Imaginal discs: the genetic and cellular logic of pattern formation
Many of the 14,000 genes of Drosophila are involved in the development of imaginal discs. These hollow sacs of cells make adult structures during metamorphosis, and their study is crucial to comprehending how a larva becomes a fully-functioning fly. This book examines the genetic circuitry of the we...
Saved in:
| Main Author: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Cambridge
Cambridge University Press
2002
|
| Series: | Developmental and cell biology series
39 |
| Subjects: | |
| Online Access: | BSB01 FHN01 Volltext |
| Summary: | Many of the 14,000 genes of Drosophila are involved in the development of imaginal discs. These hollow sacs of cells make adult structures during metamorphosis, and their study is crucial to comprehending how a larva becomes a fully-functioning fly. This book examines the genetic circuitry of the well-known 'fruit fly', tackling questions of cell assemblage and pattern formation, of the hows and the whys behind the development of the fly. After an initial examination of the proximity versus pedigree imperatives, the book delves into bristle pattern formation and disc development, with entire chapters devoted to the leg, wing, and eye. Extensive appendices include a glossary of protein domains, catalogues of well-studied genes, and an outline of signaling pathways. More than 30 wiring diagrams among over 60 detailed schematics clarify the text. No student or practising scientist engaged in the study of Drosophila genetics should be without this comprehensive reference |
| Item Description: | Title from publisher's bibliographic system (viewed on 05 Oct 2015) |
| Physical Description: | 1 online resource (xv, 460 pages) |
| ISBN: | 9780511529733 |
| DOI: | 10.1017/CBO9780511529733 |
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| 505 | 8 | 0 | |g Ch. 1 |t Cell Lineage vs. Intercellular Signaling |t Discs are not clones |t No part of a disc is a clone, except claws and tiny sense organs |t Cells belong to lineage "compartments" |g Ch. 2 |t The Bristle |t Numb segregates asymmetrically and dictates bristle cell fates |t Delta needs to activate Notch, but not as a signal per se |t Amnesic cells can use sequential gating to simulate a binary code |t Notch must go to the nucleus to function |t E(spl)-C genes are Su(H) targets but play no role in the SOP lineage |t The transcription factor Tramtrack implements some cell identities |t Hairless titrated Su(H) |t Several other genes help determine the 5 cell fates |t Pox neuro and Cut specify bristle type |t Bract cells are induced by bristle cells |
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Record in the Search Index
| _version_ | 1804176884429225984 |
|---|---|
| any_adam_object | |
| author | Held, Lewis I. 1951- |
| author_facet | Held, Lewis I. 1951- |
| author_role | aut |
| author_sort | Held, Lewis I. 1951- |
| author_variant | l i h li lih |
| building | Verbundindex |
| bvnumber | BV043942030 |
| classification_rvk | WG 5900 WX 6400 |
| collection | ZDB-20-CBO |
| contents | Cell Lineage vs. Intercellular Signaling Discs are not clones No part of a disc is a clone, except claws and tiny sense organs Cells belong to lineage "compartments" The Bristle Numb segregates asymmetrically and dictates bristle cell fates Delta needs to activate Notch, but not as a signal per se Amnesic cells can use sequential gating to simulate a binary code Notch must go to the nucleus to function E(spl)-C genes are Su(H) targets but play no role in the SOP lineage The transcription factor Tramtrack implements some cell identities Hairless titrated Su(H) Several other genes help determine the 5 cell fates Pox neuro and Cut specify bristle type Bract cells are induced by bristle cells |
| ctrlnum | (ZDB-20-CBO)CR9780511529733 (OCoLC)849886948 (DE-599)BVBBV043942030 |
| dewey-full | 576.5 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 576 - Genetics and evolution |
| dewey-raw | 576.5 |
| dewey-search | 576.5 |
| dewey-sort | 3576.5 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| doi_str_mv | 10.1017/CBO9780511529733 |
| format | Electronic eBook |
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| id | DE-604.BV043942030 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:39:16Z |
| institution | BVB |
| isbn | 9780511529733 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029351000 |
| oclc_num | 849886948 |
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| physical | 1 online resource (xv, 460 pages) |
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| publishDate | 2002 |
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| publisher | Cambridge University Press |
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| series2 | Developmental and cell biology series |
