Optical & acoustical microfluidic actuation elements: building blocks for use in sensing actuating lab-on-chip systems
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| Main Author: | |
|---|---|
| Format: | Thesis Book |
| Language: | English |
| Published: |
München
Verlag Dr. Hut
2016
|
| Edition: | 1. Auflage |
| Subjects: | |
| Online Access: | http://www.dr.hut-verlag.de/978-3-8439-2890-8.html Inhaltstext Inhaltsverzeichnis |
| Physical Description: | XVIII, 132 Seiten Illustrationen, Diagramme |
| ISBN: | 9783843928908 3843928908 |
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Record in the Search Index
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CONTENTS
I INTRODUCTION 1
1 INTRODUCTION 3
1 1 Why Miniaturization? 3
1 2 Actuation in Microfluidic Devices 4
1 3 Why this thesis? 5
1 4 Outline of this thesis 6
2 basics 9
2 1 Microfluidics 9
211 Fluid Dynamics 9
212 Mixing 11
213 Surface Tension amp; Contact Angles 12
214 Droplet Creation 13
2 2 Acoustics 14
221 Piezoelectricity 14
222 Ultrasonics 15
223 Ultrasonic Streaming 15
224 Acoustophoresis 17
2 3 Optics 18
231 Ray Optics 18
232 Wave Optics 22
II TECHNOLOGY 25
3 EXTERNAL ULTRASONIC AT IO N SYSTEM 27
3 1 Piezoelectric transducer 27
3 2 Driver for ultrasonics 29
321 Anti-Shoot-Through 31
322 H-Bridge 32
3 3 Ultrasonic horn coupling 33
331 Horn design 34
332 Coupling from horn to chip 35
3 4 Conclusion 36
4 DEVICE FABRICATION 41
XIII
XIV
CONTENTS
4 1 Rapid Prototyping 41
411 Stereo-lithographic Printing 41
412 Grafting of Stereo-lithographic Parts 43
4 2 Sampling 48
421 Capillary Introduction of Liquids 48
422 Conclusion 53
4 3 Classical Cleanroom Fabrication 54
431 Optofluidic PDMS Molding 54
III APPLICATIONS IN SENSOR-SYSTEMS 57
5 SENSING 59
5 1 ELISA 62
5 2 Conclusion 65
6 ON-CHIP SAMPLE PREPARATION 67
6 1 Sample filtration through Acoustophoresis 69
611 Sample preparation chip 69
612 Separation experiment of artificial blood
sample 71
6 2 Conclusion 71
7 SUPPORT ACTUATORS 73
7 1 Microfluidic Chip amp; Setup 74
7 2 Mixing through ultrasonic streaming 75
721 Working Principle amp; Experimental Setup 76
722 Results 77
7 3 Dispersion of Particles via Ultrasound 79
731 Working Principle amp; Experimental Setup 80
732 Results 81
7 4 Ultrasonic cleaning of non-specifically bound
protein 82
741 Working Principle amp; Experimental Setup 83
742 Results 84
7 5 Conclusion 85
IV APPLICATIONS IN ACTUATOR-SYSTEMS 87
8 OPTOFLUIDIC DROPLET MULTIPLEXING SYSTEM 89
8 1 Theoretical Analysis 91
811 Optics 91
812 Fluid-mechanics 94
CONTENTS I XV
813 Loss analysis 98
8 2 Optofluidical Actuation Through Movement 98
821 Design 98
822 Liquids 99
8 3 Setup amp; Experiment 100
831 Experiments 100
8 4 Results amp; Discussion 101
9 OPTOFLUIDIC OUT-OF-PLANE DELAY-LINE 105
9 1 Theoretical Analysis 106
911 Optics 106
912 Fluid-mechanics 108
9 2 Optofluidical Actuation Through Mixing 109
921 Out-of-Plane Design 109
922 Chip-Design and Fabrication 111
9 3 Setup amp; Experiment 112
9 4 Results amp; Discussion 113
V CONCLUSION if OUTLOOK 115
10 CONCLUSION 117 |
| any_adam_object | 1 |
| author | Brandhoff, Lukas |
| author_GND | (DE-588)1121326013 |
| author_facet | Brandhoff, Lukas |
| author_role | aut |
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| bvnumber | BV043993603 |
| classification_rvk | ZN 3750 ZQ 5460 |
| ctrlnum | (OCoLC)975034703 (DE-599)DNB112152429X |
| dewey-full | 621.3 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 621 - Applied physics |
| dewey-raw | 621.3 |
| dewey-search | 621.3 |
