Gene drives on the horizon: advancing science, navigating uncertainty, and aligning research with public values
"Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impac...
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Washington, DC
the National Academies Press
[2016]
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Zusammenfassung: | "Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators"--Publisher's description |
| Beschreibung: | xii, 217 Seiten Illustrationen |
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| 245 | 1 | 0 | |a Gene drives on the horizon |b advancing science, navigating uncertainty, and aligning research with public values |c Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct ; Board on Life Sciences, Division on Earth and LIfe Studies, the National Academies of Sciences, Engineering, Medicine |
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| 505 | 8 | |a Introduction -- The state of knowledge of the molecular biology, population genetics, and ecology of gene-drive modified organisms -- Case studies to examine questions about gene-drive modified organisms -- Charting human values -- Phased testing and scientific approaches to reducing potential harms of gene drives -- Assessing risks of gene-drive modified organisms -- Engaging communities, stakeholders, and publics -- Governing gene drive research and applications -- Gene drives on the horizon: overarching considerations -- Glossary -- Acronyms -- Appendix A: Agenda for the Workshop on the Science, Ethics and Governance Considerations for Gene Drive Research -- Appendix B: List of gene drive webinars -- Appendix C: Mosquito control strategies -- Appendix D: Rodent control strategies -- Appendix E: A brief history of ecological risk assessment -- Appendix F. Biographical sketches of Committee members | |
| 520 | |a "Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators"--Publisher's description | ||
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| 650 | 4 | |a Genetic engineering / Health aspects / Congresses | |
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| 650 | 4 | |a Transgenic organisms / Moral and ethical aspects / Congresses | |
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| 650 | 4 | |a Ethik | |
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Datensatz im Suchindex
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| adam_text | GENE DRIVES ON THE HORIZON
/
: 2016
TABLE OF CONTENTS / INHALTSVERZEICHNIS
INTRODUCTION
THE STATE OF KNOWLEDGE OF THE MOLECULAR BIOLOGY, POPULATION GENETICS,
AND ECOLOGY OF GENE-DRIVE MODIFIED ORGANISMS
CASE STUDIES TO EXAMINE QUESTIONS ABOUT GENE-DRIVE MODIFIED ORGANISMS
CHARTING HUMAN VALUES
PHASED TESTING AND SCIENTIFIC APPROACHES TO REDUCING POTENTIAL HARMS OF
GENE DRIVES
ASSESSING RISKS OF GENE-DRIVE MODIFIED ORGANISMS
ENGAGING COMMUNITIES, STAKEHOLDERS, AND PUBLICS
GOVERNING GENE DRIVE RESEARCH AND APPLICATIONS
GENE DRIVES ON THE HORIZON: OVERARCHING CONSIDERATIONS
GLOSSARY
ACRONYMS
APPENDIX A: AGENDA FOR THE WORKSHOP ON THE SCIENCE, ETHICS AND
GOVERNANCE CONSIDERATIONS FOR GENE DRIVE RESEARCH
APPENDIX B: LIST OF GENE DRIVE WEBINARS
APPENDIX C: MOSQUITO CONTROL STRATEGIES
APPENDIX D: RODENT CONTROL STRATEGIES
APPENDIX E: A BRIEF HISTORY OF ECOLOGICAL RISK ASSESSMENT
APPENDIX F. BIOGRAPHICAL SKETCHES OF COMMITTEE MEMBERS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| contents | Introduction -- The state of knowledge of the molecular biology, population genetics, and ecology of gene-drive modified organisms -- Case studies to examine questions about gene-drive modified organisms -- Charting human values -- Phased testing and scientific approaches to reducing potential harms of gene drives -- Assessing risks of gene-drive modified organisms -- Engaging communities, stakeholders, and publics -- Governing gene drive research and applications -- Gene drives on the horizon: overarching considerations -- Glossary -- Acronyms -- Appendix A: Agenda for the Workshop on the Science, Ethics and Governance Considerations for Gene Drive Research -- Appendix B: List of gene drive webinars -- Appendix C: Mosquito control strategies -- Appendix D: Rodent control strategies -- Appendix E: A brief history of ecological risk assessment -- Appendix F. Biographical sketches of Committee members |
| ctrlnum | (OCoLC)950893787 (DE-599)BVBBV043791685 |
| format | Book |
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| spelling | Gene drives on the horizon advancing science, navigating uncertainty, and aligning research with public values Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct ; Board on Life Sciences, Division on Earth and LIfe Studies, the National Academies of Sciences, Engineering, Medicine Washington, DC the National Academies Press [2016] xii, 217 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Introduction -- The state of knowledge of the molecular biology, population genetics, and ecology of gene-drive modified organisms -- Case studies to examine questions about gene-drive modified organisms -- Charting human values -- Phased testing and scientific approaches to reducing potential harms of gene drives -- Assessing risks of gene-drive modified organisms -- Engaging communities, stakeholders, and publics -- Governing gene drive research and applications -- Gene drives on the horizon: overarching considerations -- Glossary -- Acronyms -- Appendix A: Agenda for the Workshop on the Science, Ethics and Governance Considerations for Gene Drive Research -- Appendix B: List of gene drive webinars -- Appendix C: Mosquito control strategies -- Appendix D: Rodent control strategies -- Appendix E: A brief history of ecological risk assessment -- Appendix F. Biographical sketches of Committee members "Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators"--Publisher's description Genetic engineering / Moral and ethical aspects / Congresses Genetic engineering / Health aspects / Congresses Transgenic organisms / Risk assessment / Congresses Transgenic organisms / Moral and ethical aspects / Congresses Environmental health Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-Case Systems Organisms, Genetically Modified Genetic Engineering / ethics Risk Assessment Containment of Biohazards Safety Public Health Environmental Health Ethik (DE-588)1071861417 Konferenzschrift gnd-content LoC Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029202660&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gene drives on the horizon advancing science, navigating uncertainty, and aligning research with public values Introduction -- The state of knowledge of the molecular biology, population genetics, and ecology of gene-drive modified organisms -- Case studies to examine questions about gene-drive modified organisms -- Charting human values -- Phased testing and scientific approaches to reducing potential harms of gene drives -- Assessing risks of gene-drive modified organisms -- Engaging communities, stakeholders, and publics -- Governing gene drive research and applications -- Gene drives on the horizon: overarching considerations -- Glossary -- Acronyms -- Appendix A: Agenda for the Workshop on the Science, Ethics and Governance Considerations for Gene Drive Research -- Appendix B: List of gene drive webinars -- Appendix C: Mosquito control strategies -- Appendix D: Rodent control strategies -- Appendix E: A brief history of ecological risk assessment -- Appendix F. Biographical sketches of Committee members Genetic engineering / Moral and ethical aspects / Congresses Genetic engineering / Health aspects / Congresses Transgenic organisms / Risk assessment / Congresses Transgenic organisms / Moral and ethical aspects / Congresses Environmental health Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-Case Systems Organisms, Genetically Modified Genetic Engineering / ethics Risk Assessment Containment of Biohazards Safety Public Health Environmental Health Ethik |
| subject_GND | (DE-588)1071861417 |
| title | Gene drives on the horizon advancing science, navigating uncertainty, and aligning research with public values |
| title_auth | Gene drives on the horizon advancing science, navigating uncertainty, and aligning research with public values |
| title_exact_search | Gene drives on the horizon advancing science, navigating uncertainty, and aligning research with public values |
| title_full | Gene drives on the horizon advancing science, navigating uncertainty, and aligning research with public values Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct ; Board on Life Sciences, Division on Earth and LIfe Studies, the National Academies of Sciences, Engineering, Medicine |
| title_fullStr | Gene drives on the horizon advancing science, navigating uncertainty, and aligning research with public values Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct ; Board on Life Sciences, Division on Earth and LIfe Studies, the National Academies of Sciences, Engineering, Medicine |
| title_full_unstemmed | Gene drives on the horizon advancing science, navigating uncertainty, and aligning research with public values Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct ; Board on Life Sciences, Division on Earth and LIfe Studies, the National Academies of Sciences, Engineering, Medicine |
| title_short | Gene drives on the horizon |
| title_sort | gene drives on the horizon advancing science navigating uncertainty and aligning research with public values |
| title_sub | advancing science, navigating uncertainty, and aligning research with public values |
| topic | Genetic engineering / Moral and ethical aspects / Congresses Genetic engineering / Health aspects / Congresses Transgenic organisms / Risk assessment / Congresses Transgenic organisms / Moral and ethical aspects / Congresses Environmental health Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-Case Systems Organisms, Genetically Modified Genetic Engineering / ethics Risk Assessment Containment of Biohazards Safety Public Health Environmental Health Ethik |
| topic_facet | Genetic engineering / Moral and ethical aspects / Congresses Genetic engineering / Health aspects / Congresses Transgenic organisms / Risk assessment / Congresses Transgenic organisms / Moral and ethical aspects / Congresses Environmental health Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-Case Systems Organisms, Genetically Modified Genetic Engineering / ethics Risk Assessment Containment of Biohazards Safety Public Health Environmental Health Ethik Konferenzschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029202660&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |