This book provides the first systematic treatment of the thermodynamic theory of site-specific effects in biological macromolecules. It describes the phenomenological and conceptual bases required to allow a mechanistic understanding of these effects from analysis of experimental data. The thermodyn...

Full description

Bibliographic Details

Main Author:	Di Cera, Enrico (Author)
Format:	Electronic eBook
Language:	English
Published:	Cambridge Cambridge University Press 1995
Subjects:	Binding sites (Biochemistry) / Thermodynamics Ligand binding (Biochemistry) / Thermodynamics Cooperative binding (Biochemistry) / Thermodynamics Macromolecules / Thermodynamics Thermodynamik Chemische Bindung Makromolekül
Online Access:	BSB01 FHN01 Volltext
Summary:	This book provides the first systematic treatment of the thermodynamic theory of site-specific effects in biological macromolecules. It describes the phenomenological and conceptual bases required to allow a mechanistic understanding of these effects from analysis of experimental data. The thermodynamic theory also results in novel experimental strategies that enable the derivation of information on local, site-specific properties of a macromolecular system from analysis of perturbed global properties. The treatment focuses on binding phenomena, but is amenable to extension both conceptually and formally to the analysis of other cooperative processes, such as folding and helix–coil transitions. This book will interest any scientist involved in structure–function studies of biological macromolecules, or as a text for graduate students in biochemistry and biophysics
Item Description:	Title from publisher's bibliographic system (viewed on 05 Oct 2015)
Physical Description:	1 online resource (xvi, 296 pages)
ISBN:	9780511524837
DOI:	10.1017/CBO9780511524837