Brain drug targeting: the future of brain drug development
The thesis of this innovative and challenging book, first published in 2001, is that brain drug development has been restricted by the failure of adequate brain drug targeting, and that this is an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromol...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Cambridge University Press
2001
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| Schlagworte: | |
| Online-Zugang: | BSB01 FHN01 Volltext |
| Zusammenfassung: | The thesis of this innovative and challenging book, first published in 2001, is that brain drug development has been restricted by the failure of adequate brain drug targeting, and that this is an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromolecules. The author, a world leader in the study of the blood-brain barrier and its clinical implications, reviews the field of neurotherapeutics from the point of view of drug targeting. He surveys the scientific and clinical basis of drug delivery across biological membranes, including topics such as genetically engineered trojan horses for drug targeting, antisense neurotherapeutics, and gene therapy of brain disorders. At a time when there are few significant new drug treatments in prospect for common neurological diseases, this authoritative review will encourage a wide range of clinicians and neuroscientists to reexamine the development and use of drugs in treating disorders of the central nervous system |
| Beschreibung: | Title from publisher's bibliographic system (viewed on 05 Oct 2015) |
| Beschreibung: | 1 online resource (xvii, 353 pages) |
| ISBN: | 9780511549571 |
| DOI: | 10.1017/CBO9780511549571 |
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| 520 | |a The thesis of this innovative and challenging book, first published in 2001, is that brain drug development has been restricted by the failure of adequate brain drug targeting, and that this is an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromolecules. The author, a world leader in the study of the blood-brain barrier and its clinical implications, reviews the field of neurotherapeutics from the point of view of drug targeting. He surveys the scientific and clinical basis of drug delivery across biological membranes, including topics such as genetically engineered trojan horses for drug targeting, antisense neurotherapeutics, and gene therapy of brain disorders. At a time when there are few significant new drug treatments in prospect for common neurological diseases, this authoritative review will encourage a wide range of clinicians and neuroscientists to reexamine the development and use of drugs in treating disorders of the central nervous system | ||
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Datensatz im Suchindex
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| author | Pardridge, William M. |
| author_facet | Pardridge, William M. |
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| dewey-full | 615/.78 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.78 |
| dewey-search | 615/.78 |
| dewey-sort | 3615 278 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1017/CBO9780511549571 |
| format | Electronic eBook |
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| indexdate | 2024-07-10T07:39:20Z |
| institution | BVB |
| isbn | 9780511549571 |
| language | English |
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| spelling | Pardridge, William M. Verfasser aut Brain drug targeting the future of brain drug development William M. Pardridge Cambridge Cambridge University Press 2001 1 online resource (xvii, 353 pages) txt rdacontent c rdamedia cr rdacarrier Title from publisher's bibliographic system (viewed on 05 Oct 2015) The thesis of this innovative and challenging book, first published in 2001, is that brain drug development has been restricted by the failure of adequate brain drug targeting, and that this is an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromolecules. The author, a world leader in the study of the blood-brain barrier and its clinical implications, reviews the field of neurotherapeutics from the point of view of drug targeting. He surveys the scientific and clinical basis of drug delivery across biological membranes, including topics such as genetically engineered trojan horses for drug targeting, antisense neurotherapeutics, and gene therapy of brain disorders. At a time when there are few significant new drug treatments in prospect for common neurological diseases, this authoritative review will encourage a wide range of clinicians and neuroscientists to reexamine the development and use of drugs in treating disorders of the central nervous system Neuropharmacology Drug targeting Brain / Effect of drugs on Blood-brain barrier Targeted drug delivery (DE-588)4302415-4 gnd rswk-swf Gehirn (DE-588)4019752-9 gnd rswk-swf Gehirn (DE-588)4019752-9 s Targeted drug delivery (DE-588)4302415-4 s 1\p DE-604 Erscheint auch als Druckausgabe 978-0-521-15446-8 Erscheint auch als Druckausgabe 978-0-521-80077-8 https://doi.org/10.1017/CBO9780511549571 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Pardridge, William M. Brain drug targeting the future of brain drug development Neuropharmacology Drug targeting Brain / Effect of drugs on Blood-brain barrier Targeted drug delivery (DE-588)4302415-4 gnd Gehirn (DE-588)4019752-9 gnd |
| subject_GND | (DE-588)4302415-4 (DE-588)4019752-9 |
| title | Brain drug targeting the future of brain drug development |
| title_auth | Brain drug targeting the future of brain drug development |
| title_exact_search | Brain drug targeting the future of brain drug development |
| title_full | Brain drug targeting the future of brain drug development William M. Pardridge |
| title_fullStr | Brain drug targeting the future of brain drug development William M. Pardridge |
| title_full_unstemmed | Brain drug targeting the future of brain drug development William M. Pardridge |
| title_short | Brain drug targeting |
| title_sort | brain drug targeting the future of brain drug development |
| title_sub | the future of brain drug development |
| topic | Neuropharmacology Drug targeting Brain / Effect of drugs on Blood-brain barrier Targeted drug delivery (DE-588)4302415-4 gnd Gehirn (DE-588)4019752-9 gnd |
| topic_facet | Neuropharmacology Drug targeting Brain / Effect of drugs on Blood-brain barrier Targeted drug delivery Gehirn |
| url | https://doi.org/10.1017/CBO9780511549571 |
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