Regulation of Membrane Na+-K+ ATPase:
Saved in:
| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
Cham
Springer International Publishing
2016
|
| Edition: | 1st ed. 2016 |
| Series: | Advances in Biochemistry in Health and Disease
15 |
| Subjects: | |
| Online Access: | BTU01 HTW01 UBR01 Volltext Inhaltsverzeichnis Abstract |
| Physical Description: | 1 Online-Ressource (XI, 436 p. 100 illus., 44 illus. in color) |
| ISBN: | 9783319247502 |
| DOI: | 10.1007/978-3-319-24750-2 |
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| 700 | 1 | |a Dhalla, Naranjan S. |e Sonstige |4 oth | |
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Record in the Search Index
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| adam_text | REGULATION OF MEMBRANE NA+-K+ ATPASE
/
: 2016
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PART A
1 NA+/K+-ATPASE: A PERSPECTIVE
2 NA+/K+-ATPASE AND ITS ROLE IN SIGNAL TRANSDUCTION
3 NA+ K+-ATPASE CELL SIGNALING PATHWAYS AND CANCER
4 CALCIUM CONTROLS THE P2-ATPASE MEDIATED HOMEOSTASIS: ESSENTIAL ROLE OF
NAAF
5 NA+/K+-ATPASE Α4: AN ISOFORM DEDICATED TO SPERM FUNCTION
6 THE ROLE OF THE 2ND NA+ PUMP IN MAMMALS AND PARASITES
7 MYOCARDIAL NA+/K+-ATPASE AND SERCA: CLINICAL AND PATHOLOGICAL
SIGNIFICANCE FROM A CYTOLOGICAL PERSPECTIVE
8 UNDERSTANDING THE DYSFUNCTION OF NA+/K+-ATPASE IN RAPID-ONSET
DYSTONIA- PARKINSONISM AND AMYOTROPHIC LATERAL SCLEROSIS
9 ACTIVITY OF MEMBRANE ATPASES IN HUMAN ERYTHROCYTES UNDER THE INFLUENCE
OF HIGHLY HYDROXYLATED FULLERENOL
10 XENOBIOTICS-MEDIATED MODULATION OF ATPASES AND BIOMEDICAL
IMPLICATIONS
11 EMERGING ROLE OF DYSADHERIN IN METASTASIS
12 THE ASTROCYTIC NA+/K+-ATPASE - STIMULATION BY INCREASED EXTRACELLULAR
K+, Β-ADRENERGIC ACTIVATION, OUABAIN-MEDIATED SIGNALING, AND
INTERACTION WITH THE TRANSPORTER NKCC1
13 UNCOUPLING OF P-TYPE ATPASES
14 PHOSPHOLEMMAN: A BRIEF OVERVIEW
15 REGULATION OF THE CARDIAC NA+/K+-ATPASE BY PHOSPHOLEMMAN
16 REGULATION OF BRAIN NA+/K+- ATPASE ACTIVITY BY NORADRENALINE WITH
PARTICULAR REFERENCE TO NORMAL AND ALTERED RAPID EYE MOVEMENT SLEEP
17 REGULATION NA+/K+-ATPASE ACTIVITY IN THE NERVOUS SYSTEM
18 REGULATION OF MEMBRANE NA+/K+ ATPASE IN HEALTH AND DISEASE
19 REDOX REGULATION OF THE NA+/K+ ATPASE IN THE CARDIOVASCULAR SYSTEM
20 REGULATION OF NA+/K+-ATPASE IN PULMONARY VASCULATURE
21 EXERCISE-INDUCED REGULATION OF THE NA, K-PUMP IN SKELETAL MUSCLES
22 ADVANCES IN THE UNDERSTANDING OF RENAL PROXIMAL TUBULAR NA+/K+-ATPASE
REGULATION BY PARATHYROID HORMONE AND DOPAMINE
23 REGULATION OF NA+/ K+-ATPASE IN EPITHELIAL-MESENCHYMAL TRANSITION AND
CANCER
24 METAL BASED COMPOUNDS, MODULATORS OF NA+/K+-ATPASE WITH ANTICANCER
ACTIVITY
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
REGULATION OF MEMBRANE NA+-K+ ATPASE
/
: 2016
ABSTRACT / INHALTSTEXT
NA+-K+ ATPASE OR NA-PUMP ATPASE, A MEMBER OF “P”-TYPE ATPASE
SUPERFAMILY, IS CHARACTERIZED BY ASSOCIATION OF MULTIPLE ISOFORMS MAINLY
OF IT’S Α- AND Β- SUBUNITS. AT PRESENT FOUR DIFFERENT Α-
(Α-1,Α-2,Α-3 AND Α-4) AND THREE Β- (Β-1, Β-2, AND Β-3) ISOFORMS
HAVE BEEN IDENTIFIED IN MAMMALIAN CELLS AND THEIR DIFFERENTIAL
EXPRESSIONS ARE TISSUE SPECIFIC. REGULATION OF NA+-K+ ATPASE ACTIVITY IS
AN IMPORTANT BUT A COMPLEX PROCESS, WHICH INVOLVES SHORT-TERM AND
LONG-TERM MECHANISMS. SHORT-TERM REGULATION OF NA+-K+ ATPASE IS EITHER
MEDIATED BY CHANGES IN INTRACELLULAR NA+ CONCENTRATIONS THAT DIRECTLY
AFFECT THE NA+-PUMP ACTIVITY OR BY
PHOSPHORYLATION/DEPHOSPHORYLATION-MEDIATED BY SOME STIMULANTS LEADING TO
CHANGES IN ITS EXPRESSION AND TRANSPORT PROPERTIES. ON THE OTHER HAND,
