hepatitis. It usually results in a fatal outcome if not discovered in its earliest stages. Its close association with the hepatitis B and C viruses makes it one of the first human cancers for which there is strong evidence of a viral cause. For this reason it provides a model for studying viral carcinogenesis in humans. In some countries, HCC is one of the most common tumors of adult men. In addition, there is evidence that the incidence of this cancer has doubled in the past 15 to 20 years in many countries, and the incidence has doubled every 20 years for the past half century in Japan. In some studies, the increase has been shown to be due primarily to cases associated with HCV infection. Molecular studies of HCC show that mutations in oncogenes, in various cellular repair pathways, and in tumor suppressor genes together appear to contribute to the development of this cancer. In HCCs associated with hepatitis B virus, the virus itself can interact with tumor suppressor proteins and other cellular signals in ways that probably permit HCC to develop even when there are no mutations in the genes for these signals. This work discusses the latest concepts in molecular biology and the study of HCC which have led to dramatic breakthroughs in our understanding of how it develops Liver Neoplasms / etiology Hepatitis, Viral, Human / complications Viruses Virus de l'hépatite Foie / Cancer Tumeurs du foie / étiologie Hépatites virales humaines / complications Hepatitis viruses fast Liver / Cancer fast Foie / Cancer ram Virus d'hépatites ram Viren swd Leberkrebs swd Virussjukdomar sao Cancer sao Liver Cancer Hepatitis viruses Leberkrebs (DE-588)4034943-3 gnd rswk-swf Viren (DE-588)4063589-2 gnd rswk-swf Leberkrebs (DE-588)4034943-3 s Viren (DE-588)4063589-2 s 1\p DE-604 Tabor, Edward Sonstige oth http://www.sciencedirect.com/science/bookseries/01687069/6 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Viruses and liver cancer Liver Neoplasms / etiology Hepatitis, Viral, Human / complications Viruses Virus de l'hépatite Foie / Cancer Tumeurs du foie / étiologie Hépatites virales humaines / complications Hepatitis viruses fast Liver / Cancer fast Foie / Cancer ram Virus d'hépatites ram Viren swd Leberkrebs swd Virussjukdomar sao Cancer sao Liver Cancer Hepatitis viruses Leberkrebs (DE-588)4034943-3 gnd Viren (DE-588)4063589-2 gnd |
| subject_GND | (DE-588)4034943-3 (DE-588)4063589-2 |
| title | Viruses and liver cancer |
| title_auth | Viruses and liver cancer |
| title_exact_search | Viruses and liver cancer |
| title_full | Viruses and liver cancer editor, Edward Tabor |
| title_fullStr | Viruses and liver cancer editor, Edward Tabor |
| title_full_unstemmed | Viruses and liver cancer editor, Edward Tabor |
| title_short | Viruses and liver cancer |
| title_sort | viruses and liver cancer |
| topic | Liver Neoplasms / etiology Hepatitis, Viral, Human / complications Viruses Virus de l'hépatite Foie / Cancer Tumeurs du foie / étiologie Hépatites virales humaines / complications Hepatitis viruses fast Liver / Cancer fast Foie / Cancer ram Virus d'hépatites ram Viren swd Leberkrebs swd Virussjukdomar sao Cancer sao Liver Cancer Hepatitis viruses Leberkrebs (DE-588)4034943-3 gnd Viren (DE-588)4063589-2 gnd |
| topic_facet | Liver Neoplasms / etiology Hepatitis, Viral, Human / complications Viruses Virus de l'hépatite Foie / Cancer Tumeurs du foie / étiologie Hépatites virales humaines / complications Hepatitis viruses Liver / Cancer Virus d'hépatites Viren Leberkrebs Virussjukdomar Cancer Liver Cancer |
| url | http://www.sciencedirect.com/science/bookseries/01687069/6 |
| work_keys_str_mv | AT taboredward virusesandlivercancer |