| dewey-sort | 3621.3 |
| dewey-tens | 620 - Engineering and allied operations |
| discipline | Elektrotechnik / Elektronik / Nachrichtentechnik Mess-/Steuerungs-/Regelungs-/Automatisierungstechnik / Mechatronik |
| edition | 1. Auflage |
| format | Thesis Book |
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| id | DE-604.BV043993603 |
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| indexdate | 2024-08-03T03:14:14Z |
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| language | English |
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| physical | XVIII, 132 Seiten Illustrationen, Diagramme |
| publishDate | 2016 |
| publishDateSearch | 2016 |
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| publisher | Verlag Dr. Hut |
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| spelling | Brandhoff, Lukas Verfasser (DE-588)1121326013 aut Optical & acoustical microfluidic actuation elements building blocks for use in sensing actuating lab-on-chip systems Lukas Brandhoff 1. Auflage München Verlag Dr. Hut 2016 XVIII, 132 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Dissertation Universität Bremen 2016 Mikrofluidik (DE-588)4803438-1 gnd rswk-swf Lab on a Chip (DE-588)7610677-9 gnd rswk-swf Aktor (DE-588)4198914-4 gnd rswk-swf Acoustics Microfluidic Actuation Elements Microfluids (DE-588)4113937-9 Hochschulschrift gnd-content Mikrofluidik (DE-588)4803438-1 s Aktor (DE-588)4198914-4 s Lab on a Chip (DE-588)7610677-9 s DE-604 Verlag Dr. Hut (München) (DE-588)10174118-2 pbl http://www.dr.hut-verlag.de/978-3-8439-2890-8.html Verlag X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=85ec3967d3d54fd395b084b0fba6e771&prov=M&dok_var=1&dok_ext=htm Inhaltstext HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029401753&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Brandhoff, Lukas Optical & acoustical microfluidic actuation elements building blocks for use in sensing actuating lab-on-chip systems Mikrofluidik (DE-588)4803438-1 gnd Lab on a Chip (DE-588)7610677-9 gnd Aktor (DE-588)4198914-4 gnd |
| subject_GND | (DE-588)4803438-1 (DE-588)7610677-9 (DE-588)4198914-4 (DE-588)4113937-9 |
| title | Optical & acoustical microfluidic actuation elements building blocks for use in sensing actuating lab-on-chip systems |
| title_auth | Optical & acoustical microfluidic actuation elements building blocks for use in sensing actuating lab-on-chip systems |
| title_exact_search | Optical & acoustical microfluidic actuation elements building blocks for use in sensing actuating lab-on-chip systems |
| title_full | Optical & acoustical microfluidic actuation elements building blocks for use in sensing actuating lab-on-chip systems Lukas Brandhoff |
| title_fullStr | Optical & acoustical microfluidic actuation elements building blocks for use in sensing actuating lab-on-chip systems Lukas Brandhoff |
| title_full_unstemmed | Optical & acoustical microfluidic actuation elements building blocks for use in sensing actuating lab-on-chip systems Lukas Brandhoff |
| title_short | Optical & acoustical microfluidic actuation elements |
| title_sort | optical acoustical microfluidic actuation elements building blocks for use in sensing actuating lab on chip systems |
| title_sub | building blocks for use in sensing actuating lab-on-chip systems |
| topic | Mikrofluidik (DE-588)4803438-1 gnd Lab on a Chip (DE-588)7610677-9 gnd Aktor (DE-588)4198914-4 gnd |
| topic_facet | Mikrofluidik Lab on a Chip Aktor Hochschulschrift |
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