Biopharmaceutics modeling and simulations: theory, practice, methods, and applications
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Hoboken, N.J.
John Wiley & Sons
c2013
|
| Schlagworte: | |
| Online-Zugang: | FRO01 UBG01 URL des Erstveröffentlichers |
| Beschreibung: | Includes bibliographical references and index BA comprehensive introduction to using modeling and simulation programs in drug discovery and development/b/ Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation design, and toxicological exposure assessment, biopharmaceutical modeling is now seen as the linchpin to a drug's future success. And while there are a number of commercially available software programs for drug modeling, there has not been a single resource guiding pharmaceutical professionals to the actual tools and practices needed to design and test safe drugs./ A guide to the basics of modeling and simulation programs, iBiopharmaceutics Modeling and Simulations/i offers pharmaceutical scientists the keys to understanding how they work and are applied in creating drugs with desired medicinal properties. Beginning with a focus on the oral absorption of drugs, the book discusses:/ ulliThe central dogma of oral drug absorption (the interplay of dissolution, solubility, and permeability of a drug), which forms the basis of the biopharmaceutical classification system (BCS)/liliThe concept of drug concentration/liliHow to simulate key drug absorption processes/liliThe physiological and drug property data used for biopharmaceutical modeling/liliReliable practices for reporting results/li/ul With over 200 figures and illustrations and a peerless examination of all the key aspects of drug research'including running and interpreting models, validation, and compound and formulation selection'this reference seamlessly brings together the proven practical approaches essential to developing the safe and effective medicines of tomorrow |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9781118354315 1118354311 9781118354322 111835432X 9781118354308 1118354303 9781118354339 1118354338 1118028686 1118188330 9781299314597 1299314597 |
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Datensatz im Suchindex
| _version_ | 1804175972594876416 |
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| any_adam_object | |
| author | Sugano, Kiyohiko |
| author_facet | Sugano, Kiyohiko |
| author_role | aut |
| author_sort | Sugano, Kiyohiko |
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| dewey-full | 615.7 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.7 |
| dewey-search | 615.7 |
| dewey-sort | 3615.7 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Elektrotechnik / Elektronik / Nachrichtentechnik Medizin |
| format | Electronic eBook |
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| id | DE-604.BV043394252 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:24:47Z |
| institution | BVB |
| isbn | 9781118354315 1118354311 9781118354322 111835432X 9781118354308 1118354303 9781118354339 1118354338 1118028686 1118188330 9781299314597 1299314597 |
| language | English |
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| spelling | Sugano, Kiyohiko Verfasser aut Biopharmaceutics modeling and simulations theory, practice, methods, and applications Kiyohiko Sugano Hoboken, N.J. John Wiley & Sons c2013 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index BA comprehensive introduction to using modeling and simulation programs in drug discovery and development/b/ Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation design, and toxicological exposure assessment, biopharmaceutical modeling is now seen as the linchpin to a drug's future success. And while there are a number of commercially available software programs for drug modeling, there has not been a single resource guiding pharmaceutical professionals to the actual tools and practices needed to design and test safe drugs./ A guide to the basics of modeling and simulation programs, iBiopharmaceutics Modeling and Simulations/i offers pharmaceutical scientists the keys to understanding how they work and are applied in creating drugs with desired medicinal properties. Beginning with a focus on the oral absorption of drugs, the book discusses:/ ulliThe central dogma of oral drug absorption (the interplay of dissolution, solubility, and permeability of a drug), which forms the basis of the biopharmaceutical classification system (BCS)/liliThe concept of drug concentration/liliHow to simulate key drug absorption processes/liliThe physiological and drug property data used for biopharmaceutical modeling/liliReliable practices for reporting results/li/ul With over 200 figures and illustrations and a peerless examination of all the key aspects of drug research'including running and interpreting models, validation, and compound and formulation selection'this reference seamlessly brings together the proven practical approaches essential to developing the safe and effective medicines of tomorrow Biopharmaceutics / methods Computer Simulation Drug Compounding / methods Models, Theoretical Medical MEDICAL / Pharmacology bisacsh Medizin Biopharmaceutics / Computer simulation Bürstenloser Gleichstrommotor (DE-588)4164828-6 gnd rswk-swf Dauermagneterregung (DE-588)4428279-5 gnd rswk-swf Bürstenloser Gleichstrommotor (DE-588)4164828-6 s Dauermagneterregung (DE-588)4428279-5 s DE-604 Erscheint auch als Druck-Ausgabe, Hardcover 978-1-118-02868-1 Erscheint auch als Druck-Ausgabe, Hardcover 978-1-118-18833-0 https://onlinelibrary.wiley.com/doi/book/10.1002/9781118354339 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Sugano, Kiyohiko Biopharmaceutics modeling and simulations theory, practice, methods, and applications Biopharmaceutics / methods Computer Simulation Drug Compounding / methods Models, Theoretical Medical MEDICAL / Pharmacology bisacsh Medizin Biopharmaceutics / Computer simulation Bürstenloser Gleichstrommotor (DE-588)4164828-6 gnd Dauermagneterregung (DE-588)4428279-5 gnd |
| subject_GND | (DE-588)4164828-6 (DE-588)4428279-5 |
| title | Biopharmaceutics modeling and simulations theory, practice, methods, and applications |
| title_auth | Biopharmaceutics modeling and simulations theory, practice, methods, and applications |
| title_exact_search | Biopharmaceutics modeling and simulations theory, practice, methods, and applications |
| title_full | Biopharmaceutics modeling and simulations theory, practice, methods, and applications Kiyohiko Sugano |
| title_fullStr | Biopharmaceutics modeling and simulations theory, practice, methods, and applications Kiyohiko Sugano |
| title_full_unstemmed | Biopharmaceutics modeling and simulations theory, practice, methods, and applications Kiyohiko Sugano |
| title_short | Biopharmaceutics modeling and simulations |
| title_sort | biopharmaceutics modeling and simulations theory practice methods and applications |
| title_sub | theory, practice, methods, and applications |
| topic | Biopharmaceutics / methods Computer Simulation Drug Compounding / methods Models, Theoretical Medical MEDICAL / Pharmacology bisacsh Medizin Biopharmaceutics / Computer simulation Bürstenloser Gleichstrommotor (DE-588)4164828-6 gnd Dauermagneterregung (DE-588)4428279-5 gnd |
| topic_facet | Biopharmaceutics / methods Computer Simulation Drug Compounding / methods Models, Theoretical Medical MEDICAL / Pharmacology Medizin Biopharmaceutics / Computer simulation Bürstenloser Gleichstrommotor Dauermagneterregung |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/9781118354339 |
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