Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity:
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis Book |
| Language: | English |
| Published: |
[Leipzig]
Max Planck Institute for Human Cognitive and Brain Sciences
2016
|
| Series: | MPI series in human cognitive and brain sciences
179 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 97 Seiten, 34 verschieden gezählte Seiten Illustrationen, Diagramme (farbig) |
| ISBN: | 9783941504653 |
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| 245 | 1 | 0 | |a Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity |c von M.Sc., Smadar A., Ovadia-Caro, Geburtsname: Ovadia |
| 264 | 1 | |a [Leipzig] |b Max Planck Institute for Human Cognitive and Brain Sciences |c 2016 | |
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| 502 | |b Dissertation |c Humboldt-Universität zu Berlin |d 2016 | ||
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Record in the Search Index
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|---|---|
| adam_text | TABLE
OF
CONTENTS
SUMMARY
13
ZUSAMMENFASSUNG
15
LIST
OF
ORIGINAL
RESEARCH
ARTICLES
17
LIST
OF
ABBREVIATIONS
18
LIST
OF
FIGURES
19
1
INTRODUCTION
20
2
THEORETICAL
BACKGROUND
23
2.1
G
ENERAL
OVERVIEW
OF
STROKE
......................................................................................
23
2.2
T
HEORIES
OF
PLASTICITY
FOLLOWING
STROKE
.................................................................
24
2.2.1
UNDERSTANDING
STROKE:
FROM
LOCALIZATION
TO
NETWORK
DISRUPTION
.......................
24
2.2.2
DIASCHISIS:
CONNECTIVITY
AS
A
MEDIATING
MECHANISM
FOR
NETWORK
DISRUPTION
AND
REORGANIZATION
.............................................................................................................
25
2.3
E
MPIRICAL
EVIDENCE
FOR
DIASCHISIS
AND
NETWORK
DISRUPTION
....................................
26
2.3.1
PLASTICITY
AT
THE
CELLULAR
LEVEL
FOLLOWING
STROKE
....................................................
26
2.3.2
FMRI
STUDIES
OF
PLASTICITY
FOLLOWING
STROKE
..........................................................
27
2.3.3
RS-FMRL
STUDIES
OF
PLASTICITY
FOLLOWING
STROKE
......................................................
28
2.3.4
FROM
SINGLE
NETWORK
TO
MULTIPLE
NETWORKS
-
THE
CHALLENGE
OF
HETEROGENEITY
... 29
3
RESEARCH
QUESTIONS
AND
HYPOTHESES
31
4
GENERAL
METHODOLOGICAL
APPROACH
34
4.1
T
HE
RESTLESS
BRAIN:
INTRINSIC
BRAIN
ACTIVITY
.............................................................
34
4.2
R
ESTING
-
STATE
F
MRI:
MEASURING
INTRINSIC
ACTIVITY
USING
THE
BOLD
SIGNAL
.............
35
4.3
A
NALYSIS
OF
FUNCTIONAL
CONNECTIVITY
:
METHODOLOGICAL
TOOLS
.................................
37
4.4
RS
-
F
MRI
AS
A
CLINICAL
TOOL
TO
STUDY
PATHOLOGIES
AND
PLASTICITY
.............................
39
5
SUMMARY
OF
RELATED
PAPERS
41
5.1
S
TUDY
I:
C
ONNECTIVITY
CONCORDANCE
MAPPING
:
A
NEW
TOOL
FOR
MODEL
-
FREE
ANALYSIS
OF
F
MRI
DATA
OF
THE
HUMAN
BRAIN
(L
OHMANN
,
ET
AL
.,
2012)
................................................
41
5.1.1
BACKGROUND
..........................................................................................................
41
5.1.2
METHODS
................................................................................................................
42
5.1.3
RESULTS
..................................................................................................................
44
5.1.4
DISCUSSION
.............................................................................................................
46
5.2
S
TUDY
II:
L
ONGITUDINAL
EFFECTS
OF
LESIONS
ON
FUNCTIONAL
NETWORKS
AFTER
STROKE
(O
VADIA
-C
ARO
,
ET
AL
.,
2013)
.............................................................................................48
5.2.1
BACKGROUND
.........................................................................................................
48
5.2.2
METHODS
................................................................................................................
49
5.2.4
DISCUSSION
.............................................................................................................
53
10
5.3
S
TUDY
III:
T
HE
VALUE
OF
RESTING
-
STATE
FUNCTIONAL
MAGNETIC
RESONANCE
IMAGING
IN
STROKE
(OVADIA-CARO,
ET
AL.,
2014)
................................................................................
55
5.3.1
BACKGROUND
.........................................................................................................
55
5.3.2
USING
RS-FMRI
IN
THE
ACUTE
PHASE
AS
A
MEASURE
OF
LOCAL
PERFUSION
.....................
55
5.3.3
USING
RS-FMRI
IN
THE
SUB-ACUTE
AND
CHRONIC
PHASE
TO
STUDY
REORGANIZATION
.....
56
5.3.4
LIMITATIONS
AND
CONSIDERATIONS
...........................................................................
58
5.3.5
CONCLUSIONS
..........................................................................................................
59
6
GENERAL
DISCUSSION
60
6.1
SUMMARY
OF
RESULTS
..................................................................................................
60
6.2
PRACTICAL
AND
THEORETICAL
IMPLICATIONS
..................................................................
62
6.3
C
ONSIDERATIONS
AND
SUGGESTIONS
FOR
FURTHER
RESEARCH
..........................................
64
6.4
C
ONCLUSIONS
..............................................................................................................
67
REFERENCES
69
7
SUPPLEMENTS
93
7.1
CURRICULUM
VITAE
......................................................................................................
93
7.2
PUBLICATION
LIST
.........................................................................................................
96
7.3
RESEARCH
ARTICLES
......................................................................................................
97
11
|
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| author | Ovadia-Caro, Smadar 1979- |
| author_GND | (DE-588)1124188509 |
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| author_variant | s o c soc |
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| bvnumber | BV044266951 |
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| dewey-full | 610 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 610 - Medicine and health |
| dewey-raw | 610 |
| dewey-search | 610 |
| dewey-sort | 3610 |
| dewey-tens | 610 - Medicine and health |
| discipline | Psychologie Medizin |
| format | Thesis Book |
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| indexdate | 2024-07-10T07:48:14Z |
| institution | BVB |
| isbn | 9783941504653 |
| language | English |
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| physical | 97 Seiten, 34 verschieden gezählte Seiten Illustrationen, Diagramme (farbig) |
| publishDate | 2016 |
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| publisher | Max Planck Institute for Human Cognitive and Brain Sciences |
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| spelling | Ovadia-Caro, Smadar 1979- Verfasser (DE-588)1124188509 aut Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity von M.Sc., Smadar A., Ovadia-Caro, Geburtsname: Ovadia [Leipzig] Max Planck Institute for Human Cognitive and Brain Sciences 2016 97 Seiten, 34 verschieden gezählte Seiten Illustrationen, Diagramme (farbig) txt rdacontent n rdamedia nc rdacarrier MPI series in human cognitive and brain sciences 179 Dissertation Humboldt-Universität zu Berlin 2016 Nervennetz (DE-588)4041638-0 gnd rswk-swf Schlaganfall (DE-588)4052588-0 gnd rswk-swf Gehirn (DE-588)4019752-9 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Schlaganfall (DE-588)4052588-0 s Gehirn (DE-588)4019752-9 s Nervennetz (DE-588)4041638-0 s DE-604 MPI series in human cognitive and brain sciences 179 (DE-604)BV019666410 179 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029671692&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ovadia-Caro, Smadar 1979- Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity MPI series in human cognitive and brain sciences Nervennetz (DE-588)4041638-0 gnd Schlaganfall (DE-588)4052588-0 gnd Gehirn (DE-588)4019752-9 gnd |
| subject_GND | (DE-588)4041638-0 (DE-588)4052588-0 (DE-588)4019752-9 (DE-588)4113937-9 |
| title | Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity |
| title_auth | Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity |
| title_exact_search | Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity |
| title_full | Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity von M.Sc., Smadar A., Ovadia-Caro, Geburtsname: Ovadia |
| title_fullStr | Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity von M.Sc., Smadar A., Ovadia-Caro, Geburtsname: Ovadia |
| title_full_unstemmed | Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity von M.Sc., Smadar A., Ovadia-Caro, Geburtsname: Ovadia |
| title_short | Plasticity following stroke: the recovery of functional networks as measured by resting-state functional connectivity |
| title_sort | plasticity following stroke the recovery of functional networks as measured by resting state functional connectivity |
| topic | Nervennetz (DE-588)4041638-0 gnd Schlaganfall (DE-588)4052588-0 gnd Gehirn (DE-588)4019752-9 gnd |
| topic_facet | Nervennetz Schlaganfall Gehirn Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029671692&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV019666410 |
| work_keys_str_mv | AT ovadiacarosmadar plasticityfollowingstroketherecoveryoffunctionalnetworksasmeasuredbyrestingstatefunctionalconnectivity |