LONG-TERM REGULATION OF NA+-K+ ATPASE IS MEDIATED BY HORMONES, SUCH AS
MINERALOCORTICOIDS AND THYROID HORMONES, WHICH CAUSE CHANGES IN THE
TRANSCRIPTION OF GENES OF Α- AND Β- SUBUNITS LEADING TO AN INCREASED
EXPRESSION IN THE LEVEL OF NA+-PUMP. SEVERAL STUDIES HAVE REVEALED A
RELATIVELY NEW TYPE OF REGULATION THAT INVOLVES THE ASSOCIATION OF
SMALL, SINGLE SPAN MEMBRANE PROTEINS WITH THIS ENZYME. THESE PROTEINS
BELONG TO THE FXYD FAMILY, THE MEMBERS OF WHICH SHARE A COMMON SIGNATURE
SEQUENCE ENCOMPASSING THE TRANSMEMBRANE DOMAIN ADJACENT TO THE
ISOFORM(S) OF Α-Β SUBUNITS OF NA+-K+ ATPASE. CONSIDERING THE
EXTRAORDINARY IMPORTANCE OF NA+-K+ ATPASE IN CELLULAR FUNCTION, SEVERAL
INTERNATIONALLY ESTABLISHED INVESTIGATORS HAVE CONTRIBUTED THEIR
ARTICLES IN THE MONOGRAPH ENTITLED “REGULATION OF MEMBRANE NA+-K+
ATPASE” FOR INSPIRING YOUNG SCIENTISTS AND GRADUATE STUDENTS TO ENRICH
THEIR KNOWLEDGE ON THE ENZYME, AND WE ARE SURE THAT THIS BOOK WILL SOON
BE CONSIDERED AS A COMPREHENSIVE SCIENTIFIC LITERATURE IN THE AREA OF
NA+-K+ ATPASE REGULATION IN HEALTH AND DISEASE
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| isbn | 9783319247502 |
| language | English |
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| spelling | Regulation of Membrane Na+-K+ ATPase edited by Sajal Chakraborti, Naranjan S. Dhalla 1st ed. 2016 Cham Springer International Publishing 2016 1 Online-Ressource (XI, 436 p. 100 illus., 44 illus. in color) txt rdacontent c rdamedia cr rdacarrier Advances in Biochemistry in Health and Disease 15 Life sciences Molecular biology Proteins Cell membranes Atomic structure Molecular structure Spectra Life Sciences Protein Structure Membrane Biology Protein Science Atomic/Molecular Structure and Spectra Molecular Medicine Biowissenschaften Chakraborti, Sajal Sonstige oth Dhalla, Naranjan S. Sonstige oth Erscheint auch als Druckausgabe 978-3-319-24748-9 https://doi.org/10.1007/978-3-319-24750-2 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962381&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028962381&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Regulation of Membrane Na+-K+ ATPase Life sciences Molecular biology Proteins Cell membranes Atomic structure Molecular structure Spectra Life Sciences Protein Structure Membrane Biology Protein Science Atomic/Molecular Structure and Spectra Molecular Medicine Biowissenschaften |
| title | Regulation of Membrane Na+-K+ ATPase |
| title_auth | Regulation of Membrane Na+-K+ ATPase |
| title_exact_search | Regulation of Membrane Na+-K+ ATPase |
| title_full | Regulation of Membrane Na+-K+ ATPase edited by Sajal Chakraborti, Naranjan S. Dhalla |
| title_fullStr | Regulation of Membrane Na+-K+ ATPase edited by Sajal Chakraborti, Naranjan S. Dhalla |
| title_full_unstemmed | Regulation of Membrane Na+-K+ ATPase edited by Sajal Chakraborti, Naranjan S. Dhalla |
| title_short | Regulation of Membrane Na+-K+ ATPase |
| title_sort | regulation of membrane na k atpase |
| topic | Life sciences Molecular biology Proteins Cell membranes Atomic structure Molecular structure Spectra Life Sciences Protein Structure Membrane Biology Protein Science Atomic/Molecular Structure and Spectra Molecular Medicine Biowissenschaften |
| topic_facet | Life sciences Molecular biology Proteins Cell membranes Atomic structure Molecular structure Spectra Life Sciences Protein Structure Membrane Biology Protein Science Atomic/Molecular Structure and Spectra Molecular Medicine Biowissenschaften |
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