Bioisosteres in medicinal chemistry:
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first par...
Saved in:
| Other Authors: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Weinheim
Weinheim
2012
|
| Series: | Methods and principles in medicinal chemistry
54 |
| Subjects: | |
| Online Access: | DE-861 DE-188 DE-473 Volltext |
| Summary: | Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi |
| Physical Description: | 1 Online-Ressource (XVIII, 237 S.) Ill. |
| ISBN: | 9783527654338 9783527654321 9783527654314 9783527654307 9781280778537 |
Staff View
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| isbn | 9783527654338 9783527654321 9783527654314 9783527654307 9781280778537 |
| language | English |
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| spelling | Bioisosteres in medicinal chemistry ed. by Nathan Brown ... Weinheim Weinheim 2012 1 Online-Ressource (XVIII, 237 S.) Ill. txt rdacontent c rdamedia cr rdacarrier Methods and principles in medicinal chemistry 54 Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Drugs / Design fast Pharmaceutical chemistry fast Medizin Drugs / Design Pharmaceutical chemistry Pharmazeutische Chemie (DE-588)4132158-3 gnd rswk-swf Bioisosterie (DE-588)4145607-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Bioisosterie (DE-588)4145607-5 s Pharmazeutische Chemie (DE-588)4132158-3 s DE-604 Brown, Nathan edt Erscheint auch als Druck-Ausgabe 978-3-527-33015-7 Methods and principles in medicinal chemistry 54 (DE-604)BV044787818 54 https://onlinelibrary.wiley.com/doi/book/10.1002/9783527654307 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Bioisosteres in medicinal chemistry MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Drugs / Design fast Pharmaceutical chemistry fast Medizin Drugs / Design Pharmaceutical chemistry Pharmazeutische Chemie (DE-588)4132158-3 gnd Bioisosterie (DE-588)4145607-5 gnd Methods and principles in medicinal chemistry |
| subject_GND | (DE-588)4132158-3 (DE-588)4145607-5 (DE-588)4143413-4 |
| title | Bioisosteres in medicinal chemistry |
| title_auth | Bioisosteres in medicinal chemistry |
| title_exact_search | Bioisosteres in medicinal chemistry |
| title_full | Bioisosteres in medicinal chemistry ed. by Nathan Brown ... |
| title_fullStr | Bioisosteres in medicinal chemistry ed. by Nathan Brown ... |
| title_full_unstemmed | Bioisosteres in medicinal chemistry ed. by Nathan Brown ... |
| title_short | Bioisosteres in medicinal chemistry |
| title_sort | bioisosteres in medicinal chemistry |
| topic | MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Drugs / Design fast Pharmaceutical chemistry fast Medizin Drugs / Design Pharmaceutical chemistry Pharmazeutische Chemie (DE-588)4132158-3 gnd Bioisosterie (DE-588)4145607-5 gnd |
| topic_facet | MEDICAL / Drug Guides MEDICAL / Nursing / Pharmacology MEDICAL / Pharmacology MEDICAL / Pharmacy Drugs / Design Pharmaceutical chemistry Medizin Pharmazeutische Chemie Bioisosterie Aufsatzsammlung |
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