| spelling | Held, Lewis I. 1951- Verfasser aut Imaginal discs the genetic and cellular logic of pattern formation Lewis I. Held, Jr Cambridge Cambridge University Press 2002 1 online resource (xv, 460 pages) txt rdacontent c rdamedia cr rdacarrier Developmental and cell biology series 39 Title from publisher's bibliographic system (viewed on 05 Oct 2015) Ch. 1 Cell Lineage vs. Intercellular Signaling Discs are not clones No part of a disc is a clone, except claws and tiny sense organs Cells belong to lineage "compartments" Ch. 2 The Bristle Numb segregates asymmetrically and dictates bristle cell fates Delta needs to activate Notch, but not as a signal per se Amnesic cells can use sequential gating to simulate a binary code Notch must go to the nucleus to function E(spl)-C genes are Su(H) targets but play no role in the SOP lineage The transcription factor Tramtrack implements some cell identities Hairless titrated Su(H) Several other genes help determine the 5 cell fates Pox neuro and Cut specify bristle type Bract cells are induced by bristle cells Many of the 14,000 genes of Drosophila are involved in the development of imaginal discs. These hollow sacs of cells make adult structures during metamorphosis, and their study is crucial to comprehending how a larva becomes a fully-functioning fly. This book examines the genetic circuitry of the well-known 'fruit fly', tackling questions of cell assemblage and pattern formation, of the hows and the whys behind the development of the fly. After an initial examination of the proximity versus pedigree imperatives, the book delves into bristle pattern formation and disc development, with entire chapters devoted to the leg, wing, and eye. Extensive appendices include a glossary of protein domains, catalogues of well-studied genes, and an outline of signaling pathways. More than 30 wiring diagrams among over 60 detailed schematics clarify the text. No student or practising scientist engaged in the study of Drosophila genetics should be without this comprehensive reference Drosophila melanogaster / Genetics Drosophila melanogaster / Embryology Drosophila melanogaster / Morphogenesis / Molecular aspects Cellular signal transduction Cell interaction Taufliege (DE-588)4078168-9 gnd rswk-swf Embryologie (DE-588)4014562-1 gnd rswk-swf Genetik (DE-588)4071711-2 gnd rswk-swf Taufliege (DE-588)4078168-9 s Genetik (DE-588)4071711-2 s 1\p DE-604 Embryologie (DE-588)4014562-1 s 2\p DE-604 Erscheint auch als Druckausgabe 978-0-521-01835-7 Erscheint auch als Druckausgabe 978-0-521-58445-6 https://doi.org/10.1017/CBO9780511529733 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Held, Lewis I. 1951- Imaginal discs the genetic and cellular logic of pattern formation Cell Lineage vs. Intercellular Signaling Discs are not clones No part of a disc is a clone, except claws and tiny sense organs Cells belong to lineage "compartments" The Bristle Numb segregates asymmetrically and dictates bristle cell fates Delta needs to activate Notch, but not as a signal per se Amnesic cells can use sequential gating to simulate a binary code Notch must go to the nucleus to function E(spl)-C genes are Su(H) targets but play no role in the SOP lineage The transcription factor Tramtrack implements some cell identities Hairless titrated Su(H) Several other genes help determine the 5 cell fates Pox neuro and Cut specify bristle type Bract cells are induced by bristle cells Drosophila melanogaster / Genetics Drosophila melanogaster / Embryology Drosophila melanogaster / Morphogenesis / Molecular aspects Cellular signal transduction Cell interaction Taufliege (DE-588)4078168-9 gnd Embryologie (DE-588)4014562-1 gnd Genetik (DE-588)4071711-2 gnd |
| subject_GND | (DE-588)4078168-9 (DE-588)4014562-1 (DE-588)4071711-2 |
| title | Imaginal discs the genetic and cellular logic of pattern formation |
| title_alt | Cell Lineage vs. Intercellular Signaling Discs are not clones No part of a disc is a clone, except claws and tiny sense organs Cells belong to lineage "compartments" The Bristle Numb segregates asymmetrically and dictates bristle cell fates Delta needs to activate Notch, but not as a signal per se Amnesic cells can use sequential gating to simulate a binary code Notch must go to the nucleus to function E(spl)-C genes are Su(H) targets but play no role in the SOP lineage The transcription factor Tramtrack implements some cell identities Hairless titrated Su(H) Several other genes help determine the 5 cell fates Pox neuro and Cut specify bristle type Bract cells are induced by bristle cells |
| title_auth | Imaginal discs the genetic and cellular logic of pattern formation |
| title_exact_search | Imaginal discs the genetic and cellular logic of pattern formation |
| title_full | Imaginal discs the genetic and cellular logic of pattern formation Lewis I. Held, Jr |
| title_fullStr | Imaginal discs the genetic and cellular logic of pattern formation Lewis I. Held, Jr |
| title_full_unstemmed | Imaginal discs the genetic and cellular logic of pattern formation Lewis I. Held, Jr |
| title_short | Imaginal discs |
| title_sort | imaginal discs the genetic and cellular logic of pattern formation |
| title_sub | the genetic and cellular logic of pattern formation |
| topic | Drosophila melanogaster / Genetics Drosophila melanogaster / Embryology Drosophila melanogaster / Morphogenesis / Molecular aspects Cellular signal transduction Cell interaction Taufliege (DE-588)4078168-9 gnd Embryologie (DE-588)4014562-1 gnd Genetik (DE-588)4071711-2 gnd |
| topic_facet | Drosophila melanogaster / Genetics Drosophila melanogaster / Embryology Drosophila melanogaster / Morphogenesis / Molecular aspects Cellular signal transduction Cell interaction Taufliege Embryologie Genetik |
| url | https://doi.org/10.1017/CBO9780511529733 |
| work_keys_str_mv | AT heldlewisi imaginaldiscsthegeneticandcellularlogicofpatternformation |