Network medicine: complex systems in human disease and therapeutics
"Network medicine, a new field which developed from the application of systems biology approaches to human disease, embraces the complexity of multifactorial influences on disease, which can be driven by non-linear effects and molecular and statistical interactions.The development of comprehens...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, Massachusetts
Harvard University Press
2017
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Zusammenfassung: | "Network medicine, a new field which developed from the application of systems biology approaches to human disease, embraces the complexity of multifactorial influences on disease, which can be driven by non-linear effects and molecular and statistical interactions.The development of comprehensive and affordable Omics platforms provides the data types for network medicine, and graph theory and statistical physics provide the theoretical framework to analyze networks. While network medicine provides a fundamentally different approach to understanding disease etiology, it will also lead to key differences in how diseases are treated...with multiple molecular targets that may require manipulation in a coordinated, dynamic fashion. Much remains to be learned regarding the optimal approaches to integrate different Omics data types and to perform network analyses; this book provides an overview of the progress that has been made and the challenges that remain."... |
| Beschreibung: | Includes index |
| Beschreibung: | xi, 436 Seiten Illustrationen |
| ISBN: | 9780674436534 |
Internformat
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Datensatz im Suchindex
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|---|---|
| adam_text | NETWORK MEDICINE
/
: 2016
TABLE OF CONTENTS / INHALTSVERZEICHNIS
SCIENTIFIC BASIS OF NETWORK MEDICINE / EDWIN K. SILVERMAN AND JOSEPH
LOSCALZO
INTRODUCTION TO NETWORK ANALYSIS / JORG MENCHE AND ALBERT-LASZLO
BARABASI
HUMAN INTERACTOMES IN NETWORK MEDICINE / MICHAEL E. CUSICK, BENOIT
CHARLOTEAUX, THOMAS ROLLAND, MICHAEL A. CALDERWOOD, DAVID E. HILL, AND
MARC VIDAL
SOCIAL NETWORKS IN HUMAN DISEASE / MARTIN W. SCHOEN AND DOUGLAS LUKE
PHENOTYPE, PATHOPHENOTYPE AND ENDO(PATHO)PHENOTYPE IN NETWORK MEDICINE /
CALUM A. MACRAE
A NEW PARADIGM FOR DEFINING HUMAN DISEASE AND THERAPY / JOSEPH LOSCALZO
COMPLEX DISEASE GENETICS AND NETWORK MEDICINE / EDWIN K. SILVERMAN
TRANSCRIPTOMICS AND NETWORK MEDICINE / KIMBERLY GLASS AND JOHN
QUACKENBUSH
POST-TRANSLATIONAL MODIFICATIONS OF THE PROTEOME: THE EXAMPLE OF TAU IN
THE NEURON AND THE BRAIN / GUY LIPPENS, JEREMY GUNAWARDENA, ISABELLE
LANDRIEU, CAROLINE SMET-NOCCA, SUDHAKARAN PRABAKARAN, BENJAMIN PARENT,
ARNAUD LEROY, AND I. HUVENT
EPIGENETICS AND NETWORK MEDICINE / DAWN L. DEMEO AND SCOTT T. WEISS
METABOLOMICS AND NETWORK MEDICINE / JESSICA LASKY-SU AND CLARY B. CLISH
USING INTEGRATIVE OMICS APPROACHES IN NETWORK MEDICINE / SHUYI MA, JOHN
C. EARLS, JAMES A. EDDY, AND NATHAN D. PRICE
CANCER NETWORK MEDICINE / TAKESHI HASE, SAMIK GHOSH, SUCHEENDRA K
PALANIAPPAN, AND HIROAKI KITANO
SYSTEMS PHARMACOLOGY IN NETWORK MEDICINE / EDWIN K. SILVERMAN AND JOSEPH
LOSCALZO
SYSTEMS APPROACHES TO CLINICAL TRIALS / ELLIOTT M. ANTMAN
MICROBIOMICS IN NETWORK MEDICINE / JOANNE E. SORDILLO, GEORGE M.
WEINSTOCK, AND AUGUSTO A. LITONJUA
DIESES SCHRIFTSTCK WURDE MASCHINELL ERZEUGT.
|
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| spelling | Network medicine complex systems in human disease and therapeutics edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman Cambridge, Massachusetts Harvard University Press 2017 xi, 436 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Includes index "Network medicine, a new field which developed from the application of systems biology approaches to human disease, embraces the complexity of multifactorial influences on disease, which can be driven by non-linear effects and molecular and statistical interactions.The development of comprehensive and affordable Omics platforms provides the data types for network medicine, and graph theory and statistical physics provide the theoretical framework to analyze networks. While network medicine provides a fundamentally different approach to understanding disease etiology, it will also lead to key differences in how diseases are treated...with multiple molecular targets that may require manipulation in a coordinated, dynamic fashion. Much remains to be learned regarding the optimal approaches to integrate different Omics data types and to perform network analyses; this book provides an overview of the progress that has been made and the challenges that remain."... Datenverarbeitung Medical informatics Data integration (Computer science) Diseases Causes and theories of causation Data processing Therapeutics Data processing Medizinische Informatik (DE-588)4038261-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Medizinische Informatik (DE-588)4038261-8 s DE-604 Loscalzo, Joseph 1951- (DE-588)141560894 edt Barabási, Albert-László 1967- (DE-588)17283855X edt Silverman, Edwin K. edt LoC Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029388975&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Network medicine complex systems in human disease and therapeutics Datenverarbeitung Medical informatics Data integration (Computer science) Diseases Causes and theories of causation Data processing Therapeutics Data processing Medizinische Informatik (DE-588)4038261-8 gnd |
| subject_GND | (DE-588)4038261-8 (DE-588)4143413-4 |
| title | Network medicine complex systems in human disease and therapeutics |
| title_auth | Network medicine complex systems in human disease and therapeutics |
| title_exact_search | Network medicine complex systems in human disease and therapeutics |
| title_full | Network medicine complex systems in human disease and therapeutics edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman |
| title_fullStr | Network medicine complex systems in human disease and therapeutics edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman |
| title_full_unstemmed | Network medicine complex systems in human disease and therapeutics edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman |
| title_short | Network medicine |
| title_sort | network medicine complex systems in human disease and therapeutics |
| title_sub | complex systems in human disease and therapeutics |
| topic | Datenverarbeitung Medical informatics Data integration (Computer science) Diseases Causes and theories of causation Data processing Therapeutics Data processing Medizinische Informatik (DE-588)4038261-8 gnd |
| topic_facet | Datenverarbeitung Medical informatics Data integration (Computer science) Diseases Causes and theories of causation Data processing Therapeutics Data processing Medizinische Informatik Aufsatzsammlung |
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